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Contents
- ForewordJo McEntyre, Section Chief and David Lipman, Director.
- Foreword from First EditionStuart Kornfeld.
- PrefaceAjit Varki.
- Preface from First EditionAjit Varki, for The Editors.
- Contributors
- Acknowledgments
- Books and Monograph Resources
- Abbreviations
- Part I. General Principles
- 1. Historical Background and OverviewAjit Varki and Nathan Sharon.
- 2. Structural Basis of Glycan DiversityCarolyn R Bertozzi and David Rabuka.
- 3. Cellular Organization of GlycosylationAjit Varki, Jeffrey D Esko, and Karen J Colley.
- 4. Glycosylation PrecursorsHudson H Freeze and Alan D Elbein.
- 5. Glycosyltransferases and Glycan-processing EnzymesJames Rini, Jeffrey Esko, and Ajit Varki.
- 6. Biological Roles of GlycansAjit Varki and John B Lowe.
- 7. A Genomic View of GlycobiologyBernard Henrissat, Avadesha Surolia, and Pamela Stanley.
- 1. Historical Background and Overview
- Part II. Structure and Biosynthesis
- 8. N-GlycansPamela Stanley, Harry Schachter, and Naoyuki Taniguchi.
- 9. O-GalNAc GlycansInka Brockhausen, Harry Schachter, and Pamela Stanley.
- 10. GlycosphingolipidsRonald L Schnaar, Akemi Suzuki, and Pamela Stanley.
- 11. Glycosylphosphatidylinositol AnchorsMichael AJ Ferguson, Taroh Kinoshita, and Gerald W Hart.
- 12. Other Classes of ER/Golgi-derived GlycansHudson H Freeze and Robert S Haltiwanger.
- 13. Structures Common to Different GlycansPamela Stanley and Richard D Cummings.
- 14. Sialic AcidsAjit Varki and Roland Schauer.
- 15. HyaluronanVince Hascall and Jeffrey D Esko.
- 16. Proteoglycans and Sulfated GlycosaminoglycansJeffrey D Esko, Koji Kimata, and Ulf Lindahl.
- 17. Nucleocytoplasmic GlycosylationGerald W Hart and Christopher M West.
- 18. The O-GlcNAc ModificationGerald W Hart and Yoshihiro Akimoto.
- 8. N-Glycans
- Part III. Organismal Diversity
- 19. Evolution of Glycan DiversityAjit Varki, Hudson H Freeze, and Pascal Gagneux.
- 20. Eubacteria and ArchaeaJeffrey D Esko, Tamara L Doering, and Christian RH Raetz.
- 21. FungiRichard D Cummings and Tamara L Doering.
- 22. ViridiplantaeMarilynn E Etzler and Debra Mohnen.
- 23. NematodaRichard D Cummings and Jeffrey D Esko.
- 24. ArthropodaMichael Tiemeyer, Scott B Selleck, and Jeffrey D Esko.
- 25. DeuterostomesHudson H Freeze, Victor D Vacquier, and Jeffrey D Esko.
- 19. Evolution of Glycan Diversity
- Part IV. Glycan-binding Proteins
- 26. Discovery and Classification of Glycan-Binding ProteinsAjit Varki, Marilynn E Etzler, Richard D Cummings, and Jeffrey D Esko.
- 27. Principles of Glycan RecognitionRichard D Cummings and Jeffrey D Esko.
- 28. R-type LectinsRichard D Cummings and Marilynn E Etzler.
- 29. L-type LectinsMarilynn E Etzler, Avadhesha Surolia, and Richard D Cummings.
- 30. P-type LectinsAjit Varki and Stuart Kornfeld.
- 31. C-type LectinsRichard D Cummings and Rodger P McEver.
- 32. I-type LectinsAjit Varki and Paul R Crocker.
- 33. GalectinsRichard D Cummings and Fu-Tong Liu.
- 34. Microbial Lectins: Hemagglutinins, Adhesins, and ToxinsJeffrey D Esko and Nathan Sharon.
- 35. Proteins that Bind Sulfated GlycosaminoglycansJeffrey D Esko and Robert J Linhardt.
- 26. Discovery and Classification of Glycan-Binding Proteins
- Part V. Glycans in Physiology and Disease
- 36. Glycans in Glycoprotein Quality ControlHudson H Freeze, Jeffrey D Esko, and Armando J Parodi.
- 37. Free Glycans as Signaling MoleculesMarilynn E Etzler and Jeffrey D Esko.
- 38. Glycans in Development and Systemic PhysiologyAjit Varki, Hudson H Freeze, and Victor D Vacquier.
- 39. Bacterial and Viral InfectionsVictor Nizet and Jeffrey D Esko.
- 40. Parasitic InfectionsRichard Cummings and Salvatore Turco.
- 41. Genetic Disorders of Glycan DegradationHudson H Freeze.
- 42. Genetic Disorders of GlycosylationHudson H Freeze and Harry Schachter.
- 43. Glycans in Acquired Human DiseasesAjit Varki and Hudson H Freeze.
- 44. Glycosylation Changes in CancerAjit Varki, Reiji Kannagi, and Bryan P Toole.
- 36. Glycans in Glycoprotein Quality Control
- Part VI. Methods and Applications
- 45. Antibodies and Lectins in Glycan AnalysisRichard D Cummings and Marilynn E Etzler.
- 46. Glycosylation Mutants of Cultured CellsJeffrey D Esko and Pamela Stanley.
- 47. Structural Analysis of GlycansBarbara Mulloy, Gerald W Hart, and Pamela Stanley.
- 48. GlycomicsCarolyn R Bertozzi and Ram Sasisekharan.
- 49. Chemical and Enzymatic Synthesis of Glycans and GlycoconjugatesPeter H Seeberger, Nathaniel Finney, David Rabuka, and Carolyn R Bertozzi.
- 50. Chemical Tools for Inhibiting GlycosylationJeffrey D Esko and Carolyn R Bertozzi.
- 51. Glycans in Biotechnology and the Pharmaceutical IndustryCarolyn R Bertozzi, Hudson H Freeze, Ajit Varki, and Jeffrey D Esko.
- 45. Antibodies and Lectins in Glycan Analysis
- Glossary
- Study Guide
- Errata
- Essentials of GlycobiologyEssentials of Glycobiology
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