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IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Polychlorinated Dibenzo-para-dioxins and Polychlorinated Dibenzofurans. Lyon (FR): International Agency for Research on Cancer; 1997. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 69.)
Agent | Degree of evidence of carcinogenicity | Overall evaluation of carcinogenicity to humans | |
Human | Animal | ||
Dibenzo-para-dioxin | ND | ESL | 3 |
Polychlorinated dibenzo-para-dioxins | ND | 3 | |
(other than 2,3,7,8-tetrachlorodibenzodioxin) | |||
2,7-DCDD | I | ||
1,2,3,7,8-PeCDD | I | ||
1,2,3,6,7,8-/1,2,3,7,8,9-HxCDD | L | ||
1,2,3,4,6,7,8-HpCDD | I | ||
Polychlorinated dibenzofurans | I | 3 | |
2,3,7,8-TCDF | I | ||
2,3,4,7,8-PeCDF | L | ||
1,2,3,4,7,8-HxCDF | L | ||
2,3,7,8-Tetrachlorodibenzo-para-dioxin | L | S | 1a |
ND, no adequate data; ESL, evidence suggesting lack of carcinogenicity; S, sufficient evidence; L, limited evidence; I, inadequate evidence; 3, group 3: not classifiable as to its carcinogenicity to humans; 1, group 1: carcinogenic to humans; for definitions of criteria for degrees of evidence and groups, see preamble, pp. 23–27.
- a
Mechanism data taken into account in making the overall evaluation
- SUMMARY OF FINAL EVALUATIONS - Polychlorinated Dibenzo-para-dioxins and Polychlo...SUMMARY OF FINAL EVALUATIONS - Polychlorinated Dibenzo-para-dioxins and Polychlorinated Dibenzofurans
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