This newly revised edition incorporates the regulatory requirements and improved practices for laboratory animal care that have developed over the past two decades.

The volume covers

• Selection of dogs as research models.
• Design, construction, and maintenance of facilities.
• Temperature, humidity, food, water, bedding, sanitation, animal identification, record keeping, and transportation.
• General veterinary care, as well as special care of breeding animals and random-source animals.

Laboratory Animal Management:Dogs discusses how to assemble a proper research protocol and how to handle conflicts. Outlined are procedures for institutional animal care and use and committee review. The volume also presents guidelines for handling aging dogs, use of radiation in experiments, and a wide range of other special circumstances.

Thoroughly referenced, this guide will be indispensable to researchers, research administrators, review committees, and others concerned about laboratory dogs.

Contents

• COMMITTEE ON DOGS
• CONTRIBUTORS
• INSTITUTE OF LABORATORY ANIMAL RESOURCES COUNCIL
• COMMISSION ON LIFE SCIENCES
• The National Academies
• Preface
• 1. Introduction
  • References
• 2. Criteria for Selecting Experimental Animals
  • Genetic Factors
  • Biologic Factors
  • Behavioral Factors
  • Hazards
  • References
• 3. Husbandry
  • Housing
  • Exercise and Environmental Enrichment
  • Food
  • Water
  • Bedding and Resting Apparatuses
  • Sanitation
  • Identification and Records
  • Emergency, Weekend, and Holiday Care
  • Transportation
  • References
• 4. Management of Breeding Colonies
  • Reproduction
  • Neonatal Care
  • Reproductive Problems
  • Special Nutritional Requirements
  • Vaccination and Deworming
  • Socialization of Pups
  • Record Keeping
  • References
• 5. Veterinary Care
  • Procurement
  • Control of Infectious Diseases
  • Control of Parasitic Diseases
  • Recognition and Alleviation of Pain and Distress
  • Surgery and Postsurgical Care
  • Euthanasia
  • References
• 6. Special Considerations
  • Protocol Review
  • Restraint
  • Special Care for Animal Models
  • References
• Appendix. Cross Reference

NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, National Academy of Engineering, and Institute of Medicine. The members of the committee responsible for the report were chosen for their special competencies and with regard for appropriate balance.

This report has been reviewed by a group other than the authors according to procedures approved by a Report Review Committee consisting of members of the National Academy of Sciences, National Academy of Engineering, and Institute of Medicine.

Any opinions, findings, and conclusions or recommendations expressed in this publication are those of the committee and do not necessarily reflect the views of DHHS, USDA, or other sponsors, nor does the mention of trade names, commercial products, or organizations imply endorsement by the U.S. government or other sponsor.