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Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017.
Essentials of Glycobiology [Internet]. 3rd edition.
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Table 1
| GPI-anchored protein | |
|---|---|
| Protozoa | |
| Trypanosoma brucei variant surface glycoprotein (VSG) | protective coat |
| Leishmania major promastigote surface protease (PSP) | bound complement degradation |
| Trypanosoma cruzi GPI-anchored mucins | host cell invasion |
| Plasmodium falciparum merozoite surface protein 1 (MSP-1) | erythrocyte invasion |
| Toxoplasma gondii surface antigen 1 (SAG-1) | host cell invasion |
| Entamoeba histolytica GPI proteophosphoglycans | virulence factor |
| Yeast, fungi, slime mold | |
| Saccharomyces cerevisiae α-agglutinin | adhesion molecule |
| Saccharomyces cerevisiae GAS1p | cell-wall biogenesis |
| Aspergillus fumigatus GEL1p | cell-wall biogenesis |
| Candida albicans HWP1 | adhesion molecule |
| Dictyostelium discoideum prespore antigen (PsA) | adhesion molecule |
| Dictyostelium discoideum contact site A (CsA) | adhesion molecule |
| Plants | |
| Pyrus arabinogalactan proteins (AGPs) | cell-wall biogenesis |
| Arabidopsis thaliana metallo and aspartyl proteases | pollen tube development |
| Arabidopsis thaliana β1-3 glucanase | cell-wall biogenesis |
| Animals (nonmammalian) | |
| Schistosoma mansoni gp200 | praziquantel drug target |
| Caenorhabditis elegans odorant response abnormal 2 (ODR-2) | olfaction |
| Torpedo marmorata acetylcholinesterase (AchE) | hydrolase |
| Mammals | |
| Erythrocyte CD59 and decay acceleration factor (DAF) | complement regulation |
| Alkaline phosphatase | cell-surface hydrolase |
| 5′-Nucleotidase | cell-surface hydrolase |
| Renal dipeptidase | cell-surface hydrolase |
| Trehalase | cell-surface hydrolase |
| Neural cell adhesion molecule 120 (NCAM-120)a | adhesion molecule |
| Neural cell adhesion molecule TAG-1 | adhesion molecule |
| CD58a | adhesion molecule |
| FcγIII receptora | Fc receptor |
| Ciliary neurotrophic factor receptor (CNTFR) α subunit | neural receptor |
| Glial-cell-derived neurotrophic factor receptor (GDNFR) α subunit | neural receptor |
| CD14 | lipopolysaccharide receptor |
| Prion protein (PrP) | unknown |
| Glypican family of GPI-anchored proteoglycans | extracellular matrix component |
- a
Examples for which differential mRNA splicing can result in transmembrane and GPI-anchored forms of the same protein.
- Examples of GPI-Anchored Proteins - Essentials of GlycobiologyExamples of GPI-Anchored Proteins - Essentials of Glycobiology
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