ACGIH (American Conference of Governmental Industrial Hygienists). 1997. Methyl Bromide in: Supplements to the Sixth Edition Documentation of the Threshold Limit Values and Biological Exposure Indices. Cincinnati, OH: ACGIH.

American Biogenics Corporation. 1986. Two-Generation Reproduction Study Via Inhalation in Albino Rats Using Methyl Bromide. Study 450– 1525. Submitted to Methyl Bromide Panel, c/o Great Lakes Chemical Corporation, W.Lafayette, IN. American Biogenics Corporation, Decatur, IL.

Anger, K.W., L.Moody, J.Burg, W.S.Brightwell, B.J.Taylor, J.M.Russo, N. Dickerson, J.V.Setzer, B.L.Johnson and K.Hicks. 1986. Neurobehavioral evaluation of soil and structural fumigators using methyl bromide and sulfuryl fluoride. Neurotoxicology 7(3):137–156. [PubMed: 3822255]

Bentley, K.S. 1994. Detection of Single Strand Breaks in Rat Testicular DNA by Alkaline Elution Following in Vivo Inhalation Exposure to Methyl Bromide. Haskell Laboratory Report No. 54–94. Chemical Manufacturers Association. DPR Vol. 123–188 #162362.

Biermann, H.W. and T.Barry. 1999. Evaluation of Charcoal Tube and SUMMA Canister Recoveries for Methyl Bromide Air Sampling. Environmental and Pest Management Branch. DPR. EH99–02 (Appendix K of DPR 1999).

Bond, J.A., J.S.Dutcher, M.A.Medinsky, R.F.Henderson, and L.S. Birnbaum. 1985. Disposition of ¹⁴C methyl bromide in rats after inhalation. Toxicol. Appl. Pharmacol. 78(2):259–267. [PubMed: 4035680]

Bonnefoi, M.S., C.J.Davenport, and K.T.Morgan. 1991. Metabolism and toxicity of methyl iodide in primary dissociated neural cell cultures. Neurotoxicology. 12(1):33–46. [PubMed: 2014067]

Breslin, W.J., C.L.Zablotny, G.J.Bradley, K.D.Nitschke, and L.G.Lomax. 1990. a. Methyl Bromide Inhalation Teratology Probe Study in New Zealand White Rabbits. Final Report. K-000681–032. Study prepared by The Toxicology Research Laboratory, The Dow Chemical Company, Midland, MI for The Methyl Bromide Industry Panel, Chemical Manufacturers Association, Washington, DC.

Breslin, W.J., C.L.Zablotny, G.J.Bradley, and L.G.Lomax. 1990. b. Methyl Bromide Inhalation Teratology Study in New Zealand White Rabbits. Final Report. K-000681–033. Study prepared by The Toxicology Research Laboratory, The Dow Chemical Company, Midland, MI for The Methyl Bromide Industry Panel, Chemical Manufacturers Association, Washington, DC.

Busey, W.M. 1993. Neuropathological Evaluation of Brains from F0 and F1 Rats in Two-generation Reproduction Study with Methyl Bromide Pathology Report. EPL project number 303–007. DPR Vol. 123–153 #125516.

Chahoud, I., A.Ligensa, L.Dietzel and A.S.Faqi. 1999. Correlation between maternal toxicity and embryo/fetal effects. Reprod. Toxicol. 13(5):375– 381. [PubMed: 10560586]

Cullen, A.C. and H.C.Frey. 1999. Probabilistic Techniques in Exposure Assessment. A Handbook for Dealing with Variability and Uncertainty in Models and Inputs. New York: Plenum Press.

Disse, M., F.Joo, H.Schulz and J.R.Wolff. 1996. Prenatal exposure to sodium bromide affects the postnatal growth and brain development. J. Hirnorsch. 37(10):127–134. [PubMed: 8964971]

Djalali-Behzad, G., S.Hussain, S.Osterman-Golkar, and D.Segerback. 1981. Estimation of genetic risks of alkylating agents. VI. Exposure of mice and bacteria to methyl bromide. Mutat. Res. 84(1):1–9. [PubMed: 7035924]

Donahue, J.M. 1997. DPR letters dated November 12. (Letters were sent to six MB registrants requesting data on frequency and duration of exposure). WH&S. DPR.

DPR (Department of Pesticide Regulation). 1992. Toxicology Review Prompts Changes in Structural Fumigations. Release no. 92–07. Department of Pesticide Regulation, California Environmental Protection Agency.

DPR (Department of Pesticide Regulation). 1999. Methyl Bromide, Risk Characterization Document for Inhalation Exposure. Draft RCD 99–02. Department of Pesticide Regulation, California Environmental Protection Agency. October 1999.

Driscoll, C.D. and J.M.Hurley. 1993. Methyl Bromide: Single Exposure Vapor Inhalation Neurotoxicity Study in Rats. Lab. Project ID 92N1197. Study prepared by Bushy Run Research Center, Union Carbide Chemicals and Plastics Company, Export, PA for The Methyl Bromide Industry Panel, Chemical Manufacturers Association, Washington, DC.

EPA (U.S. Environmental Protection Agency). 1989. Risk Assessment Guidance for Superfund, Vol. I. Human Health Evaluation Manual, Part A. EPA/540/1–89/002. Washington, DC: EPA, Office of Emergency and Remedial Response.

EPA (U.S. Environmental Protection Agency). 1991. Guidelines for Developmental Toxicity Risk Assessment. EPA/600/FR-91/001. Washington, DC: EPA, Office of Research and Development.

EPA (U.S. Environmental Protection Agency). 1994. Methods for Derivation of Inhalation Reference Concentrations and Application of Inhalation Dosimetry. EPA/600/8–90/066F. Washington, D.C.: EPA, Office of Research and Development.

EPA (U.S. Environmental Protection Agency). 1995. User's Guide for the Industrial Source Complex (ISC3) Dispersion Models. Volume 1. User Instructions. U.S. EPA Office of Air Quality Planning and Standards; Emissions, Monitoring and Analysis Division, Research Triangle Park, North Carolina. Online. Available: www​.epa.gov/ttn/scram/

EPA (U.S. Environmental Protection Agency). 1996. The Particle TEAM (PTEAM) Study: Analysis of the Data: Final Report. Volume III. EPA/600/R-95/098. Research Triangle Park, NC: EPA, Office of Research and Development.

EPA (U.S. Environmental Protection Agency). 1997. Good Laboratory Practices. 40 Code of Federal Regulations, Part 160.

Eustis, S.L., S.B.Haber, R.T.Drew, and R.S.Yang. 1988. Toxicology and pathology of methyl bromide in F344 rats and B6C3F1 mice following repeated inhalation exposure. Fundam. Appl. Toxicol. 11(4):594–610. [PubMed: 3229585]

Gansewendt, B., U.Foest, D.Xu, E.Hallier, H.M.Bolt, and H.Peter. 1991. Formation of DNA adducts in F-344 rats after oral administration or inhalation of [¹⁴C] methyl bromide. Food Chem. Toxicol. 29(8):557–563. [PubMed: 1894222]

Garnier, R., M.O.Rambourg-Schepens, A.Muller and E.Hallier. 1996. Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Occup. Environ. Med. 53(3):211–215. [PMC free article: PMC1128446] [PubMed: 8704864]

Gibbons, D.B., H.R.Fong, R.Segawa, S.Powell and J.Ross. 1996. a. Methyl Bromide Concentrations in Air Downwind During Aeration of Fumigated Single-Family Houses. HS-1713. March 20, 1996. Worker Health and Safety Branch. Department of Pesticide Regulation. California Environmental Protection Agency, Sacramento, CA.

Gibbons, D.B., H.R.Fong, R.Segawa, S.Powell, and J.Ross. 1996. b. Methyl Bromide Concentrations in Air Near Fumigated Single-Family Houses. HS-1717. March 20, 1996. Worker Health and Safety Branch. Department of Pesticide Regulation. California Environmental Protection Agency. Sacramento, CA.

Gotoh, K., T.Nishizawa, T.Yamaguchi, H.Kanou, T.Kasai, M.Ohsawa, H. Ohbayashi, S.Also, N.Ikawa, S.Yamamoto, T.Noguchi, K.Nagano, M. Enomoto, K.Nozaki, and H.Sakabe. 1994. Two-Year Toxicological and Carcinogenesis Studies of Methyl Bromide in F344 rats and BDF1 Mice. Proceedings of the Second Asia-Pacific Symposium on Environmental and Occupational Health held 22–24 July, 1993 in Kobe, Japan.

Hallier, E., S.Deutschmann, C.Reichel, H.M.Bolt and H.Peter. 1990. A comparative investigation of the metabolism of methyl bromide and methyl iodide in human erythrocytes. Int. Arch. Occup. Environ. Health. 62(3): 221–225. [PubMed: 2347645]

Hallier, E., T.Langhof, D.Dannappel, M.Leutbecher, K.Schroder, H.W. Goergens, A.Muller and H.M.Bolt. 1993. Polymorphism of glutathione conjugation of methyl bromide, ethylene oxide and dichloromethane in human blood: influence on the induction of sister chromatid exchanges (SCE) in lymphocytes. Arch. Toxicol. 67(3):173–178. [PubMed: 8494496]

Hardisty, J.F. 1992. Histopathological Evaluation of Brains From Rats-Inhalation Study of Methyl-Bromide. EPL project number 303–007. DPR Vol. 123–142 #113606.

Haskell, D. 1988. a. Methyl bromide fumigation with various commodities. A memorandum dated May 11 to Thomas Thongsinthusak. WH&S, DPR. HSM-98003.

Haskell, D. 1988. b. Response to DAR request for additional information regarding frequency and duration of methyl bromide fumigations. A memorandum date August 24 to Thomas Thongsinthusak. WH&S, DAR. HSM-98006.

Hattis, D. and E.Anderson. 1999. What should be the implications of uncertainty, variability, and inherent ‘biases'/'conservatism' for risk management decision making? Risk Anal. 19(1):95–107.

Hattis, D. and K.Barlow. 1996. Human interindividual variability in cancer risks-technical and management challenges. Human Ecol. Risk Asssess 2(1):194–220.

Hattis, D. and D.E.Burmaster. 1994. Assessment of variability and uncertainty distributions for practical risk analyses. Risk Anal. 14(5):713–730.

Honma, T., M.Miyagawa, and M.Sato. 1987. Methyl bromide alters catecholamine and metabolite concentrations in rat brain. Neurotoxicol. Teratol. 9(5):369–375. [PubMed: 2447477]

Honma, T., M.Miyagawa, and M.Sato. 1991. Inhibition of tyrosine hydroxylase activity by methyl bromide exposure. Neurotoxicol. Teratol. (13)1:1–4. [PubMed: 1675421]

Honma, T., A Sudo, M.Miyagawa, M.Sato, and H.Hasegawa. 1982. Significant changes in monoamines in rat brain induced by exposure to methyl bromide. Neurobehav. Toxicol. Teratol. 4(5):521–524. [PubMed: 6129581]

Hurtt, M.E., D.A.Thomas, P.K.Working, T.M.Monticello, and K.T.Morgan. 1988. Degeneration and regeneration of the olfactory epithelium following inhalation exposure to methyl bromide: Pathology, cell kinetics, and olfactory function. Toxicol. Appl. Pharmacol. 94(2):311–328. [PubMed: 2455365]

Jaskot, R.H., E.C.Grose, B.M.Most, M.G.Menache, T.B.Williams, and J.J. Roycroft. 1988. The distribution and toxicological effects of inhaled methyl bromide in the rat. J. Am. Coll. Toxicol. 7(5):631–642.

Kaneda, M., N.Hatakenaka S.Teramoto, and K.Maita. 1993. A two-generation reproduction study in rats with methyl bromide-fumigated diets. Food Chem. Toxicol. 31(8):533–542. [PubMed: 8349198]

Kaneda, M., H.Hojo, S.Teramoto, and K.Maita. 1998. Oral teratogenicity studies of methyl bromide in rats and rabbits. Food Chem. Toxicol. 36(5):421–427. [PubMed: 9662417]

Khera, K.S. 1984. Maternal toxicity: a possible factor in fetal malformations in mice. Teratology 29(3):411–16. [PubMed: 6379969]

Khera, K.S., editor; , H.C.Grice HC, editor; , and D.J.Clegg, editor. , eds. 1989. Current Issues in Toxicology, Interpretation and Extrapolation of Reproductive Data to Establish Human Safety Standards. New York: Springer.

Kornburst, K.S., and J.S.Bus. 1983. The role of glutathione and cytochrome P-450 in the metabolism of methyl chloride. Toxicol. Appl. Pharmacol. 67(2):246–56. [PubMed: 6836579]

Kramers, P.G., C.E.Voogd, A.G.Knaap, and C.A.van der Heijden. 1985. Mutagenicity of methyl bromide in a series of short-term test. Mutat. Res. 155(1–2):41–47. [PubMed: 3918260]

McGregor, D.B. 1981. Tie II Mutagenic Screening of 13 NIOSH Priority Compounds. National Institute for Occupational Safety Health. Inveresk Research Int. Ltd. DAR Vol. 123–103 #66718, #66719, #66720, #66721, and #66722.

Medinsky, M.A., J.A.Bond, J.S.Dutcher, and L.S.Birnbaum. 1984. Disposition of [¹⁴C] methyl bromide in Fischer-344 rats after oral or intraperitoneal administration. Toxicology. 32(3):187–196. [PubMed: 6433513]

Medinsky, M.A., J.S.Dutcher, J.A.Bond, R.F.Henderson, J.L.Mauderly, M.B.Snipes, J.A.Mewhinney, Y.S.Cheng, and L.S.Birnbaum. 1985. Uptake and excretion of [14C] methyl bromide as influenced by exposure concentration. Toxicol. Appl. Pharmacol. 78(2):215–225. [PubMed: 4035677]

Mertens, J.J.W.M. 1997. A 24-Month Chronic Dietary Study of Methyl Bromide in Rats. Laboratory Study no. WIL-49014. WIL Research Laboratories. DAR Vol. 123–179 #158746.

Michalodimitrakis, M.N., A.M.Tsatsakis, M.G.Christakis-Hampsas, N. Trikillis, and P.Christodoulou. 1997. Death following intentional methyl bromide poisoning: toxicological data and literature review. Vet. Hum. Toxicol. 39(1):30–34. [PubMed: 9004465]

Mitsumori, K., K.Maita, T.Kosaka, T.Miyaoka, and Y.Shirasu. 1990. Two-year oral chronic toxicity and carcinogenicity study in rats of diets fumigated with methyl bromide. Food Chem. Toxicol. 28(2):109–119. [PubMed: 2341089]

Moriya, M., T.Ohta, K.Watanabe, T.Miyazawa, K.Kato, Y.Shirasu. 1983. Further mutagenicity studies on pesticides in bacterial reversion assay systems. Mutat. Res. 116(3–4):185–216. [PubMed: 6339892]

Mortelmans, K.E., and G.F.Shepherd. 1980. In Vitro Microbiological Mitotic Recombination Assay of Methyl Bromide Using S. cereisiae D3. SRI International. DAR Vol. 123–044 #913095.

NRC (National Research Council). 1991. Human Exposure Assessment for Airborne Pollutants: Advances and Opportunities. Washington, DC: National Academy Press.

NRC (National Research Council). 1993. Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press. [PubMed: 25144038]

NRC (National Research Council). 1994. Science and Judgement in Risk Assessment. Washington, DC: National Academy Press. [PubMed: 25032408]

Nelson, H.H., J.K.Wiencke, D.C.Christiani, T.J.Cheng, Z.F.Zuo, B.S. Schwartz, B.K.Lee, M.R.Spitz, M.Wang, X.Xu, et al. 1995. Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis 16(5):1243–1245. [PubMed: 7767992]

Newton, P.E. 1994. a. An Up-and-Down Acute Inhalation Toxicity Study of Methyl Bromide in the Dog. Study no. 93–6067 prepared by Pharmaco LSR, East Millstone, NJ for Chemical Manufacturers Association, Washington, DC.

Newton, P.E. 1994. b. A Four Week Inhalation Toxicology Study of Methyl Bromide in the Dog. Study no. 93–6068 prepared by Pharmaco LSR, East Millstone, NJ for Chemical Manufacturers Association, Washington, DC.

Newton, P.E. 1996. A Chronic (12-Month) Toxicity Study of Methyl Bromide Fumigated Feed in the Dog. Study no. 94–3186. Huntingdon Life Science. DAR Vol. 123–175. #143945.

NTP. (National Toxicology Program). 1992. Toxicology and Carcinogenesis Studies of Methyl Bromide (CAS No. 74–83–9) in B6C3F1 Mice (Inhalation Studies). Tech. Rep. Series No. 385. Research Triangle Park: U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health.

OEHHA (Office of Environmental Health Hazard Assessment). 1993. Proposition 65: Safe Use Determination Workshop for Methyl Bromide (Tuesday November 30, 1993.) Transcript. California Environmental Protection Agency, Office of Environmental Health Hazard Assessment. 205 pp.

OEHHA (Office of Environmental Health Hazard Assessment). 1999. Comments on the Department of Pesticide Regulation's Draft Risk Characterization Document for Inhalation Exposure to the Active Ingredient Methyl Bromide. From Anna M.Fan, California Office of Environmental Health Hazard Assessment, to Gary T.Patterson, California Department of Pesticide Regulation, September 1, 1999 (Appendix L of DPR 1999).

Overstreet, D.H., R.W.Russell, B.J.Vasquez, and F.W.Dalglish. 1974. Involvement of muscarinic and nictonic receptors in behavioral tolerance to DFP. Pharmacol. Biochem. Behav. 2(1):45–54. [PubMed: 4828482]

Peter, H., S.Deutschmann, C.Reichel, and E.Hallier. 1989. Metabolism of methyl chloride by human erythrocytes. Arch. Toxicol. 63(5):351–5. [PubMed: 2818198]

Putnam, D.L. and M.J.Morris. 1991. Micronucleus Cytogenetic Assay in Mice. Microbiological Assoc. Inc. DAR Vol. 123–136 #99090.

Raabe, O.G. 1986. Inhalation Uptake of Selected Chemical Vapors at Trace Levels. University of California, Davis, C A. Submitted to The Biological Effects of Research Section, California Air Resources Board, Sacramento, CA.

Raabe, O.G. 1988. Retention and Metabolism of Toxics. Inhalation uptake of Xenobiotic Vapors by People. University of California, Davis, CA. Submitted to The Biological Effects Research Section, California Air Resources Board, Sacramento, CA.

Reuzel, P.G.J., C.F.Kuper, H.C.Dreef-van der Meulen, V.M.H.Hollanders. 1987. Chronic (29-Month) Inhalation Toxicity and Carcinogenicity Study of Methyl Bromide in Rats. Report No. V86.469/221044. Zeist, The Netherlands: TNO-CIVO Toxicology and Nutrition Institute.

Reuzel, P.G.J., H.C.Dreef-van der Meulen, V.M.H.Hollanders, C.F.Kuper, V.J.Feron, and C.A. and van der Heijden. 1991. Chronic Inhalation Toxicity and Carcinogenicity Study of Methyl Bromide in Wistar Rats. Food Chem. Toxicol. 29(1):31–39. [PubMed: 1825644]

Rosenblum, I., A.A.Stein, and G.Eisinger. 1960. Chronic ingestion by dogs of methyl bromide-fumigated food. Arch. Environ. Health 1:316–323. [PubMed: 13743429]

Segawa, R., T.Barry, and B.Johnson. 2000. a. Recommendations for Methyl Bromide Buffer Zones for Field Fumigations. Memo to John S.Sanders, Chief, Environmental Monitoring and Pest Management Branch, Department of Pesticide Regulation, January 21, 2000.

Segawa, R., B.Johnson, and T.Barry. 2000. b. Summary of off-site air monitoring for methyl bromide field fumigations. Memo to John S.Sanders, Chief, Environmental Monitoring and Pest Management Branch, Department of Pesticide Regulation, January 21, 2000.

Seiber, J.N. 1999. Letter to Douglas Y.Okumura, Acting Assistant Director, Division of Enforcement, Environmental Monitoring and Data Management, Department of Pesticide Regulation. Comments on report, Evaluation of Charcoal Tube and SUMMA Canister Recoveries for Methyl Bromide Air Monitoring, from James N.Seiber, University of Nevada, May 5, 1999.

Sikov, M.R., W.C.Cannon, D.B.Carr, R.A.Miller, L.F.Montgomery, and D.W.Phelps. 1981. Teratologic Assessment of Butylene Oxide, Styrene Oxide and Methyl Bromide. Contract no. 210–78–0025. Battelle, Pacific Northwest Lab. Submitted to the Division of Biomedical and Behavioral Science, National Institute for Occupational Safety and Health, U.S. Department of Health and Human Services, Cincinnati, OH.

Simmon, V.F., K.Kauhanen, R.G.Tardiff. 1977. Mutagenic activity of chemicals identified in drinking water. Pp. 249–258 in: Progress in Genetic Toxicology, D.Scott, editor; , B.A.Bridges, editor; , and F.H.Sobels, editor. , eds. Amsterdam: Elsevier/North Holland Biodmedical Press. DAR Vol 123–109 #87801.

Stadler, J., M.J.Kessedjian, and J.Perraud. 1983. Use of the New Zealand white rabbit in teratology: Incidence of spontaneous and drug-induced malformations. Food Chem. Toxicol. 21(5):631–636. [PubMed: 6686190]

Thompson, K.M. 1999. Developing univariate distributions from data for risk analysis. Human Ecol. Risk Assess. 5(4):755–783.

Thongsinthusak, T., D.Haskell, and J.Ross. 1999. Estimation of exposure of persons to methyl bromide during and/or after agricultural and non-agricultural uses. California Environmental Protection Agency, Department of Pesticide Regulation. HS-1659 (Appendix F of DPR 1999).

Tyl, R. 1991. Comments on Methyl Bromide Inhalation Teratology Study in New Zealand White Rabbits, W.J.Breslin, editor; , C.L.Zablotny, editor; , G.J.Bradley, editor; , and L.G.Lomax, editor. , Toxicology Research Laboratory, Health and Environmental Sciences, The Dow Chemical Company, Midland, MI: Study No. K-000681–033, Final Report, June 18, 1990 by R.W.Tyl, Senior Program Director, Research Triangle Institute to Dr. R.Franklin Handy, Methyl Bromide Industry Panel, Great Lakes Chemical Corporation, dated February 25, 1991. 31pp.