Building on earlier workshops on severe acute respiratory syndrome in 2002, the H1N1 influenza pandemic of 2009, and the emergence of Middle East respiratory syndrome coronavirus in the Arabian Peninsula, an ad hoc committee will host a public workshop on the Ebola hemorrhagic fever epidemic in Africa to inform the Forum on Microbial Threats and other participants about recent developments in the incidence, prevalence, and intervention strategies being employed to mitigate this disease in the face of an increasingly interconnected world. The public workshop will feature invited presentations and discussions that will focus on such potential topics as the source(s) and spread of this disease from its epicenter to other countries in West Africa; factors driving the unprecedented scale of this outbreak; factors impeding country responses; whether the international community (including the United States) has responded in an effective and coordinated manner to lessen the geographic spread of this disease to other parts of Africa and beyond; and prospects for the development of treatments against a genomically evolving viral target. An ad hoc committee will plan and conduct the 2-day public workshop, and an individually authored Proceedings of a Workshop will be prepared by a designated rapporteur in accordance with institutional policy and procedures.