Figure 13-41. The formation of clathrin-coated vesicles from the plasma membrane.

Figure 13-41The formation of clathrin-coated vesicles from the plasma membrane

These electron micrographs illustrate the probable sequence of events in the formation of a clathrin-coated vesicle from a clathrin-coated pit. The clathrin-coated pits and vesicles shown are larger than those seen in normal-sized cells. They are involved in taking up lipoprotein particles into a very large hen oocyte to form yolk. The lipoprotein particles bound to their membrane-bound receptors can be seen as a dense, fuzzy layer on the extracellular surface of the plasma membrane—which is the inside surface of the vesicle. (Courtesy of M.M. Perry and A.B. Gilbert, J. Cell Sci. 39:257–272, 1979. © The Company of Biologists.)

From: Transport into the Cell from the Plasma Membrane: Endocytosis

Cover of Molecular Biology of the Cell
Molecular Biology of the Cell. 4th edition.
Alberts B, Johnson A, Lewis J, et al.
New York: Garland Science; 2002.
Copyright © 2002, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, and Peter Walter; Copyright © 1983, 1989, 1994, Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson .

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