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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 58-25-3
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of chlordiazepoxide during breastfeeding. Because the drug and metabolites could accumulate in the breastfed infant, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. If chlordiazepoxide is used, monitor the infant for sedation, poor feeding and poor weight gain.
Drug Levels
Chlordiazepoxide is metabolized to active compounds including demoxepam, desmethylchlordiazepoxide, desmethyldiazepam, and oxazepam. Chlordiazepoxide has a long half-life of 5 to 30 hours, and the half-lives of its metabolites range from 14 to 100 hours.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Chlordiazepoxide
CAS Registry Number
58-25-3
Drug Class
Breast Feeding
Milk, Human
Hypnotics and Sedatives
Anti-Anxiety Agents
Benzodiazepines
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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