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IARC Working Group on the Evaluation of Cancer-Preventive Interventions. Absence of excess body fatness. Lyon (FR): International Agency for Research on Cancer; 2021. (IARC Handbooks of Cancer Prevention, No. 16.)

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Absence of excess body fatness.

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List of Abbreviations

AKT

protein kinase B

AL

ad libitum

AML

acute myeloid leukaemia

AMP

adenosine monophosphate

AMPK

AMP-activated protein kinase

AOM

azoxymethane

ATP

adenosine triphosphate

BIA

bioelectrical impedance analysis

BMI

body mass index

BOP

N-nitrosobis(2-oxopropyl)amine

CDK

cyclin-dependent kinase

cDNA

complementary DNA

CDR

chronic dietary restriction

CI

confidence interval

CIMP

CpG island methylator phenotype

CLL

chronic lymphocytic leukaemia

CML

chronic myeloid leukaemia

COX-2

cyclooxygenase-2

CR

calorie restriction

CRC

colorectal cancer

CRP

C-reactive protein

CT

computed tomography

DEN

diethylnitrosamine

DHEA

dehydroepiandrosterone

DIO

diet-induced obesity

DLBCL

diffuse large B-cell lymphoma

DMBA

7,12-dimethylbenz[a]anthracene

DR

dietary restriction

DXA

dual-energy X-ray absorptiometry

EDC

endocrine-disrupting chemical

8-epi-PGF

8-epi-prostaglandin F2α

EPIC

European Prospective Investigation into Cancer and Nutrition

ER

estrogen receptor

F344

Fischer 344

GIANT

Genetic Investigation of Anthropometric Traits

GRS

genetic risk score

GTG

gold thioglucose

HBV

hepatitis B virus

HCC

hepatocellular carcinoma

HCV

hepatitis C virus

HER2

human epidermal growth factor receptor 2

HFD

high-fat diet

HPV

human papillomavirus

HR

hazard ratio

HRT

hormone replacement therapy

IARC

International Agency for Research on Cancer

ICD

International Classification of Diseases

IDR

intermittent dietary restriction

IGF-1

insulin-like growth factor 1

IGF-1R

IGF-1 receptor

IGFBP

IGF binding protein

IL

interleukin

IWL

intentional weight loss

LFD

low-fat diet

MAPK

mitogen-activated protein kinase

METs

metabolic equivalents

MMTV

mouse mammary tumour virus

MNU

N-methyl-N-nitrosourea

MRI

magnetic resonance imaging

MSI

microsatellite instability

MSS

microsatellite-stable

mTOR

mammalian target of rapamycin

NAFLD

non-alcoholic fatty liver disease

NAFPD

non-alcoholic fatty pancreatic disease

NASH

non-alcoholic steatohepatitis

NCDs

noncommunicable diseases

NF-κB

nuclear factor kappa-light-chain-enhancer of activated B cells

NHANES

National Health and Nutrition Examination Survey

NHL

non-Hodgkin lymphoma

NIH-AARP

National Institutes of Health–AARP Diet and Health Study

NOS

not otherwise specified

25(OH)D

25-hydroxyvitamin D

OR

odds ratio

8-oxo-dG

8-hydroxydeoxyguanosine

PAI-1

plasminogen activator inhibitor-1

PanIN

pancreatic intraepithelial neoplasia

PCR

polymerase chain reaction

PDAC

pancreatic ductal adenocarcinoma

PI3K

phosphoinositide 3-kinase

PIN

prostatic intraepithelial neoplasia

PPAR

peroxisome proliferator-activated receptor

PR

progesterone receptor

PSA

prostate-specific antigen

RCC

renal cell carcinoma

RCT

randomized controlled trial

ROS

reactive oxygen species

RR

relative risk

SASP

salicylazosulfapyridine

SD

standard deviation

SEER

Surveillance, Epidemiology, and End Results

sGC

soluble guanylyl cyclase

SHBG

sex hormone-binding globulin

SHT

scopolamine hydrobromide trihydrate

SLL

small lymphocytic lymphoma

SNP

single nucleotide polymorphism

STAT

signal transducer and activator of transcription

TDR

total dietary restriction

TGF

transforming growth factor

TNF-α

tumour necrosis factor alpha

TPA

12-O-tetradecanoylphorbol-13-acetate

TRAMP

transgenic adenocarcinoma of the mouse prostate

VEGF

vascular endothelial growth factor

VO2max

maximal oxygen uptake

WC

waist circumference

WCRF

World Cancer Research Fund

WHO

World Health Organization

WHR

waist-to-hip ratio

© International Agency for Research on Cancer, 2021. For more information contact rf.crai@snoitacilbup.
Bookshelf ID: NBK591873

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