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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 396-01-0
Drug Levels and Effects
Summary of Use during Lactation
Because there is no published experience with triamterene during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Intense diuresis can suppress lactation;[1,2] however, it is unlikely that triamterene alone is sufficiently potent to cause this effect.
Alternate Drugs to Consider
References
- 1.
- Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;1:1353–4.
- 2.
- Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. PMID: 3858. [PubMed: 3858]
Substance Identification
Substance Name
Triamterene
CAS Registry Number
396-01-0
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- NTP Toxicology and Carcinogenesis Studies of Triamterene (CAS No. 396-01-0) in F344/N Rats and B6C3F1 Mice (Feed Studies).[Natl Toxicol Program Tech Rep ...]NTP Toxicology and Carcinogenesis Studies of Triamterene (CAS No. 396-01-0) in F344/N Rats and B6C3F1 Mice (Feed Studies).National Toxicology Program. Natl Toxicol Program Tech Rep Ser. 1993 Dec; 420:1-367.
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