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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 10041-19-7
Drug Levels and Effects
Summary of Use during Lactation
Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[1]
Drug Levels
Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[2] The diarrhea was most likely caused by the danthron.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Lewis JH, Weingold AB., Committee of FDA-Related Matters American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912–23. [PubMed: 2864852]
- 2.
- Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259–63. [PubMed: 4570522]
Substance Identification
Substance Name
Docusate
CAS Registry Number
10041-19-7
Drug Class
Breast Feeding
Lactation
Gastrointestinal Agents
Laxatives
Surface-Active Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Docusate - Drugs and Lactation Database (LactMed®)Docusate - Drugs and Lactation Database (LactMed®)
- PREDICTED: coiled-coil domain-containing protein 135-like [Danio rerio]PREDICTED: coiled-coil domain-containing protein 135-like [Danio rerio]gi|292628136|ref|XP_683491.4|Protein
- Rab6b RAB6B, member RAS oncogene family [Mus musculus]Rab6b RAB6B, member RAS oncogene family [Mus musculus]Gene ID:270192Gene
- gyg1a glycogenin 1a [Danio rerio]gyg1a glycogenin 1a [Danio rerio]Gene ID:406831Gene
- GLG1 glycogenin glucosyltransferase GLG1 [Saccharomyces cerevisiae S288C]GLG1 glycogenin glucosyltransferase GLG1 [Saccharomyces cerevisiae S288C]Gene ID:853932Gene
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