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Bookshelf ID: NBK559657PMID: 32697462
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 444811-40-9
Drug Levels and Effects
Summary of Use during Lactation
Radium-223 dichloride is not indicated for use in women and should not be given to nursing mothers. However, if a nursing mother receives radium-223 dichloride, she should permanently discontinue nursing her current infant.[1]
Drug Levels
Radium-223 has a physical half-life of 11.4 days and emits alpha particles with a decay energy of 5.979 MeV upon decay.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Dilsizian V, Metter D, Palestro C, Zanzonico P. Advisory Committee on Medical Uses of Isotopes (ACMUI) Sub-Committee on Nursing Mother Guidelines for the Medical Administration of Radioactive Material. Final report submitted: January 31, 2019. 2019. https://www
.nrc.gov/docs /ML1903/ML19038A498.pdf.
Substance Identification
Substance Name
Radium Ra 223 Chloride
CAS Registry Number
444811-40-9
Drug Class
Breast Feeding
Milk, Human
Antineoplastic Agents
Radiopharmaceuticals
Radionuclides
Radium
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Radium Ra 223 dichloride in castration-resistant prostate cancer.[Drugs Today (Barc). 2013]Radium Ra 223 dichloride in castration-resistant prostate cancer.Joung JY, Ha YS, Kim IY. Drugs Today (Barc). 2013 Aug; 49(8):483-90.
- Radium-223 dichloride bone-targeted alpha particle therapy for hormone-refractory breast cancer metastatic to bone.[Exp Hematol Oncol. 2014]Radium-223 dichloride bone-targeted alpha particle therapy for hormone-refractory breast cancer metastatic to bone.Takalkar A, Adams S, Subbiah V. Exp Hematol Oncol. 2014; 3:23. Epub 2014 Sep 8.
- Can bone scans guide therapy with radium-223 dichloride for prostate cancer bone metastases?[Cancer Manag Res. 2018]Can bone scans guide therapy with radium-223 dichloride for prostate cancer bone metastases?Gayed I, Salama V, Dawood L, Canfield S, Wan D, Cai C, Joseph U, Amato R. Cancer Manag Res. 2018; 10:3317-3324. Epub 2018 Sep 7.
- Review [Radium-223 dichloride in patients with castration-refractory prostate cancer].[Urologe A. 2017]Review [Radium-223 dichloride in patients with castration-refractory prostate cancer].Winter BM, von Rundstedt FC, Grimm MO. Urologe A. 2017 Nov; 56(11):1435-1439.
- Review Radium 223 dichloride for prostate cancer treatment.[Drug Des Devel Ther. 2017]Review Radium 223 dichloride for prostate cancer treatment.Deshayes E, Roumiguie M, Thibault C, Beuzeboc P, Cachin F, Hennequin C, Huglo D, Rozet F, Kassab-Chahmi D, Rebillard X, et al. Drug Des Devel Ther. 2017; 11:2643-2651. Epub 2017 Sep 6.
- Radium Ra 223 Dichloride - Drugs and Lactation Database (LactMed®)Radium Ra 223 Dichloride - Drugs and Lactation Database (LactMed®)
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