Comparative effectiveness research is designed to inform health-care decisions by providing evidence on the effectiveness, benefits, and harms of different treatment options. The evidence is generated from research studies that compare drugs, medical devices, tests, surgeries, or ways to deliver health care.

The Effective Health Care Program funds individual researchers, research centers, and academic organizations to work together with the Agency for Healthcare Research and Quality (AHRQ) to produce effectiveness and comparative effectiveness research for clinicians, consumers, and policymakers.

An important part of comparative effectiveness reviews is to not only synthesize the evidence, but also to identify the gaps in evidence that limited the ability to answer the systematic review questions. Future research needs papers further develop and prioritize the future research needed by decisionmakers.

Contents

• 44. Long-Term Care for Older Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 81
• 43. Strategies To Prevent Weight Gain in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 97
• 42. Treatment Strategies for Women With Coronary Artery Disease: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 66
• 41. Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 58
• 40. Screening for Methicillin-Resistant Staphylococcus aureus (MRSA): Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 102
• 39. Nonoperative and Operative Treatments for Rotator Cuff Tears: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 22
• 38. Treatment for Restless Legs Syndrome: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 86
• 37. Physical Therapy for Knee Pain Secondary to Osteoarthritis: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 77
• 36. Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 72
• 35. Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 103
• 34. Chronic Venous Leg Ulcer Treatment: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 127
• 33. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 83
• 32. Insulin Delivery and Glucose Monitoring Methods: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 57
• 31. Future Research Needs for Childhood Obesity Prevention Programs: Identification of Future Research Needs From Comparative Effectiveness Review No. 115
• 30. Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 99
• 29. Future Research Needs on Procalcitonin-Guided Antibiotic Therapy: Identification of Future Research Needs From Comparative Effectiveness Review No. 78
• 28. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 76
• 27. Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 110
• 26. Pharmacological Management of Crohn's Disease: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 131
• 25. Intravascular Diagnostic Procedures and Imaging Techniques Versus Angiography Alone in Coronary Stenting: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 104
• 24. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 98
• 23. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 73
• 22. Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk Women: Identification of Future Research Needs From Comparative Effectiveness Review No. 80
• 21. Adjuvant Treatment for Phenylketonuria: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 56
• 20. Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders: Identification of Future Research Needs From Comparative Effectiveness Review No. 65
• 19. Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women: Identification of Future Research Needs From Comparative Effectiveness Review No. 41
• 18. Future Research Needs for the Comparative Effectiveness of Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma
• 17. Future Research Needs for Prevention and Treatment of Clostridium difficile Infection: Identification of Future Research Needs From Comparative Effectiveness Review No. 31
• 16. Self-Measured Blood Pressure: Future Research Needs: Identification of Future Research Needs From Comparative Effectiveness Review No. 45
• 15. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda
• 14. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension: Identification of Future Research Needs From Comparative Effectiveness Review No. 34
• 13. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults
• 12. Future Research Needs for Treatment of Obstructive Sleep Apnea: Identification of Future Research Needs From Comparative Effectiveness Review No. 32
• 11. Future Research Needs for Diagnosis of Obstructive Sleep Apnea: Identification of Future Research Needs From Comparative Effectiveness Review No. 32
• 10. Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population: Identification of Future Research Needs From Comparative Effectiveness Review No. 48
• 9. Future Research Needs for Attention Deficit Hyperactivity Disorder: Effectiveness of Treatment in At-Risk Preschoolers; Long-Term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment: Version 2
• 8. Future Research Needs for Angiotensin Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Added to Standard Medical Therapy for Treating Stable Ischemic Heart Disease: Identification of Future Research Needs from Comparative Effectiveness Review No. 18
• 7. Future Research Needs for the Management of Gestational Diabetes
• 6. Future Research Needs for Outcomes of Weight Gain in Pregnancy
• 5. Future Research Needs To Reduce the Risk of Primary Breast Cancer in Women: Identification of Future Research Needs from Comparative Effectiveness Review No. 17
• 4. Future Research Needs for Comparative Effectiveness of Treatments of Localized Prostate Cancer: Identification of Future Research Needs from Comparative Effectiveness Review No. 13
• 3. Future Research Needs for the Integration of Mental Health/Substance Abuse and Primary Care: Identification of Future Research Needs from Evidence Report/Technology Assessment No. 173
• 2. Future Research Needs for the Treatment of Common Hip Fractures: Identification of Future Research from Evidence Report No. 184
• 1. Future Research Needs for the Comparison of Percutaneous Coronary Interventions with Bypass Graft Surgery in Nonacute Coronary Artery Disease: Identification of Future Research Needs from Comparative Effectiveness Review No. 9