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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 19393-08-9
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of (1-14C)-triolein as a diagnostic agent. Breastfeeding does not need to be suspended after administration of (1-14C)-triolein.[1,2]
Drug Levels
Carbon 14 is a low-energy beta emitter with a physical half-life of about 5730 years. (1-14C)-triolein has an effective half-life of 15 hours. Approximately 14% of the injected radioactivity is excreted into breastmilk.[1]
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Leide-Svegborn S, Ahlgren L, Johansson L, et al. Excretion of radionuclides in human breast milk after nuclear medicine examinations. Biokinetic and dosimetric data and recommendations on breastfeeding interruption. Eur J Nucl Med Mol Imaging. 2016;43:808–21. [PubMed: 26732471]
- 2.
- Mattsson S, Johansson L, Leide Svegborn S, et al. Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP. 2015;44(2) Suppl:319–21. [PubMed: 26069086]
Substance Identification
Substance Name
(1-14C)-Triolein
CAS Registry Number
19393-08-9
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- Estimation of 14C-triolein assimilation from postprandial serum radioactivity of 14C.[Scand J Clin Lab Invest. 1983]Estimation of 14C-triolein assimilation from postprandial serum radioactivity of 14C.Pedersen NT. Scand J Clin Lab Invest. 1983 Sep; 43(5):415-20.
- The [14C]-triolein breath test is not valid as a test of fat absorption.[Scand J Clin Lab Invest. 1991]The [14C]-triolein breath test is not valid as a test of fat absorption.Pedersen NT, Jørgensen BB, Rannem T. Scand J Clin Lab Invest. 1991 Dec; 51(8):699-703.
- Estimation of assimilation of simultaneously ingested 14C-triolein and 3H-oleic acid as a test of pancreatic digestive function.[Scand J Gastroenterol. 1984]Estimation of assimilation of simultaneously ingested 14C-triolein and 3H-oleic acid as a test of pancreatic digestive function.Thorsgaard Pedersen N. Scand J Gastroenterol. 1984 Mar; 19(2):161-6.
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- (1-14C)-Triolein - Drugs and Lactation Database (LactMed®)(1-14C)-Triolein - Drugs and Lactation Database (LactMed®)
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