The committee would like to acknowledge the many speakers and attendees at its open meeting held on February 9, 2004, at the National Academy of Sciences building in Washington, DC. The discussions were informative and helpful. The committee would also like to thank those people who submitted information to the committee through the mail or via e-mail. Finally, the committee thanks the IOM staff for their dedication to this project. Without their commitment, attention to detail, creativity, sensitivity, and hard work, this project would be unworkable.