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National Academies of Sciences, Engineering, and Medicine; Division on Earth and Life Studies; Board on Environmental Studies and Toxicology; Committee on Endocrine-Related Low-Dose Toxicity. Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals. Washington (DC): National Academies Press (US); 2017 Jul 18.

Cover of Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals

Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals.

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Abbreviations and Acronyms

ADHD

attention deficit/hyperactivity disorder

ADR

adverse drug reaction

AGD

anogenital distance

AGD ap

anogenital distance (anopenile)

AGD as

anogenital (anoscrotal)

AGI

anogenital index

AHRQ

Agency for Healthcare Research and Quality

AICc

Akaieke information criterion corrected

AOP

adverse outcome pathway

APD

anopenile distance

ASD

anoscrotoal distance

BASC-2

Behavioral Assessment System for Children-2

BDE

brominated diphenyl ether

BMD

benchmark dose

BMDL

benchmark dose modeling

BMR

benchmark response

BPA

bisphenol A

BzBP

benzylbutyl phthalate

CADS-P

Conners' ADHD Index (derived from Conners' Parent Rating Scale)

CASTNET

Clean Air Status and Trends Network

CBCL

Child Behavior Checklist

CDC

US Centers for Disease Control and Prevention

CI

confidence interval

COI

conflict of interest

cpAOP

computationally predicted adverse outcome pathway

CPRS

Conners' Parent Rating Scale‐Revised

CPT II

Conners' Continuous Performance Test II

CRS‐T

Conners' Rating Scale‐Teachers

DBD

Disruptive Behavior Disorders Rating Scale

DBP

dibutyl phthalate

DEHP

di(2-ethylhexyl) phthalate

DEP

diethyl phthalate

DES

diethylstilbestrol

DIBP

diisobutyl phthalate

DIDP

diisodecyl phthalate

DINP

diisononyl phthalate

DIOP

diisooctyl phthalate

DMP

dimethyl phthalate

DNOP

di-n-octylphthalate

DPP

dipentyl phthalate

EAC

endocrine active chemical

EDSP

Endocrine Disruptor Screening Program

EFSA

European Food Safety Authority

EPA

US Environmental Protection Agency

ExpoCast

EPA's computer model to predict chemical exposure

FAERS

FDA Adverse Event Reporting System

FDA

US Food and Drug Administration

FQPA

Food Quality Protection Act (of 1996)

GRADE

Grading of Recommendations, Assessment, Development and Evaluation

HAWC

Health Assessment Workspace Collaborative

INSL-3

insulin-like 3

IRIS

Integrated Risk Information System

K‐CPT

Conners' Kiddie Continuous Performance Test

LOAEL

lowest-observed-adverse-effect level

LOEL

lowest-observed-effect level

MBP

monobutylphthalate

MBzP

mono-benzyl phthalate

MCNP

mono-(carboxynonyl) phthalate

MCOP

mono-carboxy-isooctyl phthalate

MCPP

mono-(3-carboxypropyl) phthalate

MECPP

mono-(2-ethyl-5-carboxypentyl) phthalate

MEHP

mono-2-ethylhexyl phthalate

MEP

mono-ethyl phthalate

MeO-BDE

methoxylated BDE

MeSH

medical subject heading

MIBP

mono-isobutyl phthalate

MMP

mono-methyl phthalate

MSCA

McCarthy Scales of Children's Abilities

NHANES

National Health and Nutrition Examination Survey

NMDR

nonmonotonic dose-response

NOAEL

no-observed-adverse-effect level

NOEL

no-observed-effect level

NRC

National Research Council

NTP

National Toxicology Program

OECD

Organisation for Economic Co-operation and Development

OH-BDE

hydroxylated BDE

OHAT

National Toxicology Program's Office of Health Assessment and Translation

PBDE

polybrominated diphenyl ether

PBPK

physiologically based pharmacokinetic

PCB

polychlorinated biphenyl

PECO

Population, Exposure, Comparator, and Outcome

PM

particulate matter

PND

postnatal day

QSAR

quantitative structure-activity relationship

RE

random effects

RfD

reference dose

ROM

ratio of means

RR

relative risk

SD

standard deviation

TCDD

2,3,7,8-tetrachlorodibenzo-p-dioxin

ToxCast

Toxicity Forecaster

VAERS

Vaccine Adverse Event Reporting System

WHO

World Health Organization

WISC

Wechsler Intelligence Scale for Children

WPPSI

Wechsler Preschool and Primary Scale of Intelligence

Copyright 2017 by the National Academy of Sciences. All rights reserved.
Bookshelf ID: NBK453248

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