Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 50-55-5
Drug Levels and Effects
Summary of Use during Lactation
Because no information is available on the use of reserpine during breastfeeding and it might adversely affect the breastfed infant, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Although not well documented, reserpine is said to cause nasal stuffiness and increased tracheobronchial secretions in breastfed infants.[1]
Effects on Lactation and Breastmilk
Reserpine has reportedly caused galactorrhea and has been used to increase breastmilk production, although it is obsolete for this use.[2][3][4]
Alternate Drugs to Consider
References
- 1.
- Knowles JA. Drugs in milk. Pediatr Currents. Ross Laboratories. 1972;21:28-32.
- 2.
- Vaidya RA, Vaidya AB, Van Woert MH et al. Galactorrhea and Parkinson-like syndrome: an adverse effect of alpha-methyldopa. Metabolism. 1970;19(12):1068-70. [PubMed: 4923681]
- 3.
- Mazhbits IA. [Use of reserpine as a lactogenic substance]. Akush Ginekol (Mosk). 1970;46(1):70-2. [PubMed: 5433043]
- 4.
- Somlyo AP, Wayde JD. Abnormal lactation. Report of a case induced by reserpine and a brief review of the subject. J Mt Sinai Hosp N Y. 1960;27(Jan-Feb):5-9. [PubMed: 13832752]
Substance Identification
Substance Name
Reserpine
CAS Registry Number
50-55-5
Drug Class
- Breast Feeding
- Antihypertensive Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
- User and Medical Advice Disclaimer
- Drugs and Lactation Database (LactMed) - Record Format
- LactMed - Database Creation and Peer Review Process
- Fact Sheet. Drugs and Lactation Database (LactMed)
- Drugs and Lactation Database (LactMed) - Glossary
- LactMed Selected References
- Drugs and Lactation Database (LactMed) - About Dietary Supplements
- Breastfeeding Links
- PubChem SubstanceRelated PubChem Substances
- PubMedLinks to PubMed
- Review Dalfampridine.[Drugs and Lactation Database (...]Review Dalfampridine.. Drugs and Lactation Database (LactMed®). 2006
- Determination of individual proton affinities of reserpine from its UV-vis and charge-transfer spectra.[J Phys Chem A. 2008]Determination of individual proton affinities of reserpine from its UV-vis and charge-transfer spectra.Ghosh BC, Deb N, Mukherjee AK. J Phys Chem A. 2008 Jul 31; 112(30):6929-35. Epub 2008 Jul 3.
- Review Medroxyprogesterone Acetate.[Drugs and Lactation Database (...]Review Medroxyprogesterone Acetate.. Drugs and Lactation Database (LactMed®). 2006
- Review Betamethasone.[Drugs and Lactation Database (...]Review Betamethasone.. Drugs and Lactation Database (LactMed®). 2006
- Review Cocaine.[Drugs and Lactation Database (...]Review Cocaine.. Drugs and Lactation Database (LactMed®). 2006
- Reserpine - Drugs and Lactation Database (LactMed®)Reserpine - Drugs and Lactation Database (LactMed®)
Your browsing activity is empty.
Activity recording is turned off.
See more...