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IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Polychlorinated Dibenzo-para-dioxins and Polychlorinated Dibenzofurans. Lyon (FR): International Agency for Research on Cancer; 1997. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 69.)

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Polychlorinated Dibenzo-para-dioxins and Polychlorinated Dibenzofurans.

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IARC MONOGRAPHS ON THE EVALUATION OF CARCINOGENIC RISKS TO HUMANS

Volume 1 Some Inorganic Substances, Chlorinated Hydrocarbons, Aromatic Amines, N-Nitroso Compounds, and Natural Products 1972; 184 pages; ISBN 92 832 1201 0 (out of print)

Volume 2 Some Inorganic and Organometallic Compounds 1973; 181 pages; ISBN 92 832 1202 9 (out of print)

Volume 3 Certain Polycyclic Aromatic Hydrocarbons and Heterocyclic Compounds 1973; 271 pages; ISBN 92 832 1203 7 (out of print)

Volume 4 Some Aromatic Amines, Hydrazine and Related Substances, N-Nitroso Compounds and Miscellaneous Alkylating Agents 1974; 286 pages; ISBN 92 832 1204 5

Volume 5 Some Organochlorine Pesticides 1974; 241 pages; ISBN 92 832 1205 3 (out of print)

Volume 6 Sex Hormones 1974; 243 pages; ISBN 92 832 1206 1 (out of print)

Volume 7 Some Anti-Thyroid and Related Substances, Nitrofurans and Industrial Chemicals 1974; 326 pages; ISBN 92 832 1207 X (out of print)

Volume 8 Some Aromatic Azo Compounds 1975; 357 pages; ISBN 92 832 1208 8

Volume 9 Some Aziridines, N-, S- and O-Mustards and Selenium 1975; 268 pages; ISBN 92 832 1209 6

Volume 10 Some Naturally Occurring Substances 1976; 353 pages; ISBN 92 832 1210 X (out of print)

Volume 11 Cadmium, Nickel, Some Epoxides, Miscellaneous Industrial Chemicals and General Considerations on Volatile Anaesthetics 1976; 306 pages; ISBN 92 832 1211 8 (out of print)

Volume 12 Some Carbamates, Thiocarbamates and Carbazides 1976; 282 pages; ISBN 92 832 1212 6

Volume 13 Some Miscellaneous Pharmaceutical Substances 1977; 255 pages; ISBN 92 832 1213 4

Volume 14 Asbestos 1977; 106 pages; ISBN 92 832 1214 2 (out of print)

Volume 15 Some Fumigants, the Herbicides 2,4-D and 2,4,5-T, Chlorinated Dibenzodioxins and Miscellaneous Industrial Chemicals 1977; 354 pages; ISBN 92 832 1215 0 (out of print)

Volume 16 Some Aromatic Amines and Related Nitro Compounds - Hair Dyes, Colouring Agents and Miscellaneous Industrial Chemicals 1978; 400 pages; ISBN 92 832 1216 9

Volume 17 Some N-Nitroso Compounds 1978; 365 pages; ISBN 92 832 1217 7

Volume 18 Polychlorinated Biphenyls and Polybrominated Biphenyls 1978; 140 pages; ISBN 92 832 1218 5

Volume 19 Some Monomers, Plastics and Synthetic Elastomers, and Acrolein 1979; 513 pages; ISBN 92 832 1219 3 (out of print)

Volume 20 Some Halogenated Hydrocarbons 1979; 609 pages; ISBN 92 832 1220 7 (out of print)

Volume 21 Sex Hormones (II) 1979; 583 pages; ISBN 92 832 1521 4

Volume 22 Some Non-Nutritive Sweetening Agents 1980; 208 pages; ISBN 92 832 1522 2

Volume 23 Some Metals and Metallic Compounds 1980; 438 pages; ISBN 92 832 1523 0 (out of print)

Volume 24 Some Pharmaceutical Drugs 1980; 337 pages; ISBN 92 832 1524 9

Volume 25 Wood, Leather and Some Associated Industries 1981; 412 pages; ISBN 92 832 1525 7

Volume 26 Some Antineoplastic and Immunosuppressive Agents 1981; 411 pages; ISBN 92 832 1526 5

Volume 27 Some Aromatic Amines, Anthraquinones and Nitroso Compounds, and Inorganic Fluorides Used in Drinking Water and Dental Preparations 1982; 341 pages; ISBN 92 832 1527 3

Volume 28 The Rubber Industry 1982; 486 pages; ISBN 92 832 1528 1

Volume 29 Some Industrial Chemicals and Dyestuffs 1982; 416 pages; ISBN 92 832 1529 X

Volume 30 Miscellaneous Pesticides 1983; 424 pages; ISBN 92 832 1530 3

Volume 31 Some Food Additives, Feed Additives and Naturally Occurring Substances 1983; 314 pages; ISBN 92 832 1531 1

Volume 32 Polynuclear Aromatic Compounds, Part 1: Chemical, Environmental and Experimental Data 1983; 477 pages; ISBN 92 832 1532 X

Volume 33 Polynuclear Aromatic Compounds, Part 2: Carbon Blacks, Mineral Oils and Some Nitroarenes 1984; 245 pages; ISBN 92 832 1533 8 (out of print)

Volume 34 Polynuclear Aromatic Compounds, Part 3: Industrial Exposures in Aluminium Production, Coal Gasification, Coke Production, and Iron and Steel Founding 1984; 219 pages; ISBN 92 832 1534 6

Volume 35 Polynuclear Aromatic Compounds: Part 4: Bitumens, Coal-Tars and Derived Products, Shale-Oils and Soots 1985; 271 pages; ISBN 92 832 1535 4

Volume 36 Allyl Compounds, Aldehydes, Epoxides and Peroxides 1985; 369 pages; ISBN 92 832 1536 2

Volume 37 Tobacco Habits Other than Smoking; Betel-Quid and Areca-Nut Chewing; and Some Related Nitrosamines 1985; 291 pages; ISBN 92 832 1537 0

Volume 38 Tobacco Smoking 1986; 421 pages; ISBN 92 832 1538 9

Volume 39 Some Chemicals Used in Plastics and Elastomers 1986; 403 pages; ISBN 92 832 1239 8

Volume 40 Some Naturally Occurring and Synthetic Food Components, Furocoumarins and Ultraviolet Radiation 1986; 444 pages; ISBN 92 832 1240 1

Volume 41 Some Halogenated Hydrocarbons and Pesticide Exposures 1986; 434 pages; ISBN 92 832 1241 X

Volume 42 Silica and Some Silicates 1987; 289 pages; ISBN 92 832 1242 8

Volume 43 Man-Made Mineral Fibres and Radon 1988; 300 pages; ISBN 92 832 1243 6

Volume 44 Alcohol Drinking 1988; 416 pages; ISBN 92 832 1244 4

Volume 45 Occupational Exposures in Petroleum Refining; Crude Oil and Major Petroleum Fuels 1989; 322 pages; ISBN 92 832 1245 2

Volume 46 Diesel and Gasoline Engine Exhausts and Some Nitroarenes 1989; 458 pages; ISBN 92 832 1246 0

Volume 47 Some Organic Solvents, Resin Monomers and Related Compounds, Pigments and Occupational Exposures in Paint Manufacture and Painting 1989; 535 pages; ISBN 92 832 1247 9

Volume 48 Some Flame Retardants and Textile Chemicals, and Exposures in the Textile Manufacturing Industry 1990; 345 pages; ISBN: 92 832 1248 7

Volume 49 Chromium, Nickel and Welding 1990; 677 pages; ISBN: 92 832 1249 5

Volume 50 Some Pharmaceutical Drugs 1990; 415 pages; ISBN: 92 832 1259 9

Volume 51 Coffee, Tea, Mate, Methylxanthines and Methylglyoxal 1991; 513 pages; ISBN: 92 832 1251 7

Volume 52 Chlorinated Drinking-Water; Chlorination By-products; Some other Halogenated Compounds; Cobalt and Cobalt Compounds 1991; 544 pages; ISBN: 92 832 1252 5

Volume 53 Occupational Exposures in Insecticide Application, and Some Pesticides 1991; 612 pages; ISBN 92 832 1253 3

Volume 54 Occupational Exposures to Mists and Vapours from Strong Inorganic Acids; and other Industrial Chemicals 1992; 336 pages; ISBN 92 832 1254 1

Volume 55 Solar and Ultraviolet Radiation 1992; 316 pages; ISBN 92 832 1255 X

Volume 56 Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic Aromatic Amines and Mycotoxins 1993; 600 pages; ISBN 92 832 1256 8

Volume 57 Occupational Exposures of Hairdressers and Barbers and Personal Use of Hair Colourants; Some Hair Dyes, Cosmetic Colourants, Industrial Dyestuffs and Aromatic Amines 1993; 428 pages; ISBN 92 832 1257 6

Volume 58 Beryllium, Cadmium, Mercury and Exposures in the Glass Manufacturing Industry 1994; 444 pages; ISBN 92 832 1258 4

Volume 59 Hepatitis Viruses 1994; 286 pages; ISBN 92 832 1259 2

Volume 60 Some Industrial Chemicals 1994; 560 pages; ISBN 92 832 1260 6

Volume 61 Schistosomes, Liver Flukes and Helicobacter pylori 1994; 280 pages; ISBN 92 832 1261 4

Volume 62 Wood Dusts and Formaldehyde 1995; 405 pages; ISBN 92 832 1262 2

Volume 63 Dry cleaning, Some Chlorinated Solvents and Other Industrial Chemicals 1995; 558 pages; ISBN 92 832 1263 0

Volume 64 Human Papillomaviruses 1995; 409 pages; ISBN 92 832 1264 9

Volume 65 Printing Processes, Printing Inks, Carbon Blacks and Some Nitro Compounds 1996; 578 pages; ISBN 92 832 1265 7

Volume 66 Some Pharmaceutical Drug 1996; 514 pages; ISBN 92 832 1266 5

Volume 67 Human Immunodeficiency Viruses and Human T-cell Lymphotropic Viruses 1996; 424 pages; ISBN 92 832 1267 3

Volume 68 Silica, Some Silicates, Coal Dust and para-Aramid Fibrils 1997; 506 pages; ISBN 92 832 1268 1

Volume 69 Poiychlorinated Dibenzo-para-dioxins and Poiychlorinated Dibenzofurans 1997; 666 pages; ISBN 92 832 1269 X

Volume 70 Epstein-Barr Virus and Kaposi's Sarcoma Herpesvirus/Human Herpesvirus 8 1997; 524 pages; ISBN 92 832 1270 3

Supplements to Monographs

Supplement No. 1 Chemicals and Industrial Processes Associated with Cancer in Humans (IARC Monographs, Volumes 1 to 20) 1979; 71 pages; ISBN 92 832 1404 8 (out of print)

Supplement No. 2 Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal 1980; 426 pages; ISBN 92 832 1404 8

Supplement No. 3 Cross Index of Synonyms and Trade Names in Volumes 1 to 26 1982; 199 pages; ISBN 92 832 1405 6 (out of print)

Supplement No. 4 Chemicals, Industrial Processes and Industries Associated with Cancer in Humans (Volumes 1 to 29) 1982; 292 pages; ISBN 92 832 1407 2 (out of print)

Supplement No. 5 Cross Index of Synonyms and Trade Names in Volumes 1 to 36 1985; 259 pages; ISBN 92 832 1408 0 (out of print)

Supplement No. 6 Genetic and Related Effects: An Updating of Selected IARC Monographs from Volumes 1 to 42 1987; 729 pages; ISBN 92 832 1409 9

Supplement No. 7 Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42 1987; 440 pages; ISBN 92 832 1411 0

Supplement No. 8 Cross Index of Synonyms and Trade Names in Volumes 1 to 46 1989; 346 pages; ISBN 92 832 1417 X

IARC Scientific Publications

No. 1 Liver Cancer 1971; 176 pages; ISBN 0 19 723000 8

No. 2 Oncogenesis and Herpesviruses Edited by P.M. Biggs, G. de Thé and L.N. Payne 1972; 515 pages; ISBN 0 19 723001 6

No. 3 N-Nitroso Compounds: Analysis and Formation Edited by P. Bogovski, R. Preussman and E.A. Walker 1972; 140 pages; ISBN 0 19 723002 4

No. 4 Transplacental Carcinogenesis Edited by L. Tomatis and U. Mohr 1973; 181 pages; ISBN 0 19 723003 2

No. 5/6 Pathology of Tumours in Laboratory Animals. Volume 1: Tumours of the Rat Edited by V.S. Turusov 1973/1976; 533 pages; ISBN 92 8321410 2

No. 7 Host Environment Interactions in the Etiology of Cancer in Man Edited by R. Doll and I. Vodopija 1973; 464 pages; ISBN 0 19 723006 7

No. 8 Biological Effects of Asbestos Edited by P. Bogovski, J.C. Gilson, V. Timbrell and J.C. Wagner 1973; 346 pages; ISBN 0 19 723007 5

No. 9 N-Nitroso Compounds in the Environment Edited by P. Bogovski and E.A. Walker 1974; 243 pages; ISBN 0 19 723008 3 No. 10 Chemical Carcinogenesis Essays Edited by R. Montesano and L. Tomatis 1974; 230 pages; ISBN 0 19 723009 1

No. 11 Oncogenesis and Herpes-viruses II Edited by G. de-Thé, M.A. Epstein and H. zur Hausen 1975; Two volumes, 511 pages and 403 pages; ISBN 0 19 723010 5

No. 12 Screening Tests in Chemical Carcinogenesis Edited by R, Montesano, H. Bartsch and L. Tomatis 1976; 666 pages; ISBN 0 19 723051 2

No. 13 Environmental Pollution and Carcinogenic Risks Edited by C. Rosenfeld and W. Davis 1975; 441 pages; ISBN 0 19 723012 1

No. 14 Environmental N-Nitroso Compounds. Analysis and Formation Edited by E.A. Walker, P. Bogovski and L. Griciute 1976; 512 pages; ISBN 0 19 723013 X

No. 15 Cancer Incidence in Five Continents, Volume III Edited by J.A.H. Waterhouse, C. Muir, P. Correa and J. Powell 1976; 584 pages; ISBN 0 19 723014 8

No. 16 Air Pollution and Cancer in Man Edited by U. Mohr, D. Schmähl and L. Tomatis 1977; 328 pages; ISBN 0 19 723015 6

No. 17 Directory of On-Going Research in Cancer Epidemiology 1977 Edited by C.S. Muir and G. Wagner 1977; 599 pages; ISBN 92 832 1117 0 (out of print)

No. 18 Environmental Carcinogens. Selected Methods of Analysis. Volume 1: Analysis of Volatile Nitrosamines in Food Editor-in-Chief: H. Egan 1978; 212 pages; ISBN 0 19 723017 2

No. 19 Environmental Aspects of N-Nitroso Compounds Edited by EA Walker, M. Castegnaro, L. Griciute and R.E. Lyle 1978; 561 pages; ISBN 0 19 723018 0

No. 20 Nasopharyngeal Carcinoma: Etiology and Control Edited by G. de Thé and Y ito 1978; 606 pages; ISBN 0 19 723019 9

No. 21 Cancer Registration and its Techniques Edited by R. MacLennan, C. Muir, R. Steinitz and A. Winkler 1978; 235 pages; ISBN 0 19 723020 2

No. 22 Environmental Carcinogens: Selected Methods of Analysis. Volume 2: Methods for the Measurement of Vinyl Chloride in Polyvinyl chloride), Air, Water and Foodstuffs Editor-in-Chief: H. Egan 1978; 142 pages; ISBN 0 19 723021 0

No. 23 Pathology of Tumours in Laboratory Animals. Volume If: Tumours of the Mouse Editor-in-Chief: V.S. Turusov 1979; 669 pages; ISBN 0 19 723022 9

No. 24 Oncogenesis and Herpesviruses III Edited by G. de-Thé, W. Henle and F. Rapp 1978; Part I: 580 pages, Part II: 512 pages; ISBN 0 19 723023 7

No. 25 Carcinogenic Risk: Strategies for Intervention Edited by W. Davis and C. Rosenfeld 1979; 280 pages; ISBN 0 19 723025 3

No. 26 Directory of On-going Research in Cancer Epidemiology 1978 Edited by C.S. Muir and G. Wagner 1978; 550 pages; ISBN 0 19 723026 1 (out of print)

No. 27 Molecular and Cellular Aspects of Carcinogen Screening Tests Edited by R. Montesano, H. Bartsch and L. Tomatis 1980; 372 pages; ISBN 0 19 723027 X

No. 28 Directory of On-going Research in Cancer Epidemiology 1979 Edited by C.S. Muir and G. Wagner 1979; 672 pages; ISBN 92 832 1128 6 (out of print)

No. 29 Environmental Carcinogens. Selected Methods of Analysis. Volume 3: Analysis of Polycyclic Aromatic Hydrocarbons in Environmental Samples Editor-in-Chief: H. Egan 1979; 240 pages; ISBN 0 19 723028 8

No. 30 Biological Effects of Mineral Fibres Editor-in-Chief: J.C. Wagner 1980; Two volumes, 494 pages & 513 pages; ISBN 0 19 723030 X

No. 31 N-Nitroso Compounds: Analysis, Formation and Occurrence Edited by E.A. Walker, L. Griciute, M. Castegnaro and M. Börzsönyi 1980; 835 pages; ISBN 0 19 723031 8

No. 32 Statistical Methods in Cancer Research.Volume 1: The Analysis of Case-control Studies By N.E. Breslow and N.E. Day 1980; 338 pages; ISBN 92 832 0132 9

No. 33 Handling Chemical Carcinogens in the Laboratory Edited by R. Montesano, H. Bartsch, E. Boyland, G. Della Porta, L Fishbein, RA Griesemer, A.B. Swan and L Tomatis 1979; 32 pages; ISBN 0 19 723033 4 (out of print)

No. 34 Pathology of Tumours in Laboratory Animals. Volume III: Tumours of the Hamster Editor-in-Chief: V.S. Turusov 1982; 461 pages; ISBN 0 19 723034 2

No. 35 Directory of On-going Research in Cancer Epidemiology 1980 Edited by C.S. Muir and G. Wagner 1980; 660 pages; ISBN 0 19 723035 0 (out of print)

No. 36 Cancer Mortality by Occupation and Social Class 1851–1971 Edited by W.P.D. Logan 1982; 253 pages; ISBN 0 19 723036 9

No. 37 Laboratory Decontamination and Destruction of Anatoxins B1, B2, G1, G2 in Laboratory Wastes Edited by M. Castegnaro, D.C. Hunt, E.B. Sansone, P.L. Schuller, M.G. Siriwardana, G.M. Telling, H.P. van Egmond and E.A. Walker 1980; 56 pages; ISBN 0 19 723037 7

No. 38 Directory of On-going Research in Cancer Epidemiology 1981 Edited by CS. Muir and G. Wagner 1981; 696 pages; ISBN 0 19 723038 5 (out of print)

No. 39 Host Factors in Human Carcinogenesis Edited by H. Bartsch and B. Armstrong 1982; 583 pages; ISBN 019 723039 3

No. 40 Environmental Carcinogens: Selected Methods of Analysis. Volume 4: Some Aromatic Amines and Azo Dyes in the General and Industrial Environment Edited by L. Fishbein, M. Castegnaro, I.K. O'Neill and H. Bartsch 1981; 347 pages; ISBN 0 19 723040 7

No. 41 N-Nitroso Compounds: Occurrence and Biological Effects Edited by H. Bartsch, I.K. O'Neill, M. Castegnaro and M. Okada 982; 755 pages; ISBN 0 19 723041 5

No. 42 Cancer Incidence in Five Continents Volume IV Edited by J. Waterhouse, C. Muir, K. Shanmugaratnam and J. Powell 1982; 811 pages; ISBN 0 19 723042 3

No. 43 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some N-Nitrosamines Edited by M. Castegnaro, G. Eisenbrand, G. Ellen, L. Keefer, D. Klein, E.B. Sansone, D. Spincer, G. Telling and K. Webb 1982; 73 pages; ISBN 0 19 723043 1

No. 44 Environmental Carcinogens: Selected Methods of Analysis. Volume 5: Some Mycotoxins Edited by L Stoloff, M. Castegnaro, P. Scott, I.K. O'Neill and H. Bartsch 1983; 455 pages; ISBN 0 19 723044 X

No. 45 Environmental Carcinogens: Selected Methods of Analysis. Volume 6: N-Nitroso Compounds Edited by R. Preussmann, I.K. O'Neill, G. Eisenbrand, B. Spiegelhaider and H. Bartsch 1983; 508 pages; ISBN 0 19 723045 8

No. 46 Directory of On-going Research in Cancer Epidemiology 1982 Edited by C.S. Muir and G. Wagner 1982; 722 pages; ISBN 0 19 723046 6 (out of print)

No. 47 Cancer Incidence in Singapore 1968–1977 Edited by K. Shanmugaratnam, HP. Lee and N.E. Day 1983; 171 pages; ISBN 0 19 723047 4

No. 48 Cancer Incidence in the USSR (2nd Revised Edition) Edited by N.P. Napalkov, G.F. Tserkovny, V.M. Merabishvili, D.M. Parkin, M. Smans and C.S. Muir 1983; 75 pages; ISBN 0 19 723048 2

No. 49 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Polycyciic Aromatic Hydrocarbons Edited by M. Castegnaro, G. Grimmer, O. Hutzinger, W. Karcher, H. Kunte, M. Lafontaine, H.C. Van der Plas, E.B, Sansone and S.P. Tucker 1983; 87 pages; ISBN 0 19 723049 0

No. 50 Directory of On-going Research in Cancer Epidemiology 1983 Edited by C.S. Muir and G. Wagner 1983; 731 pages; ISBN 0 19 723050 4 (out of print)

No. 51 Modulators of Experimental Carcinogenesis Edited by V, Turusov and R. Montesano 1983; 307 pages; ISBN 0 19 723060 1

No. 52 Second Cancers in Relation to Radiation Treatment for Cervical Cancer: Results of a Cancer Registry Collaboration Edited by N.E. Day and J.C. Boice, Jr 1984; 207 pages; ISBN 0 19 723052 0

No. 53 Nickel in the Human Environment Editor-in-Chief: F.W. Sunderman, Jr 1984; 529 pages; ISBN 0 19 723059 8

No. 54 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Hydrazines Edited by M. Castegnaro, G. Ellen, M. Lafontaine, H.C. van der Plas, E.B. Sansone and S.P. Tucker 1983; 87 pages; ISBN 0 19 723053

No. 55 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some N-Nitrosamides Edited by M. Castegnaro, M. Bernard, L.W. van Broekhoven, D. Fine, R. Massey, E.B. Sansone, P.L.R. Smith, B. Spiegelhalder, A. Stacchini, G. Telling and J.J. Vallon 1984; 66 pages; ISBN 0 19 723054 7

No. 56 Models, Mechanisms and Etiology of Tumour Promotion Edited by M. Börzsönyi, N.E, Day, K. Lapis and H. Yamasaki 1984; 532 pages; ISBN 0 19 723058 X

No. 57 N-Nitroso Compounds: Occurrence, Biological Effects and Relevance to Human Cancer Edited by LK. O'Neill, R.C. von Borstel, C.T. Miller, J. Long and H. Bartsch 1984; 1013 pages; ISBN 0 19 723055 5

No. 58 Age-related Factors in Carcinogenesis Edited by A. Likhachev, V. Anisimov and R. Montesano 1985; 288 pages; ISBN 92 832 1158 8

No. 59 Monitoring Human Exposure to Carcinogenic and Mutagenic Agents Edited by A. Berlin, M. Draper, K. Hemminki and H. Vainio 1984; 457 pages; ISBN 0 19 723056 3

No. 60 Burkitt's Lymphoma: A Human Cancer Model Edited by G. Lenoir, G. O'Conor and C.LM, Olweny 1985; 484 pages; ISBN 0 19 723057 1

No. 61 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Haloethers Edited by M. Castegnaro, M. Alvarez, M. lovu, E.B. Sansone, G.M. Telling and D.T. Williams 1985; 55 pages; ISBN 0 19 723061 X

No. 62 Directory of On-going Research in Cancer Epidemiology 1984 Edited by C.S. Muir and G. Wagner 1984; 717 pages; ISBN 0 19 723062 8 (out of print)

No. 63 Virus-associated Cancers in Africa Edited by A.O. Williams, G.T. O'Conor, G.B. de Thé and C.A. Johnson 1984; 773 pages; ISBN 0 19 723063 6

No. 64 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Aromatic Amines and 4-Nitrobiphenyl Edited by M. Castegnaro, J. Barek, J. Dennis, G. Ellen, M. Klibanov, M. Lafontaine, R. Mitchum, P. van Roosmalen, E.B. Sansone, L.A. Sternson and M. Vahl 1985; 84 pages; ISBN: 92 832 1164 2

No. 65 Interpretation of Negative Epidemiological Evidence for Carcinogenicity Edited by N.J. Wald and R. Doll 1985; 232 pages; ISBN 92 832 1165 0

No. 66 The Role of the Registry in Cancer Control Edited by D.M. Parkin, G. Wagner and C.S. Muir 1985; 152 pages; ISBN 92 832 0166 3

No. 67 Transformation Assay of Established Cell Lines: Mechanisms and Application Edited by T. Kakunaga and H. Yamasaki 1985; 225 pages; ISBN 92 832 1167 7

No. 68 Environmental Carcinogens: Selected Methods of Analysis. Volume 7: Some Volatile Halogenated Hydrocarbons Edited by L Fishbein and I.K. O'Neill 1985; 479 pages; ISBN 92 832 1168 5

No. 69 Directory of On-going Research in Cancer Epidemiology 1985 Edited by C.S. Muir and G. Wagner 1985; 745 pages; ISBN 92 823 1169 3 (out of print)

No. 70 The Role of Cyclic Nucleic Acid Adducts in Carcinogenesis and Mutagenesis Edited by B. Singer and H. Bartsch 1986; 467 pages; ISBN 92 832 1170 7

No. 71 Environmental Carcinogens: Selected Methods of Analysis. Volume 8: Some Metals: As, Be, Cd, Cr, Ni, Pb, Se, Zn Edited by I.K. O'Neill, P. Schuller and L. Fishbein 1986; 485 pages; ISBN 92 832 1171 5

No. 72 Atlas of Cancer in Scotland, 1975–1980: Incidence and Epidemiological Perspective Edited by i. Kemp, P. Boyle, M. Smans and C.S. Muir 1985; 285 pages; ISBN 92 832 1172 3

No. 73 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Antineoplastic Agents Edited by M. Castegnaro, J. Adams, M.A. Armour, J. Barek, J. Benvenuto, C. Confalonieri, U. Goff, G. Telling 1985; 163 pages; ISBN 92 832 1173 1

No. 74 Tobacco: A Major International Health Hazard Edited by D. Zaridze and R. Peto 1986; 324 pages; ISBN 92 832 1174 X

No. 75 Cancer Occurrence in Developing Countries Edited by D.M. Parkin 1986; 339 pages; ISBN 92 832 1175 8

No. 76 Screening for Cancer of the Uterine Cervix Edited by M. Hakama, A.B. Miller and N.E. Day 1986; 315 pages; ISBN 92 832 1176 6

No. 77 Hexachlorobenzene: Proceedings of an International Symposium Edited by C.R. Morris and J.R.P. Cabrai 1986; 668 pages; ISBN 92 832 1177 4

No. 78 Carcinogenicity of Alkylating Cytostatic Drugs Edited by D. Schmähl and J.M. Kaldor 1986; 337 pages; ISBN 92 832 1178 2

No. 79 Statistical Methods in Cancer Research. Volume III: The Design and Analysis of Long-term Animal Experiments By J.J. Gart, D. Krewski, P.N. Lee, R.E. Tarone and J. Wahrendorf 1986; 213 pages; ISBN 92 832 1179 0

No, 80 Directory of On-going Research in Cancer Epidemiology 1986 Edited by C.S. Muir and G. Wagner 1986; 805 pages; ISBN 92 832 1180 4 (out of print)

No. 81 Environmental Carcinogens: Methods of Analysis and Exposure Measurement Volume 9: Passive Smoking Edited by I.K. O'Neill, K.D. Brunnemann, B. Dodet and D, Hoffmann 1987; 383 pages; ISBN 92 832 1181 2

No. 82 Statistical Methods in Cancer Research. Volume II: The Design and Analysis of Cohort Studies By N.E. Breslow and N.E. Day 1987; 404 pages; ISBN 92 832 0182 5

No. 83 Long-term and Short-term Assays for Carcinogens: A Critical Appraisal Edited by R. Montesano, H. Bartsch, H. Vainio, J. Wilbourn and H. Yamasaki 1986; 575 pages; ISBN 92 832 1183 9

No. 84 The Relevance of N-Nitroso Compounds to Human Cancer: Exposure and Mechanisms Edited by H. Bartsch, I.K. O'Neill and R. Schulte-Hermann 1987; 671 pages; ISBN 92 832 1184 7

No. 85 Environmental Carcinogens: Methods of Analysis and Exposure Measurement. Volume 10: Benzene and Alkylated Benzenes Edited by L. Fishbein and I.K. O'Neill 1988; 327 pages; ISBN 92 832 1185 5

No. 86 Directory of On-going Research in Cancer Epidemiology 1987 Edited by D.M. Parkin and J. Wahrendorf 1987; 685 pages; ISBN: 92 832 1186 3 (out of print)

No. 87 International Incidence of Childhood Cancer Edited by D.M. Parkin, C.A. Stiller, C.A. Bieber, G.J. Draper. B. Terracini and J.L. Young 1988; 401 page; ISBN 92 832 1187 1 (out of print)

No. 88 Cancer Incidence in Five Continents, Volume V Edited by C. Muir, J. Waterhouse, T. Mack, J. Powell and S. Whelan 1987; 1004 pages; ISBN 92 832 1188 X

No. 89 Methods for Detecting DNA Damaging Agents in Humans: Applications in Cancer Epidemiology and Prevention Edited by H. Bartsch, K. Hemminki and I.K. O'Neill 1988; 518 pages; ISBN 92 832 1189 8 (out of print)

No. 90 Non-occupational Exposure to Mineral Fibres Edited by J. Bignon, J. Peto and R. Saracci 1989; 500 pages; ISBN 92 832 1190 1

No. 91 Trends in Cancer Incidence in Singapore 1968–1982 Edited by H.P. Lee, N.E. Day and K. Shanmugaratnam 1988; 160 pages; ISBN 92 832 1191 X

No. 92 Cell Differentiation, Genes and Cancer Edited by T. Kakunaga, T. Sugimura, L. Tomatis and H. Yamasaki 1988; 204 pages; ISBN 92 832 1192 8

No. 93 Directory of On-going Research in Cancer Epidemiology 1988 Edited by M. Coleman and J. Wahrendorf 1988; 662 pages; ISBN 92 832 1193 6 (out of print)

No. 94 Human Papillomavirus and Cervical Cancer Edited by N. Muñoz, EX. Bosch and O.M. Jensen 1989; 154 pages; ISBN 92 832 1194 4

No. 95 Cancer Registration: Principles and Methods Edited by O.M. Jensen, D.M. Parkin, R. MacLennan, C.S. Muir and R. Skeet 1991; 296 pages; ISBN 92 832 1195 2

No. 96 Perinatal and Multigeneration Carcinogenesis Edited by N.P. Napaikov, J.M. Rice, L. Tomatis and H. Yamasaki 1989; 436 pages; ISBN 92 832 1196 0

No. 97 Occupational Exposure to Silica and Cancer Risk Edited by L Simonato, A.C. Fletcher, R. Saracci and T. Thomas 1990; 124 pages; ISBN 92 832 1197 9

No. 98 Cancer Incidence in Jewish Migrants to Israel, 1961–1981 Edited by R. Steinitz, D.M. Parkin, J.L. Young, C.A. Bieber and L. Katz 1989; 320 pages; ISBN 92 832 1198 7

No. 99 Pathology of Tumours in Laboratory Animals, Second Edition, Volume 1, Tumours of the Rat Edited by V.S. Turusov and U. Mohr 1990; 740 pages; ISBN 92 832 1199 5 For Volumes 2 and 3 (Tumours of the Mouse and Tumours of the Hamster), see IARC Scientific Publications Nos. 111 and 126.

No. 100 Cancer: Causes, Occurrence and Control Editor-in-Chief: L. Tomatis 1990; 352 pages; ISBN 92 832 0110 8

No. 101 Directory of On-going Research in Cancer Epidemiology 1989–1990 Edited by M. Coleman and J. Wahrendorf 1989; 828 pages; ISBN 92 832 2101 X

No. 102 Patterns of Cancer in Five Continents Edited by S.L. Whelan, D.M. Parkin and E. Masuyer 1990; 160 pages; ISBN 92 832 2102 8

No. 103 Evaluating Effectiveness of Primary Prevention of Cancer Edited by M. Hakama, V. Beral, J.W. Cullen and D.M. Parkin 1990; 206 pages; ISBN 92 832 2103 6

No. 104 Complex Mixtures and Cancer Risk Edited by H. Vainio, M. Sorsa and A.J. McMichaei 1990; 441 pages; ISBN 92 832 2104 4

No. 105 Relevance to Human Cancer of N-Nitroso Compounds, Tobacco Smoke and Mycotoxins Edited by I.K. O'Neill, J. Chen and H. Bartsch 1991 ; 614 pages; ISBN 92 832 2105 2

No. 106 Atlas of Cancer Incidence in the Former German Democratic Republic Edited by W.H. Mehnert, M. Smans, C.S. Muir, M. Möhner and D. Schön 1992; 384 pages; ISBN 92 832 2106 0

No. 107 Atlas of Cancer Mortality in the European Economic Community Edited by M. Smans, C Muir and P. Boyle 1992; 213 pages + 44 coloured maps; ISBN 92 832 2107 9

No. 108 Environmental Carcinogens: Methods of Analysis and Exposure Measurement Volume 11: Polychlorinated Dioxins and Dibenzofurans Edited by C. Rappe, H.R. Buser, B.Dodet and I.K. O'Neill 1991 ; 400 pages; ISBN 92 832 2108 7

No. 109 Environmental Carcinogens: Methods of Analysis and Exposure Measurement. Volume 12: Indoor Air Edited by B. Seifert, H. van de Wiel, B.Dodet and I.K. O'Neill 1993; 385 pages; ISBN 92 832 2109 5

No. 110 Directory of On-going Research in Cancer Epidemiology 1991 Edited by MP. Coleman and J. Wahrendorf 1991 ; 753 pages; ISBN 92 832 2110 9

No. 111 Pathology of Tumours in Laboratory Animals, Second Edition. Volume 2: Tumours of the Mouse Edited by V. Turusov and U. Mohr 1994; 800 pages; ISBN 92 832 2111 1

No. 112 Autopsy in Epidemiology and Medical Research Edited by E. Riboii and M. Delendi 1991; 288 pages; ISBN 92 832 2112 5

No. 113 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Mycotoxins Edited by M. Castegnaro, J. Barek, J.M. Frémy, M. Lafontaine, M. Miraglia, E.B, Sansone and G.M. Telling 1991; 63 pages; ISBN 92 832 2113 3

No. 114 Laboratory Decontamination and Destruction of Carcinogens in Laboratory Wastes: Some Polycyclic Heterocyclic Hydrocarbons Edited by M. Castegnaro, J. Barek, J. Jacob, U. Kirso, M. Lafontaine, E.B. Sansone, G.M. Telling and T. Vu Duc 1991; 50 pages; ISBN 92 832 2114 1

No. 115 Mycotoxins, Endemic Nephropathy and Urinary Tract Tumours Edited by M. Castegnaro, R. Piestina, G. Dirheimer, I.N. Chemozemsky and H. Bartsch 1991; 340 pages; ISBN 92 832 2115 X

No. 116 Mechanisms of Carcinogenesis in Risk Identification Edited by H. Vainio, P. Magee, D. McGregor and A.J. McMichael 1992; 615 pages; ISBN 92 832 2116 8

No. 117 Directory of On-going Research in Cancer Epidemiology 1992 Edited by M. Coleman, E. Demaret and J. Wahrendorf 1992; 773 pages; ISBN 92 832 2117 6

No. 118 Cadmium in the Human Environment: Toxicity and Carcinogenicity Edited by G.F. Nordberg, R.F.M. Herbar and L. Aiessio 1992; 470 pages; ISBN 92 832 2118 4

No. 119 The Epidemiology of Cervical Cancer and Human Papillomavirus Edited by N. Muñoz, F.X. Bosch, K.V. Shah and A. Meheus 1992; 288 pages; ISBN 92 832 2119 2

No. 120 Cancer Incidence in Five Continents, Vol. VI Edited by D.M. Parkin, C.S, Muir, SI. Whelan, Y.T. Gao, J. Feriay and J. Powell 1992; 1020 pages; ISBN 92 832 2120 6

No. 121 Time Trends in Cancer Incidence and Mortality By M. Coleman, J. Estéve, P. Damiecki, A. Arslan and H. Renard 1993; 820 pages; ISBN 92 832 2121 4

No. 122 International Classification of Rodent Tumours. Part I. The Rat Editor-in-Chief: U. Mohr 1992–1996; 10 fascicles of 60–100 pages; ISBN 92 832 2122 2

No. 123 Cancer in Italian Migrant Populations Edited by M. Geddes, D.M. Parkin, M. Khlat, D. Balzi and E. Buiatti 1993; 292 pages; ISBN 92 832 2123 0

No. 124 Postlabelling Methods for the Detection of DNA Damage Edited by D.H. Phillips, M. Castegnaro and H. Bartsch 1993; 392 pages; ISBN 92 832 2124 9

No. 125 DNA Adducts: Identification and Biological Significance Edited by K. Hemminki, A. Dipple, D.E.G. Shuker, F.F. Kadiubar, D. Segerbäck and H. Bartsch 1994; 478 pages; ISBN 92 832 2125 7

No. 126 Pathology of Tumours in Laboratory Animals, Second Edition. Volume 3: Tumours of the Hamster Edited by V. Turosov and U. Mohr 1996; 464 pages; ISBN 92 832 2126 5

No. 127 Butadiene and Styrene: Assessment of Health Hazards Edited by M. Sorsa, K. Peltonen, H. Vainio and K. Hemminki 1993; 412 pages; ISBN 92 832 2127 3

No. 128 Statistical Methods in Cancer Research. Volume IV. Descriptive Epidemiology By J. Estève, E. Benhamou and L. Raymond 1994; 302 pages; ISBN 92 832 2128 1

No. 129 Occupational Cancer in Developing Countries Edited by N. Pearce, E. Matos, H. Vainio, P. Boffetta and M. Kogevinas 1994; 191 pages; ISBN 92 832 2129 X

No. 130 Directory of On-going Research in Cancer Epidemiology 1994 Edited by R. Sankaranarayanan, J. Wahrendorf and E. Démaret 1994; 800 pages; ISBN 92 832 2130 3

No. 132 Survival of Cancer Patients in Europe: The EUROCARE Study Edited by F. Berrino, M. Sant, A. Verdecchia, R. Capocaccia, T. Hakulinen and J. Estève 1995; 463 pages; ISBN 92 832 2132 X

No. 134 Atlas of Cancer Mortality in Central Europe W. Zatonski, J. Estéve, M. Smans, J. Tyczynski and P. Boyle 1996; 300 pages; ISBN 92 832 2134 6

No. 135 Methods for Investigating Localized Clustering of Disease Edited by F.E. Alexander and P. Boyle 1996; 235 pages; ISBN 92 832 2135 4

No. 136 Chemoprevention in Cancer Control Edited by M. Hakama, V. Beral, E. Buiatti, J. Faivre and D.M. Parkin 1996; 160 pages; ISBN 92 832 2136 2

No. 137 Directory of On-going Research in Cancer Epidemiology 1996 Edited by R. Sankaranarayan, J. Warendorf and E. Démaret 1996; 810 pages; ISBN 92 832 2137 0

No. 138 Social Inequalities and Cancer Edited by M. Kogevinas, N. Pearce, M. Susser and P. Boffetta 1997; 412 pages; ISBN 92 832 2138 9

No. 139 Principles of Chemoprevention Edited by B.W. Stewart, D. McGregor and P. Kleihues 1996; 358 pages; ISBN 92 832 2139 7

No. 140 Mechanisms of Fibre Carcinogenesis Edited by A.B. Kane, P. Boffetta, R. Saracci and J.D. Wilbourn 1996; 135 pages; ISBN 92 832 2140 0

No. 142 Application of Biomarkers in Cancer Epidemiology Edited by P. Toniolo, P. Boffetta, D.E.G. Shuker, N. Rothman, B. Hulka and N. Pearce 1997; 318 pages; ISBN 92 832 2142 7

No. 143 Cancer Incidence in Five Continentss Vol VII. Edited by D.M. Parkin, S.L. Whelan, J. Ferlay, L. Raymond & J. Young 1997; 1240 pages; ISBN 92 832 2143 5

IARC Technical Reports

No. 1 Cancer in Costa Rica Edited by R. Sierra, R. Barrantes, G. Munoz Leiva, D.M. Parkin, C.A. Bieber and N. Munoz Calero 1988; 124 pages; ISBN92 832 1412 9

No. 2 SEARCH: A Computer Package to Assist the Statistical Analysis of Case-Control Studies Edited by G.J. Macfarlane, P. Boyle and P. Maisonneuve 1991; 80 pages; ISBN 92 832 1413 7

No. 3 Cancer Registration in the European Economic Community Edited by M.P. Coleman and E. Démaret 1988; 188 pages; ISBN 92 832 1414 5

No. 4 Diet, Hormones and Cancer: Methodological Issues for Prospective Studies Edited by E. Riboli and R. Saracci 1988; 156 pages; ISBN 92 832 1415 3

No. 5 Cancer in the Philippines Edited by A.V. Laudico, D. Esteban and D.M. Parkin 1989; 186 pages; ISBN 92 832 1416 1

No. 6 La genese du Centre international de recherche sur le cancer By R. Sohier and A.G.B. Sutherland 1990,102 pages; ISBN 92 832 1418 8

No. 7 Epidemiologie du cancer dans les pays de langue latine 1990, 292 pages; ISBN 92 832 1419 6

No. 8 Comparative Study of Anti-smoking Legislation in Countries of the European Economic Community By A, J. Sasco, P. Dalla-Vorgia and P. Van der Eist 1992; 82 pages; ISBN: 92 832 1421 8 Etude comparative des Législations de Contrôle du Tabagisme dans les Pays de la Communauté économique europäenne 1995; 82 pages; ISBN 92 832 2402 7

No. 9 Epidemiologie du cancer dans les pays de langue latine 1991; 346 pages; ISBN 92 832 1423 4

No. 10 Manual for Cancer Registry Personnel Edited by D. Esteban, S. Whelan, A. Laudico and D.M. Parkin 1995; 400 pages; ISBN 92 832 1424 2

No. 11 Nitroso Compounds: Biological Mechanisms, Exposures and Cancer Etiology Edited by I. O'Neill and H. Bartsch 1992; 150 pages; ISBN 92 832 1425 X

No. 12 Epidemiologie du cancer dans les pays de langue latine 1992; 375 pages; ISBN 92 832 1426 9

No. 13 Health, Solar UV Radiation and Environmental Change By A. Kricker, B.K.Armstrong, M.E. Jones and R.C. Burton 1993; 213 pages; ISBN 92 832 1427 7

No. 14 Epidemiologie du cancer dans les pays de langue latine 1993; 400 pages; ISBN 92 832 1428 5

No. 15 Cancer in the African Population of Bulawayo, Zimbabwe, 1963–1977 By M.E.G. Skinner, D.M. Parkin, A.P. Vizcaino and A. Ndhiovu 1993; 120 pages; ISBN 92 832 1429 3

No. 16 Cancer in Thailand 1984–1991 By V, Vatanasapt, N. Martin, H. Sriplung, K. Chindavijak, S. Sontipong, S. Sriamporn, D.M. Parkin and J. Ferlay 1993; 164 pages; ISBN 92 832 1430 7

No. 18 Intervention Trials for Cancer Prevention By E. Buiatti 1994; 52 pages; ISBN 92 832 1432 3

No. 19 Comparability and Quality Control in Cancer Registration By D.M. Parkin, V.W. Chen, J. Ferlay, J. Galceran, H.H. Storm and S.L. Whelan 1994; 110 pages plus diskette; ISBN 92 832 1433 1

No. 20 Epidemiologie du cancer dans tes pays de langue latine 1994; 346 pages; ISBN 92 832 1434 X

No. 21 ICD Conversion Programs for Cancer By J. Ferlay 1994; 24 pages plus diskette; ISBN 92 832 1435 8

No. 22 Cancer in Tianjin By Q.S, Wang, P. Boffetta, M. Kogevinas and D.M. Parkin 1994; 96 pages; ISBN 92 832 1433 1

No. 23 An Evaluation Programme for Cancer Preventive Agents By Bernard W. Stewart 1995; 40 pages; ISBN 92 832 1438 2

No. 24 Peroxisome Proliferation and its Role in Carcinogenesis 1995; 85 pages; ISBN 92 832 1439 0

No. 25 Combined Analysis of Cancer Mortality in Nuclear Workers in Canada, the United Kingdom and the United States of America By E. Cardis, E.S. Gilbert, L Carpenter, G. Howe, I. Kato, J. Fix, L Salmon, G. Cowper, B.K. Armstrong, V. Berai, A. Douglas, S.A. Fry, J. Kaldor, C. Lavé, P.G. Smith, G. Voelz and L. Wiggs 1995; 160 pages; ISBN 92 832 1440 4

No. 26 Mortalité par Cancer des Immigrés en France, 1979–1985 By C. Bouchardy, M. Khiat, P. Wanner and D.M. Parkin 1998; 150 pages; ISBN 92 832 2404 3

No. 27 Cancer in Three Generations of Young Israelis: A study of migrants and their descendants By J. Iscovich and D.M. Parkin 1997; 115 pages; ISBN 92 832 1441 2

No. 28 Survey of Cancer Registries in the European Union By H. Storm, I. Ciemmensen and R. Black 1998; 100 pages; ISBN 92 832 1442 0

No. 29 international Classification of Childhood Cancer 1996 By E. Kramarova, C.A. Stiller, J, Ferlay, D.M. Parkin, G.J. Draper, J. Michaelis, J. Neglia and S. Qurechi 1996; 48 pages + diskette; ISBN 92 832 1443 9

No. 30 Cancer Risk from Occupational Exposure to Wood Dust: Pooled Analyses of Epidemiologic Studies Edited by P. Demer and P. Boffetta 1998; 60 pages; ISBN 92 832 1444 7

IARC CancerBases

No. 1 EUCAN90: Cancer in the European Union (Electronic Database with Graphic Display) By J. Ferlay, FU. Black, P. Pisani, M.T. Valdivieso and DM Parkin 1996; Computer software on 3.5” IBM diskette + user's guide (50 pages); ISBN 92 832 1450 1

No. 2 CANINVII: Incidence of Cancer in Five Continents By J. Ferlay 1997; Computer software on 3.5” IBM diskette + user's guide (48 pages); ISBN 92 832 1450 1

All IARC Publications are available directly from IARCPress, 150 Cours Albert Thomas, F-69372 Lyon cedex 08, France (Fax: +33 4 72 73 83 02; E-mail:press@iarc.fr).

IARC Scientific Publications, IARC Handbooks and IARC CancerBases are also available from

Oxford University Press, Walton Street, Oxford, UK OX2 6DP (Fax: +44 1865 267782).

©International Agency for Research on Cancer, 1997.
Bookshelf ID: NBK409966

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