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Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology [Internet]. 4th edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.

Cover of Essentials of Glycobiology

Essentials of Glycobiology [Internet]. 4th edition.

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Abbreviations

2-AA

2-aminobenzoic acid

AA

amino acid

AAL

Aleuria aurantia lectin

2-AB

2-aminobenzamide

ABC

ATP-binding cassette

ACE

affinity co-electrophoresis OR angiotensin-converting enzyme

ACG-IB

achrondrogenesis type IB

AchE

acetylcholinesterase

AD

Alzheimer's disease

ADAMTS

a disintegrin and metalloproteinase with thrombospondin motifs

ADCC

antibody-dependent cellular cytotoxicity

ADPKD

autosomal-dominant polycystic kidney disease

AEP

aminoethylphosphonate

AFM

atomic force microscopy

AG

arabinogalactan

AGA

automated glycan assembly

AGEs

advanced glycation end products

AGP

arabinogalactan protein

AGX

arabinoglucuronoxylan

AH

actinohivin

AHM

anhydromannitol

ALG

Asn-linked glycosylation

α-DG

α-dystroglycan

ALS

amyotrophic lateral sclerosis

AMR

Ashwell–Morell receptor

ANTS

8-aminonaphthalene-1,3,6-trisulfonic acid

AOII

atelosteogenesis type II

AOX

alcohol oxidase

APAP

arabinoxylan pectin arabinogalactan protein

APC

antigen-presenting cell

Api

apiose

API

application programming interface

APLP

amyloid precursor–like protein

APTS

1-aminopyrene-3,6,8-trisulfonic acid

ASGPR

asialoglycoprotein receptor

AST

arylsulfotransferase

AuNP

gold nanoparticle

AVM

arteriovenous malformation

BCR

B-cell receptor

BCSDB

Bacterial Carbohydrate Structure Database

βCD

β-cyclodextrin

BMP

bone morphogenetic protein OR bis(monoacylglycero)phosphate

BoNT

Botulinum neurotoxin

BSA

bovine serum albumin

CAD

collision-activated dissociation

CASPER

Computer Assisted Spectrum Evaluation of Regular Polysaccharides [program]

CAZy

Carbohydrate-Active Enzymes [database]

CBM

carbohydrate-binding molecule

CCP

complement control protein

CCSD

Complex Carbohydrate Structure Database [aka CarbBank database]

CD

cluster of differentiation

CDG-II

congenital disorders of glycosylation type II

CD-MPR

cation-dependent mannose 6-phosphate receptor

CE

capillary electrophoresis

CEBiP

chitin oligosaccharide elicitor-binding protein

CER

ceramide

CESA

cellulose synthase

CFG

Consortium for Functional Glycomics

CFTR

cystic fibrosis transmembrane conductance regulator

CGD

congenital disorders of glycosylation

CHIME

coloboma, heart defects, ichthyosiform dermatitis, mental retardation, and ear anomalies with hearing loss [syndrome]

CHO

Chinese hamster ovary

CID

collision-induced dissociation

CI-MPR

cation-independent mannose 6-phosphate receptor

CK

creatine kinase

CM

cytoplasmic membrane

CMAH

CMP–Neu5Ac hydroxylase

CMD

congenital muscular dystrophy

CMP

cytidine monophosphate

CMS

congenital myasthemic syndrome

CMV

cytomegalovirus

CN

cellulose nanomaterial

CNS

central nervous system

CNT

carbon nanotube

CNTFR

ciliary neurotrophic factor receptor

CNX

calnexin

COG

conserved oligomeric Golgi

ConA

concanavalin A

COPD

chronic obstructive pulmonary disease

COPI

coat protein I

COSY

coupling correlated spectroscopy

COVID-19

coronavirus disease 2019

CPS

capsular polysaccharide

CRD

carbohydrate-recognition domain OR cross-reacting determinant

CREB

cAMP response element binding

CREG

cellular repressor of E1A-stimulated genes

CRISPR

clustered regularly interspaced short palindromic repeats

CRP

C-reactive protein

crRNA

CRISPR-targeting guide RNA

CRT

calreticulin

cryo-EM

cryo-electron microscopy

CS

chondroitin sulfate OR circumsporozoite

CsA

contact site A

CSDB

Carbohydrate Structure Database

CSL

CBF1/Su(H)/Lag-1

CT

cholera toxin

CTD

carboxy-terminal domain

CTL

C-type lectin

CTLD

C-type lectin domain

CTLF

C-type lectin fold

DAF

decay accelerating factor

DAG

diacylglycerol

DAMP

damage-associated molecular pattern

DANA

2-deoxy-2,3-di-dehydro-N-acetylneuraminic acid

DAP

DNAX activation protein

DBL

Dolichos biflorus lectin

DC

dendritic cell

DCAL

dendritic cell–associated lectin

DC-SIGN

dendritic cell–specific intercellular adhesion molecule-3-grabbing nonintegrin

DDD2

Dowling–Degos disease type 2

DEEP-STD

differential epitope mapping saturation transfer difference

DFT

density functional theory

DGDG

1,2-diacyl-3-O-(α-D-Gal-(1,6)-O-β-Gal)-sn-glycerol OR digalactosyldiacylglycerol

DIC

disseminated intravascular coagulation

DLL

Delta-like ligand

DMAP

DNA methylase-associated protein

DMB

1,2-diamino-4,5-methylenedioxybenzene

Dol-P

dolichol phosphate

Dol-PP

dolichol pyrophosphate

DON

deoxynorleucine OR 6-diazo-5-oxo-L-norleucine

dp

degree of polymerization

D-PDMP

D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol

Dpp

Decapentaplegic

DS

dermatan sulfate

DSA

Datura stramonium agglutinin

DspB

dispersin B

DTD

diastrophic dystrophy

eAChE

erythrocyte acetylcholinesterase

EAE

experimental allergic encephalomyelitis

EBA

erythrocyte-binding antigen

EBI

European Bioinformatics Institute

EBL

erythrocyte-binding-like

EBR1

egg binding receptor 1

EBV

Epstein–Barr virus

EC

Enzyme Commission

ECD

electron capture dissociation

ECM

extracellular matrix

EcorL

Erythrina corallodendron lectin

EDEM

ER degradation-enhancing α-mannosidase I–like protein

EET

enzyme enhancement therapy

EGF

epidermal growth factor

EGT

ecdysteroid glucosyltransferase

EI

electron impact

eIF2

eukaryotic initiation factor 2

EIS

electrochemical impedance spectroscopy

Elf-1

E74-like factor 1

ELISA

enzyme-linked immunoabsorbent assay

EMT

epithelial–mesenchymal transition

ENDO F2

endoglycosidase F2

ENDO H

endoglycosidase H

eNOS

endothelial nitric oxide synthase

EOGT

EGF-specific O-GlcNAc transferase

EPEC

enteropathogenic E. coli

EPG

endopolygalacturonase

E-PHA

erythroagglutining phytohemagglutinin from Phaseolus vulgaris

EPO

erythropoietin

EPS

exopolysaccharide OR extracellular polysaccharide

ER

endoplasmic reticulum

ERAD

endoplasmic reticulum–associated degradation

ERGIC

ER–Golgi intermediate compartment

ERK

extracellular mitogen-regulated protein kinase

ERT

enzyme replacement therapy

ESI

electrospray ionization

ETD

electron transfer dissociation

EtNP

ethanolamine phosphate

EUL

rice Euonymus-related lectin

FAB

fast atom bombardment

FACE

fluorophore-assisted carbohydrate electrophoresis

FAK

focal adhesion kinase

FCMD

Fukuyama congenital muscular dystrophy

f-CNT

functionalized carbon nanotube

FDA

Food and Drug Administration

FET

field-effect transistor

FGE

formylglycine-generating enzyme

FGF

fibroblast growth factor

FGFR

fibroblast growth factor receptor

FHA

filamentous hemagglutinin

FKRP

fukutin-related protein

FKTN

fukutin

FRC

fibroblastic reticular cell

FSH

follicle-stimulating hormone

FSP

fucose sulfate polymer

FT

Fourier transform OR fucosyl- transferase

GABA

γ-aminobutyric acid

GAG

glycosaminoglycan

Gal

galactose

GALE

uridine diphosphate galactose-4-epimerase

GALK

galactokinase

GALNT

polypeptide GalNAc-transferase

GALT

galactose-1-phosphate uridyltransferase

GalT

galactosyltransferase

GARP

glutamic acid/alanine-rich protein

GAS

Group A streptococcus

GBP

glycan-binding protein

GBS

Group B streptococcus OR Guillain–Barré syndrome

GC

gas chromatography

GCS

glycosylceramide synthase

GDNFR-α

glial-cell-[line-]derived neurotrophic factor receptor-α

GFAT

glucosamine:fructose aminotransferase

GFP

green fluorescent protein

GH

glycoside hydrolase [aka glycosidase]

GIPL

glycoinositol phospholipid

Glc

glucose

GlcA

glucuronic acid

GlcNAc

N-acetylglucosamine

GLIC

Glycome Informatics Consortium

GlycO

Glycomics Ontology

GNA

Galanthus nivalis agglutinin

GNE

N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase

GPCR

G protein–coupled receptor

GPI

glycosylphosphatidylinositol

GPI-AP

GPI-anchored protein

GPP

Glycan Pathway Predictor

GRIFIN

galectin-related interfiber protein

GRP

glycan-recognizing probe OR galectin-related protein OR glycan-recognizing protein

GS

glycogen synthase

GSC

germline stem cell

GSK3β

glycogen synthase kinase-3β

GSL

glycosphingolipid

GT

glycosyltransferase

GWAS

genome-wide association study

GXM

glucuronoxylomannan

GXMG

glucuronoxylomannogalactan

HA

hyaluronan OR hemagglutinin

HAPLN

hyaluronan and proteoglycan link protein

HAS

hyaluronan synthase

HAT

histone acetyltransferase

HBHA

heparin-binding hemagglutinin adhesin

HBP

hexosamine biosynthetic pathway

HCD

high-energy collision dissociation

HCELL

hematopoietic cell E-/L-selectin ligand

HDL

high-density lipoprotein

HDX

hydrogen deuterium exchange

HEMPAS

hereditary erythroblastic multinuclearity with positive acidified-serum test

HEV

high endothelial venule

HF

hydrogen fluoride

HG

homogalacturonan

HGF

hepatocyte growth factor

Hh

Hedgehog

HIBM-II

hereditary inclusion body myopathy type II

HIF

hypoxia-inducible factor

HILIC

hydrophilic interaction liquid chromatography

Hint-1

human intelectin 1

HIT

heparin-induced thrombocytopenia

HIV

human immunodeficiency virus

HMBC

heteronuclear multiple-bond correlation

HME

hereditary multiple exocytosis

HMG

high mobility group

HMM

hidden Markov model

HMO

human milk oligosaccharide

HPA

Helix pomatia agglutinin

HPAEC

high-pH anion-exchange chromatography

HPCE

high-performance capillary electrophoresis

HPLC

high-performance liquid chromatography

HPMRS

hyperphosphatasia with mental retardation syndrome

HRGP

hydroxyproline-rich glycoprotein

HRP

horseradish peroxidase

HS

heparan sulfate

HSCT

hematopoietic stem cell therapy

HSQC

heteronuclear single quantum coherence

HSV

herpes simplex virus

HUPO-PSI

Human Proteome Organization-Proteomics Standards Initiative

Hyp

hydroxyproline

IC

intermediate compartment

ICAM

intercellular adhesion molecule

ID

intellectual disability

IDGF

imaginal disc growth factor

IdoA

iduronic acid

IEF

isoelectric focusing

IFN-γ

interferon-γ

IGD

inherited GPI deficiency

IGSF

immunoglobulin superfamily

IL-1

Interleukin-1

IR

insulin receptor OR infrared

IRS

insulin receptor substrate

ITAM

immunoreceptor tyrosine-based activatory motif

ITC

isothermal titration calorimetry

ITI

inter-α-trypsin inhibitor

ITIM

immunoreceptor tyrosine-based inhibitory motif

ITP

idiopathic thrombocytopenic purpura

IUBMB

International Union of Biochemistry and Molecular Biology

IUPAC

International Union of Pure and Applied Chemistry

JAG

Jagged

JCGGDB

Japan Consortium for Glycobiology and Glycotechnology Database

KCF

KEGG Chemical Function

KDN

2-keto-3-deoxy-D-glycero-D-galactonononic acid

KEGG

Kyoto Encyclopedia of Genes and Genomics

KIR

killer cell immunoglobulin-like receptor

KLH

keyhole limpet hemocyanin

KO

KEGG Orthology [database]

KS

keratan sulfate

LAA

Laburnum alpinum agglutinin

LAD

leukocyte adhesion deficiency

LAM

lipoarabinomannan

LAR

leukocyte common antigen-related protein

LC

liquid chromatography

LCA

Lens culinaris agglutinin

LDL

low-density lipoprotein

LDN

LacdiNAc

LDNF

fucosylated LacdiNAc

LecRK

L-type lectin receptor kinase

LERP

lysosomal enzyme receptor protein

Lex

Lewis x

Lev

levulinoyl

LFNG

Lunatic fringe

LIF

leukemia inhibitory factor OR laser-induced fluorescence

LLO

lipid-linked oligosaccharide

LM

lipomannan

LMW

low-molecular-weight

LNP

lectin nucleotide phosphohydrolase

LOS

lipooligosaccharide

LPG

lipophosphoglycan

L-PHA

L-phytohemagglutinin

LPPG

lipopeptidophosphoglycan

L-PROSY

looped, projected spectroscopy

LPS

lipopolysaccharide

LSC

leukemic stem cell

LSL

Lonchocarpus sericeus agglutinin

LSPR

localized surface plasmon resonance

LTA

lipoteichoic acid OR Lotus tetragonolobus agglutinin

LysM

lysozyme motif

mAb

monoclonal antibody

MAG

myelin-associated glycoprotein

MAH

Maackia amurensis hemagglutinin

MAL

Maackia amurensis lectin

MALDI-MS

matrix-assisted laser desorption/ionization mass spectrometry

MALDI-TOF

matrix-assisted laser desorption/ionization time of flight

Man

mannose

MAP

mitogen-activated protein

MAPK

MAP kinase

MASP

MBL-associated serine protease

MBL

mannose-binding lectin

MBP

mannose-binding protein OR major basic protein

MCD

macular corneal dystrophy

MD

molecular dynamics

m-DAP

meso-diaminopimelic acid

MDCK

Madin–Darby canine kidney

MDL

myeloid DAP12-associating lectin

MDO

membrane-derived oligosaccharide

MDP

metallodipeptidase

MEB

muscle–eye–brain disease

MFNG

Manic fringe

MGDG

1,2-diacyl-3-O-(β-D-Gal)-sn-glycerol OR monogalactosyldiacylglycerol

MGL

macrophage galactose-binding lectin

MGUS

monoclonal gammopathy of unknown significance

MHC

major histocompatibility complex

MIAPE

Minimum Information for A Proteomics Experiment [initiative]

MICL

myeloid inhibitory CTL-like receptor

MINCLE

macrophage inducible Ca++-dependent lectin

MIP-1β

macrophage inflammatory protein-1β

MIRAGE

Minimum Information Required for A Glycomics Experiment [initiative]

MM

molecular mechanics

MMDB

Molecular Modeling Database

MN

membranous neuropathy

MND

motor neuron disease

MNP

magnetic nanoparticle

mOGT

mitochondrial OGT

MPL

monophosphoryl lipid A

MPR

M6P receptor

MPS

mucopolysaccharidosis

MR

mannose receptor

MRH

M6P receptor homology OR mannose receptor homologous

MRI

magnetic resonance imaging

mRNA

messenger RNA

MS

mass spectrometry

MSD

multiple sulfatase deficiency

MSP

merozoite surface protein

MTD

major tropism determinant

MTG

mind-the-gap [protein]

MTX

mosquitocidal toxin

4-MU

4-methylumbelliferone

MVB

multivesicular body

MWCNT

multiwalled carbon nanotube

MytiLec

Mytilus galloprovincialis β-trefoil lectin

NAD

nicotinamide adenine dinucleotide

NADPH

nicotinamide adenine dinucleotide phosphate

NCAM

neural cell adhesion molecule

NCBI

National Center for Biotechnology Information

ncOGT

nucleocytoplasmic OGT

Neu

neuraminic acid

NF-κB

nuclear factor-κB

NHS

N-hydroxysuccinimide

NIR

near-infrared

NK

natural killer

NKT

natural killer T

NLR

NOD-like receptor

NLS

nuclear localization sequence

NMJ

neuromuscular junction

NMR

nuclear magnetic resonance

NOD

nucleotide-binding oligomerization domain

NOE

nuclear Overhauser effect

NP

nanoparticle

NSID

nonsyndromic intellectual disability

NulO

nonulosonic acid

ODR-2

odorant response abnormal 2

OGA

O-GlcNAcase

OGT

O-GlcNAc transferase

OMIM

Online Mendelian Inheritance in Man

OPG

osmoregulated periplasmic glucan

O-PS

O-antigen polysaccharide

ORF

open reading frame

OST

oligosaccharyltransferase

OTase

oligosaccharyltransferase

PAD

pulsed amperometric detection

PAH

pulmonary arterial hypertension

PAI-1

plasminogen activator inhibitor-1

PAM

protospacer adjacent motif

PAMP

pathogen-associated molecular pattern

PAP

pulmonary arterial pressure

PAPS

3′-phosphoadenosine-5′-phosphosulfate

PAS

periodic acid–Schiff

PBP

penicillin-binding protein

PC

phosphorylcholine OR polycystin

PcG

Polycomb group

PCLP

podocalyxin-like protein

PCP

polysaccharide copolymerase

PCR

polymerase chain reaction

PCT

pharmacological chaperone therapy

PDB

Protein Data Bank

PDI

protein disulfide isomerase

PDK

phosphatidylinositol-dependent kinase

PDX1

pancreatic and duodenal homeobox 1

PE

phosphoethanolamine

PECAM

platelet endothelial cell adhesion molecule

PEP

phosphoenolpyruvate

PG

phosphoglycan

PGC

porous graphitized carbon

PGIP

polygalacturonase-inhibiting proteins

PGM

phosphoglucomutase

PHAL

phytohemagglutinin L

PHF

paired helical filament

PI

phosphatidylinositol

PI3K

phosphatidylinositol 3-kinase

PILR

paired immunoglobulin-like receptor

PIM

phosphatidylinositol mannoside

PKC

protein kinase C

PLAP

placental alkaline phosphatase

PLC

phospholipase C

PLE

protein-losing enteropathy

PLM

phospholipomannan

PMAA

partially methylated alditol acetate

PMT

protein mannosyltransferase

PNA

peanut agglutinin

PNAG

poly-N-acetylglucosamine

PNGase F

peptide-N-glycosidase F

PNH

paroxysmal nocturnal hemoglobinuria

PNS

peripheral nervous system

POFUT

protein O-fucosyltransferase

POGLUT

protein O-glucosyltransferase

PPG

proteophosphoglycan

PrP

prion protein

PRR

pattern-recognition receptor

PS

phosphatidylserine

PsA

prespore antigen

PSA

Pisum sativum agglutinin OR polysialic acid

PSGL

P-selectin glycoprotein ligand

PSL

Pisum sativum lectin (pea lectin)

PSP

promastigote surface protease

PVD

pulmonary vascular resistance

QCM

quartz crystal microbalance

QD

quantum dot

QM

quantum mechanics

QTOF

quadrupole time of flight

RA

rheumatoid arthritis

RAGE

receptor for advanced glycation end products

RANKL

receptor activator of nuclear factor (NF)-κB ligand

Rb

retinoblastoma

RCA

Ricinus communis agglutinin

RCL

reactive center loop

RDF

Resource Description Framework

rER

rough endoplasmic reticulum

RF

radio frequency

RFNG

Radical fringe

RG

rhamnogalacturonan

RHO

ras homolog

RI

refractive index

RINGS

Resource for Informatics of Glycomes at Soka

RIP

ribosome-inactivating protein

RME

receptor-mediated endocytosis

RNAi

RNA interference

RNA-seq

RNA sequencing

ROE

rotating-frame Overhauser effect

ROS

reactive oxygen species

RPTP

receptor protein tyrosine phosphatase

rRNA

ribosomal RNA

RRV

relative reactivity value

RU

repeating unit OR resonance unit

SAG

surface antigen

SAM

self-assembled monolayer

SAMP

self-associated molecular pattern

SAP

sphingolipid activator protein OR serum amyloid P

SAX

strong anion exchange chromatography

SAXS

small-angle X-ray scattering

SBA

soybean agglutinin

SCD

sickle cell disease

scFv

single-chain variable fragment

SDF-1

stromal cell–derived factor-1

SDS-PAGE

sodium dodecyl sulfate polyacrylamide gel electrophoresis

SEC

size exclusion chromatography

SED

spondyloepimetaphyseal dysplasia

SeviL

Mytilisepta virgata R-type lectin

SHP-1

Src homology region 2 domain–containing phosphatase-1

shRNA

short hairpin RNA

Sia

sialic acid

SiaT

sialyltransferase

SIB

Swiss Institute of Bioinformatics

Siglec

Sia-binding immunoglobulin-like lectin

siRNA

small interfering RNA

SLE

systemic lupus erythematosus

SLex

sialyl-Lewis x

SLRP

small leucine-rich proteoglycan

Sn

sialoadhesin

SNA

Sambucus nigra agglutinin

SNFG

Symbol Nomenclature for Glycans

SNP

single-nucleotide polymorphism

sOGT

short OGT

SPA

single-particle analysis

SPR

surface plasmon resonance

SRT

substrate reduction therapy

SSA

Sambucus sieboldiana lectin

SSEA

stage-specific embryonic antigen

ST

sialyltransferase

STAT5

signal transducer and activator of transcription 5

STD

saturation transfer difference

SVM

support vector machine

SWCNT

single-walled carbon nanotube

tACE

testis angiotensin-converting enzyme

TACE

TNF-α-converting enzyme

TAIR

The Arabidopsis Information Service

TALE

transcription activator–like effector

TALEN

transcription activator–like effector nuclease

TBS

tertbutyldimethylsilyl

TCGA

The Cancer Genome Atlas

TCR

T-cell receptor

T-DNA

transfer DNA

TEM

transmission electron microscopy

TET

ten-eleven translocation

TF

transcription factor

TGF-β

transforming growth factor β

TGN

trans-Golgi network

Th1

T helper 1

TLC

thin-layer chromatography

TLR

Toll-like receptor

TM

transmembrane domain

TMT

tandem mass tag

TNALP

tissue-nonspecific alkaline phosphatase

TNF-α

tumor necrosis factor-α

TOCSY

total correlation spectroscopy

TP

transpeptidase

TPA

tissue plasminogen activator

TPR

tetratricopeptide repeat

Treg

regulatory T cell

trNOE

transferred nuclear Overhauser effect

TS

trans-sialidase

TSG

TNF-α-stimulated gene

TSP

thrombospondin

TSR

thrombospondin type-1 repeat

TS-TEM

ultrathin section transmission electron microscopy

UCH

ubiquitin carboxyhydrolase

UEA

Ulex europaeus agglutinin

UGT or UGGT

UDP-glucose glycoprotein glucosyltransferase

UniLectin3D

a database covering the three-dimensional features of lectins

uPA(R)

urokinase-type plasminogen activator (receptor)

UTI

urinary tract infection

UV-Vis

ultraviolet-visible

VEGF

vascular endothelial growth factor

VIPL

VIP3b-like

VNTR

variable number tandem repeat

VSA

variant surface antigen

VSG

variant surface glycoprotein

VWF

von Willebrand factor

VZV

Varicella zoster virus

WAX

weak anion exchange

WFA

Wisteria floribunda agglutinin

WGA

wheat germ agglutinin

WTA

wall teichoic acid

WWS

Walker–Warburg syndrome

XGA

xylogalacturonan

XLNSID

X-linked nonsyndromic intellectual disability

XPS

X-ray photoelectron spectroscopy

YY1

Yin Yang 1

Copyright © 2022 by the Consortium of Glycobiology Editors, La Jolla, California. Published by Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. All rights reserved.

The content of this book is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported license. To view the terms and conditions of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/

Bookshelf ID: NBK579940

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