Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 106-60-5
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of oral aminolevulinic acid during breastfeeding. To minimize exposure of the infant, breastfeeding can be withheld for 24 hours after an oral dose. Breastfeeding is not expected to result in exposure of the child to topical aminolevulinic acid due to negligible systemic absorption. Aminolevulinic acid-induced photodynamic therapy has been used successfully to treat various skin lesions of the nipple. This treatment appeared to preserve nipple anatomy for breastfeeding.[1-3]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Zhou X, Zheng M, Zou Y, et al. 5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report. Photodiagnosis Photodyn Ther. 2021;35:102387. [PubMed: 34107318]
- 2.
- Xu S, Wang X, Xu W, et al. Evaluation of photodynamic therapy of skin cancers with partial differential alpha-aminolevulinic acid. Chin Med J (Engl). 2002;115:1141–5. [PubMed: 12215278]
- 3.
- Ye E, Wang W, Wu Y, et al. Cryotherapy combined with photodynamic therapy for successful treatment of condyloma acuminatum in special sites such as the nipple and the nasal vestibule: A series of two case reports. Photodiagnosis Photodyn Ther 2022:102930. [PubMed: 35644347]
Substance Identification
Substance Name
Aminolevulinic Acid
CAS Registry Number
106-60-5
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Clinical Pharmacokinetics and Safety of a 10% Aminolevulinic Acid Hydrochloride Nanoemulsion Gel (BF-200 ALA) in Photodynamic Therapy of Patients Extensively Affected With Actinic Keratosis: Results of 2 Maximal Usage Pharmacokinetic Trials.[Clin Pharmacol Drug Dev. 2022]Clinical Pharmacokinetics and Safety of a 10% Aminolevulinic Acid Hydrochloride Nanoemulsion Gel (BF-200 ALA) in Photodynamic Therapy of Patients Extensively Affected With Actinic Keratosis: Results of 2 Maximal Usage Pharmacokinetic Trials.Novak B, DuBois J, Chahrour O, Papusha T, Hirt S, Philippi T, Zogel C, Osenberg K, Schmitz B, Lübbert H. Clin Pharmacol Drug Dev. 2022 Apr; 11(4):535-550. Epub 2021 Oct 11.
- Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses.[Skin Therapy Lett. 2001]Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses.Lang K, Schulte KW, Ruzicka T, Fritsch C. Skin Therapy Lett. 2001 Sep; 6(10):1-2, 5.
- Comparison of efficiency of photodynamic diagnostics with topical use of the 3% and 15% aminolevulinic acid in the detection of vulvar lesions.[Photodiagnosis Photodyn Ther. ...]Comparison of efficiency of photodynamic diagnostics with topical use of the 3% and 15% aminolevulinic acid in the detection of vulvar lesions.Maździarz A, Zielińska A, Alkhalayla H, Spiewankiewicz B. Photodiagnosis Photodyn Ther. 2013 Dec; 10(4):422-8. Epub 2013 Apr 29.
- Review Hexaminolevulinate.[Drugs and Lactation Database (...]Review Hexaminolevulinate.. Drugs and Lactation Database (LactMed®). 2006
- Review 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges.[Cancer. 1997]Review 5-Aminolevulinic acid-based photodynamic therapy. Clinical research and future challenges.Peng Q, Warloe T, Berg K, Moan J, Kongshaug M, Giercksky KE, Nesland JM. Cancer. 1997 Jun 15; 79(12):2282-308.
- Aminolevulinic Acid - Drugs and Lactation Database (LactMed®)Aminolevulinic Acid - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...