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Seasonal affective disorder: Do non-drug interventions such as light and vitamin therapy lead to better results? IQWiG Reports – Commission No. HT18-04 [Internet] Cologne (Germany): Institute for Quality and Efficiency in Health Care (IQWiG); 2021 Apr 14.

Cover of Seasonal affective disorder

Seasonal affective disorder: Do non-drug interventions such as light and vitamin therapy lead to better results? IQWiG Reports – Commission No. HT18-04 [Internet]

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Appendix BSearch strategies

B.1. Search strategies for benefit assessment and economic evaluation

B.1.1. Searches in bibliographic databases

1. MEDLINE

Search interface: Ovid
  • Ovid MEDLINE(R) 1946 to January Week 1 2019
  • Ovid MEDLINE(R) Daily Update January 09, 2019

The following filters were adopted:

  • Systematic review: Wong [127] – High specificity strategy
  • RCT: Lefebvre [128] – Cochrane Highly Sensitive Search Strategy for identifying randomized trials in MEDLINE: sensitivity-maximizing version (2008 revision)
  • Economic evaluation: Glanville [129] – Emory University (Grady) filter
#Searches
1seasonal affective disorder/
2seasons/
3depressive disorder/
4depression/
5mood disorders/
6or/3-5
7and/2,6
8((seasonal* or winter*) adj5 (disorder* or mood* or depress*)).ti,ab.
9(winter* and (wellbeing* or (well* adj1 being*))).ti,ab.
10or/1,7-9
11phototherapy/
12light/
13light*.ti,ab.
14phototherap*.ti,ab.
15exp vitamin d/
16(vitamin* adj1 (d or d3)).ti,ab.
17or/11-16
18randomized controlled trial.pt.
19controlled clinical trial.pt.
20(randomized or placebo or randomly or trial or groups).ab.
21drug therapy.fs.
22or/18-21
2322 not (exp animals/ not humans.sh.)
24cochrane database of systematic reviews.jn.
25(search or medline or systematic review).tw.
26meta analysis.pt.
27or/24-26
28(economic$ or cost$).ti.
29cost benefit analysis/
30treatment outcome/ and ec.fs.
31or/28-30
3231 not ((animals/ not humans/) or letter.pt.)
33or/23,27,32
34and/10,17,33
3534 not (comment or editorial).pt.
Search interface: Ovid
  • Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations January 08, 2019
  • Ovid MEDLINE(R) Epub Ahead of Print January 09, 2019
#Searches
1((seasonal* or winter*) and (disorder* or mood* or depress*)).ti,ab.
2(winter* and (wellbeing* or (well* and being*))).ti,ab.
3or/1-2
4light*.ti,ab.
5phototherap*.ti,ab.
6(vitamin* and (d or d3)).ti,ab.
7or/4-6
8(clinical trial* or random* or placebo).ti,ab.
9trial.ti.
10(search or meta analysis or medline or systematic review).ti,ab.
11(economic$ or cost$).ti,ab.
12or/8-11
13and/3,7,12

2. Embase

Search interface: Ovid
  • Embase 1974 to 2019 January 09

The following filters were adopted:

  • Systematic review: Wong [127] – High specificity strategy
  • RCT: Wong [127] – Strategy minimizing difference between sensitivity and specificity
  • Economic evaluation: Glanville [129] – Embase G
#Searches
1seasonal affective disorder/
2exp season/
3circannual rhythm/
4or/2-3
5affective neurosis/
6depression/
7or/5-6
8and/4,7
9((seasonal* or winter*) adj5 (disorder* or mood* or depress*)).ti,ab.
10(winter* and (wellbeing* or (well* adj1 being*))).ti,ab.
11or/1,8-10
12phototherapy/
13exp light/
14simulation*.hw.
15light*.ti,ab.
16phototherap*.ti,ab.
17exp vitamin d/
18(vitamin* adj1 (d or d3)).ti,ab.
19or/12-18
20(random* or double-blind*).tw.
21placebo*.mp.
22(meta analysis or systematic review or medline).tw.
23(cost adj effectiveness).ab.
24(cost adj effectiveness).ti.
25(life adj years).ab.
26(life adj year).ab.
27qaly.ab.
28(cost or costs).ab. and controlled study/
29(cost and costs).ab.
30or/20-29
31and/11,19,30
3231 not medline.cr.
3332 not (exp animal/ not exp human/)
3433 not (conference abstract or conference review or editorial).pt.

3. The Cochrane Library

Search interface: Wiley
  • Cochrane Database of Systematic Reviews Issue 1 of 12, January 2019
  • Cochrane Central Register of Controlled Trials Issue 1 of 12, January 2019
IDSearch
#1[mh ^"seasonal affective disorder"]
#2[mh ^"seasons"]
#3[mh ^"depressive disorder"]
#4[mh ^"depression"]
#5[mh ^"mood disorders"]
#6#3 or #4 or #5
#7#2 and #6
#8((seasonal* or winter*) near/5 (disorder* or mood* or depress*)):ti,ab
#9(winter* and (wellbeing* or (well* near/1 being*))):ti,ab
#10#1 or #7 or #8 or #9
#11[mh ^"phototherapy"]
#12[mh ^"light"]
#13light*:ti,ab
#14phototherap*:ti,ab
#15[mh "vitamin d"]
#16(vitamin* near/1 (d or d3)):ti,ab
#17#11 or #12 or #13 or #14 or #15 or #16
#18#10 and #17 in Cochrane Reviews, Cochrane Protocols
#19#10 and #17 in Trials

4. Health Technology Assessment Database

Search interface: Centre for Reviews and Dissemination
LineSearch
1MeSH DESCRIPTOR Seasonal Affective Disorder
2MeSH DESCRIPTOR Seasons
3((seasonal* OR winter*) AND (disorder* OR mood* OR depress*))
4(winter* AND (wellbeing* OR (well* NEXT being*)))
5#1 OR #2 OR #3 OR #4
6MeSH DESCRIPTOR Phototherapy
7MeSH DESCRIPTOR Light
8(light*)
9(phototherap*)
10MeSH DESCRIPTOR Vitamin D EXPLODE ALL TREES
11((vitamin* NEXT (d OR d3)))
12#6 OR #7 OR #8 OR #9 OR #10 OR #11
13(#5 AND #12) IN HTA

5. PsycINFO

Search interface: Ovid
  • PsycINFO 1806 to December Week 5 2018

The following filters were adopted:

  • Systematic review: Eady [130] – Combination of terms for detecting systematic reviews: best specificity
  • RCT: Eady [130] – Combination of terms for detecting studies of treatment: small drop in specificity with a substantive gain in sensitivity
#Searches
1seasonal affective disorder/
2exp season/
3circannual rhythm/
4or/2-3
5affective neurosis/
6depression/
7or/5-6
8and/4,7
9((seasonal* or winter*) adj5 (disorder* or mood* or depress*)).ti,ab.
10(winter* and (wellbeing* or (well* adj1 being*))).ti,ab.
11or/1,8-10
12phototherapy/
13exp light/
14simulation*.hw.
15light*.ti,ab.
16phototherap*.ti,ab.
17exp vitamin d/
18(vitamin* adj1 (d or d3)).ti,ab.
19or/12-18
20(random* or double-blind*).tw.
21placebo*.mp.
22(meta analysis or systematic review or medline).tw.
23(cost adj effectiveness).ab.
24(cost adj effectiveness).ti.
25(life adj years).ab.
26(life adj year).ab.
27qaly.ab.
28(cost or costs).ab. and controlled study/
29(cost and costs).ab.
30or/20-29
31and/11,19,30
3231 not medline.cr.
3332 not (exp animal/ not exp human/)
3433 not (conference abstract or conference review or editorial).pt.

B.1.2. Searches in study registries

1. ClinicalTrials.gov

Provider: U.S. National Institutes of Health
Search strategy
(seasonal affective disorder OR seasonal mood OR seasonal depression OR winter depression) OR (winter AND (wellbeing OR well being OR well-being)) [DISEASE]

2. EU Clinical Trials Register

Provider: European Medicines Agency
Search strategy
(seasonal affective disorder) OR (seasonal mood) OR (seasonal depression) OR (winter depression) OR (winter AND (wellbeing OR (well being) OR well-being))

3. International Clinical Trials Registry Platform Search Portal

Provider: World Health Organization
Search strategy
seasonal affective disorder OR seasonal mood OR seasonal depression OR winter depression OR winter AND wellbeing OR winter AND well being OR winter AND well-being
© IQWiG (Institute for Quality and Efficiency in Health Care)
Bookshelf ID: NBK569940

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