Copyright Notice
Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK501330PMID: 30000389
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 915-30-0
Drug Levels and Effects
Summary of Use during Lactation
No data exist on the use of diphenoxylate during breastfeeding. One expert panel considers diphenoxylate to be unacceptable during breastfeeding.[1] Based on its chemical and pharmacological similarity to narcotics, occasional small doses of diphenoxylate may be acceptable while breastfeeding an older infant, but alternatives are preferred, especially while nursing a newborn.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
- 1.
- Lewis JH, Weingold AB., Committee of FDA-Related Matters American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912–23. [PubMed: 2864852]
Substance Identification
Substance Name
Diphenoxylate
CAS Registry Number
915-30-0
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Review Piritramide.[Drugs and Lactation Database (...]Review Piritramide.. Drugs and Lactation Database (LactMed®). 2006
- Review Meperidine.[Drugs and Lactation Database (...]Review Meperidine.. Drugs and Lactation Database (LactMed®). 2006
- An X-ray study on the acute action of diphenoxylate on the intestinal motility in volunteers.[Arzneimittelforschung. 1975]An X-ray study on the acute action of diphenoxylate on the intestinal motility in volunteers.Ylitalo P, Svinhufvud U, Anttila P, Laasonen L, Gothoni G. Arzneimittelforschung. 1975 Jul; 25(7):1081-2.
- Review Tranylcypromine.[Drugs and Lactation Database (...]Review Tranylcypromine.. Drugs and Lactation Database (LactMed®). 2006
- Review Pentobarbital.[Drugs and Lactation Database (...]Review Pentobarbital.. Drugs and Lactation Database (LactMed®). 2006
- Diphenoxylate - Drugs and Lactation Database (LactMed®)Diphenoxylate - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...