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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 869185-19-3
Drug Levels and Effects
Summary of Use during Lactation
Although no published data exist on the use of umeclidinium during breastfeeding, it produces low systemic maternal serum levels and any drug in breastmilk would not be absorbed by the infant. The risk to the breastfed infant of maternal umeclidinium inhalation is small. Combination products such as Anoro Ellipta are likely to be acceptable for similar reasons.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Substance Identification
Substance Name
Umeclidinium
CAS Registry Number
869185-19-3
Drug Class
Breast Feeding
Milk, Human
Parasympatholytics
Muscarinic Antagonists
Bronchodilator Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.[J Pharmacol Exp Ther. 2013]Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.Salmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, et al. J Pharmacol Exp Ther. 2013 May; 345(2):260-70. Epub 2013 Feb 22.
- Fixed-dose combination of umeclidinium and vilanterol for patients with chronic obstructive pulmonary disease: A systematic review.[Clin Respir J. 2019]Fixed-dose combination of umeclidinium and vilanterol for patients with chronic obstructive pulmonary disease: A systematic review.Ramadan WH, Al Masri S, Rizk J. Clin Respir J. 2019 Nov; 13(11):663-673. Epub 2019 Sep 2.
- Pharmacological characterization of the interaction between umeclidinium and vilanterol in human bronchi.[Eur J Pharmacol. 2017]Pharmacological characterization of the interaction between umeclidinium and vilanterol in human bronchi.Calzetta L, Rogliani P, Facciolo F, Rendina E, Cazzola M, Matera MG. Eur J Pharmacol. 2017 Oct 5; 812:147-154. Epub 2017 Jul 14.
- Umeclidinium - Drugs and Lactation Database (LactMed®)Umeclidinium - Drugs and Lactation Database (LactMed®)
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