Copyright Notice
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK563398PMID: 33104321
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 738606-46-7
Drug Levels and Effects
Summary of Use during Lactation
No relevant published information exists on the use of bempedoic acid during breastfeeding. Bempedoic acid and its metabolites are 99% plasma protein bound, so amounts in milk are likely very low. However, because of a concern with disruption of infant lipid metabolism, bempedoic acid is best avoided during breastfeeding. An alternate drug is preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Substance Identification
Substance Name
Bempedoic acid
CAS Registry Number
738606-46-7
Drug Class
Breast Feeding
Milk, Human
Anticholesteremic Agents
Antilipemic Agents
Hypolipidemic Agents
Enzyme Inhibitors
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- Review Bempedoic Acid: First Approval.[Drugs. 2020]Review Bempedoic Acid: First Approval.Markham A. Drugs. 2020 May; 80(7):747-753.
- Review Bempedoic Acid: A New Tool in the Battle Against Hyperlipidemia.[Clin Ther. 2021]Review Bempedoic Acid: A New Tool in the Battle Against Hyperlipidemia.Powell J, Piszczatoski C. Clin Ther. 2021 Feb; 43(2):410-420. Epub 2020 Dec 29.
- In brief: Cardiovascular outcomes with bempedoic acid (Nexletol).[Med Lett Drugs Ther. 2023]In brief: Cardiovascular outcomes with bempedoic acid (Nexletol).. Med Lett Drugs Ther. 2023 Apr 17; 65(1674):62-63.
- Review Pitavastatin.[Drugs and Lactation Database (...]Review Pitavastatin.. Drugs and Lactation Database (LactMed®). 2006
- Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr(-/-) Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.[Arterioscler Thromb Vasc Biol....]Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr(-/-) Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid.Samsoondar JP, Burke AC, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Pinkosky SL, Newton RS, Huff MW. Arterioscler Thromb Vasc Biol. 2017 Apr; 37(4):647-656. Epub 2017 Feb 2.
- Bempedoic Acid - Drugs and Lactation Database (LactMed®)Bempedoic Acid - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...