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Institute of Medicine (US) Forum on Microbial Threats. The Science and Applications of Microbial Genomics: Workshop Summary. Washington (DC): National Academies Press (US); 2013.

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The Science and Applications of Microbial Genomics: Workshop Summary.

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Appendix BAgenda

The Science and Applications of Microbial Genomics

June 12–13, 2012

500 Fifth Street, NW

Washington DC

DAY ONE. TUESDAY, JUNE 12, 2012

8:45–9:15:Registration and Continental Breakfast
9:15–9:30:Welcoming Remarks: David Relman, James Hughes, and Lonnie King
9:30–10:00:KEYNOTE: Yersinia pestis Population Genetics Across Time and Space
Paul Keim, Northern Arizona University
10:00–10:20:Discussion
10:20–10:30:BREAK

SESSION I. Microbial Genomics—Diversity, Evolution, and Adaptation

Arturo Casadevall, Moderator
10:30–11:00:The Earth Microbiome Project: Modeling the Earth’s Microbiome
Jack A. Gilbert, Argonne National Laboratory/University of Chicago
11:00–11:30:Variation in Microbial Communities and Genomes
George Weinstock, Washington University in St. Louis
11:30–12:00:Population Diversity in Deep-Sea Microbial Communities
Peter Girguis, Harvard University
12:00–12:30:The Application of Computational/Theoretical and Experimental Approaches to Study the Evolution of Microorganisms
Eric Alm, Massachusetts Institute of Technology
12:30–1:00:Discussion
1:00–1:45:LUNCH

SESSION II. Microbial Genomics—Molecular Mechanisms of Disease Emergence and Epidemiology

David Relman, Moderator
1:45–2:15:Characterizing Intra-host Influenza Virus Populations to Predict Emergence
Elodie Ghedin, University of Pittsburgh School of Medicine
2:15–2:45:Identifying Signatures of Recent Selection and Transmission in Pathogenic Bacteria
Julian Parkhill, The Sanger Institute
2:45–3:15:Comparative Genomics of E. coli and Shigella: Identification and Characterization of Pathogenic Variants Based on Whole Genome Sequence Analysis
David Rasko, University of Maryland Institute for Genome Sciences
3:15–3:45:BREAK
3:45–4:15:Coral Health and Disease in the Face of Climate Change
Kim Ritchie, Mote Marine Laboratory
4:15–4:45:Evolution and Pathogenicity in the Deadly Chytrid Pathogen of Amphibians
Erica Bree Rosenblum, University of California–Berkeley
4:45–5:15:Discussion
5:15–6:00:Concluding Remarks
6:15:ADJOURN DAY ONE

DAY TWO. WEDNESDAY, JUNE 13, 2012

8:30–9:00:Registration and Continental Breakfast
9:00–9:15:Welcoming Remarks and Summary of Day One: David Relman

SESSION III. Application of Genomics and High-Throughput Technologies for Microbial Surveillance and Outbreak Traceback

Claire Fraser, Moderator
9:15–9:45:Virulence as an Emergent Property
Arturo Casadevall, Albert Einstein College of Medicine
9:45–10:15:Understanding the Origins, Evolution, and Transmission Dynamics of Outbreak Agents Through Genomic Epidemiology
Jennifer Gardy, British Columbia Centre for Disease Control/University of British Columbia
10:15–10:45:Use of Genomic Platforms to Detect and Discover Emerging/Evolving Viral Diseases
David Wang, Washington University in St. Louis
10:45–11:00:BREAK
11:00–11:30:Genomic Epidemiology of Gram-Negative Pathogens: From Acinetobacter to E. coli
Mark Pallen, University of Birmingham
11:30–12:00:The Impact of Sequencing Errors on Estimates of Diversity in the Rare Biosphere (and Potential Solutions)
Susan Huse, Marine Biological Laboratory
12:00–12:30:Discussion
12:30–1:15:LUNCH

SESSION IV. Microbial Forensic Tools, Technologies, and Platforms: Problems of Concordance and Discordance

Paul Keim, Moderator
1:15–1:45:Microbial Forensics
Bruce Budowle, University of North Texas Health Science Center
1:45–2:15:Discussion of the Technical Approaches Used in the Amerithrax Investigation
Claire Fraser, University of Maryland Institute for Genome Sciences
2:15–2:45:Analyzing Metagenomic Data: Inferring Microbial Community Function with MG-RAST
Folker Meyer, Argonne National Laboratory
2:45–3:00:BREAK
3:00–5:00:Panel Discussion: The Problem of Concordance and Discordance in Data Generated Using Different Platforms and Technologies
DISCUSSANTS:
  • George Weinstock
  • Susan Huse
  • Mark Pallen
  • Jack Gilbert
5:00–5:15:Concluding Remarks
5:15:ADJOURN
Copyright © 2013, National Academy of Sciences.
Bookshelf ID: NBK159757

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