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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 77-10-1
Drug Levels and Effects
Summary of Use during Lactation
A single case of phencyclidine use has been reported in which a small amount of phencyclidine was detected in breastmilk over 6 weeks after use of an unknown quantity of the drug. Effects on the breastfed infant are unknown.
Drug Levels
Maternal Levels. A 20-year-old pregnant woman was hospitalized 3 days after having a psychotic reaction after smoking phencyclidine. She was hospitalized and treated initially with intramuscular haloperidol and later with oral chlorpromazine. Thirty-six days later she delivered an infant. A breastmilk sample was obtained 5 days later (presumably 44 days after smoking phencyclidine). Phencyclidine was detected in breast milk at a level of 3.9 mcg/L.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Kaufman KR, Petrucha RA, Pitts FN, Jr, Weekes ME. PCP in amniotic fluid and breast milk: Case report. J Clin Psychiatry 1983;44:269-70. [PubMed: 6863228]
Substance Identification
Substance Name
Phencyclidine
CAS Registry Number
77-10-1
Drug Class
Breast Feeding
Milk, Human
Excitatory Amino Acid Antagonists
Hallucinogens
Street Drugs
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