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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
Drug Levels and Effects
Summary of Use during Lactation
Tinzaparin is no longer available in the US. Although tinzaparin has not been studied, other low molecular weight heparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Tinzaparin is acceptable to use during breastfeeding.[1]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Acenocoumarol, Dalteparin, Enoxaparin, Heparin, Rivaroxaban, Warfarin
References
- 1.
- Bates SM, Rajasekhar A, Middeldorp S, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: Venous thromboembolism in the context of pregnancy. Blood Adv. 2018;2:3317–59. [PMC free article: PMC6258928] [PubMed: 30482767]
Substance Identification
Substance Name
Tinzaparin
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Thromboprophylaxis following caesarean section--a comparison of the antithrombotic properties of three low molecular weight heparins--dalteparin, enoxaparin and tinzaparin.[Thromb Haemost. 2001]Thromboprophylaxis following caesarean section--a comparison of the antithrombotic properties of three low molecular weight heparins--dalteparin, enoxaparin and tinzaparin.Ellison J, Thomson AJ, Conkie JA, McCall F, Walker D, Greer A. Thromb Haemost. 2001 Dec; 86(6):1374-8.
- Structural features of glycol-split low-molecular-weight heparins and their heparin lyase generated fragments.[Anal Bioanal Chem. 2014]Structural features of glycol-split low-molecular-weight heparins and their heparin lyase generated fragments.Alekseeva A, Casu B, Cassinelli G, Guerrini M, Torri G, Naggi A. Anal Bioanal Chem. 2014 Jan; 406(1):249-65. Epub 2013 Nov 20.
- Review Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease.[Cochrane Database Syst Rev. 2015]Review Low-molecular-weight heparins for managing vaso-occlusive crises in people with sickle cell disease.van Zuuren EJ, Fedorowicz Z. Cochrane Database Syst Rev. 2015 Dec 18; 2015(12):CD010155. Epub 2015 Dec 18.
- Haemostasis and Thrombosis: Current Clinical Practice: Low-Molecular-Weight Heparins in The Prophylaxis and Treatment of Thrombo-Embolic Disease.[Hematology. 2000]Haemostasis and Thrombosis: Current Clinical Practice: Low-Molecular-Weight Heparins in The Prophylaxis and Treatment of Thrombo-Embolic Disease.O'Shaughnessy DF. Hematology. 2000; 4(5):373-380.
- Review Low-molecular-weight heparins are essentially the same for treatment and prevention of venous thromboembolism.[Pharmacotherapy. 2001]Review Low-molecular-weight heparins are essentially the same for treatment and prevention of venous thromboembolism.Lopez LM. Pharmacotherapy. 2001 Jun; 21(6 Pt 2):56S-61S; discussion 71S-72S.
- Tinzaparin - Drugs and Lactation Database (LactMed®)Tinzaparin - Drugs and Lactation Database (LactMed®)
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