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Bookshelf ID: NBK513054PMID: 30000984
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 31036-80-3
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of lofexidine during breastfeeding. Lofexidine is chemically and pharmacologically related to clonidine, which reaches high levels in milk and in the breastfed infant. Although it is not contraindicated during breastfeeding, lofexidine should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Substance Identification
Substance Name
Lofexidine
CAS Registry Number
31036-80-3
Drug Class
- Breast Feeding
- Adrenergic Alpha-2 Receptor Agonists,
- Narcotic Antagonists
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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