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Wilt TJ, Shamliyan T, Shaukat A, et al. Management of Chronic Hepatitis B. Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Oct. (Evidence Reports/Technology Assessments, No. 174.)
This publication is provided for historical reference only and the information may be out of date.
Key Question 1 - literature search string
Database: Ovid MEDLINE(R)
| Medical Subject Heading Terms | Number of Retrieved References | |
|---|---|---|
| 1 | Exp Hepatitis B, chronic/ or exp Hepatitis B/ or exp Hepatitis B virus/ | 39,405 |
| 2 | Exp hepatocellular carcinoma | 40,097 |
| 3 | Exp liver failure | 12,710 |
| 4 | Liver cirrhosis.mp. or exp liver cirrhosis | 59,664 |
| 5 | Liver cirrhosis.mp. or exp liver cirrhosis/ | 393,300 |
| 6 | Exp Death/ or death.mp | 366,266 |
| 7 | Exp Survival/ or survival.mp. or exp survival rate | 480,039 |
| 8 | or/2–7 | 1,076,543 |
| 9 | Natural history/ or cohort studies/ or prospective studies/ or longitudinal studies/ or cohort.mp. or prospective.mp. or longitudinal.mp. | 491,684 |
| 10 | 1 and 8 and 9 | 621 |
| 11 | Limit 10 to (humans and English language) | 558 |
Key Questions 2–4 - literature search strings
| Medical Subject Heading Terms | Number of Retrieved References |
|---|---|
| “Hepatitis B, Chronic”[Mesh] NOT review NOT Case Reports Limits: Humans, Journal Article, English, All Adult: 19+ years | 1,525 |
| “Hepatitis B, Chronic”[Mesh] Limits: Publication Date from 1990/01/01 to 2007/12/31, Humans, Journal Article, English, All Adult: 19+ years | 1,778 |
| “Hepatitis B, Chronic”[Mesh] | 4,329 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 182 |
| “Hepatitis B” Limits: Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 712 |
| (“Hepatitis B, Chronic/prevention and control”[Mesh] OR “Hepatitis B, Chronic/therapy”[Mesh]) AND “Epidemiologic studies” [Mesh] Limits: Humans, English, All Adult: 19+ years | 286 |
| (“Hepatitis B, Chronic/prevention and control”[Mesh] OR “Hepatitis B, Chronic/therapy”[Mesh]) Limits: Humans, English, All Adult: 19+ years | 855 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, English, All Adult: 19+ years AND (“Interferons/drug effects”[Mesh] OR “Interferons/metabolism”[Mesh] OR “Interferons/pharmacokinetics”[Mesh] OR “Interferons/pharmacology”[Mesh] OR “Interferons/poisoning”[Mesh] OR “Interferons/therapeutic use”[Mesh]) Limits: Humans, Controlled Clinical Trial, English, All Adult: 19+ years | 14 |
| (“Interferons/drug effects”[Mesh] OR “Interferons/metabolism”[Mesh] OR “Interferons/pharmacokinetics”[Mesh] OR “Interferons/pharmacology”[Mesh] OR “Interferons/poisoning”[Mesh] OR “Interferons/therapeutic use”[Mesh]) Limits: Humans, Controlled Clinical Trial, English, All Adult: 19+ years | 398 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Controlled Clinical Trial, English, All Adult: 19+ years | 35 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Clinical Trial, Phase IV, English, All Adult: 19+ years | 0 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Clinical Trial, Phase III, English, All Adult: 19+ years | 16 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Clinical Trial, Phase I, Clinical Trial, Phase II, English, All Adult: 19+ years | 23 |
| “Hepatitis B, Chronic”[Mesh] Limits: Humans, Clinical Trial, Phase I, English, All Adult: 19+ years | 10 |
| “Adefovir” [Substance Name] AND “hepatitis B” Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 1 |
| “Adefovir” [Substance Name] Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 6 |
| “Entecavir” [Substance Name] AND “hepatitis B” Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 5 |
| “Entecavir” [Substance Name] Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 6 |
| “Telbivudine” [Substance Name] AND “hepatitis B” Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 4 |
| “Telbivudine” [Substance Name] Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 4 |
| “Interferons”[Mesh] AND “hepatitis B” Limits: Entrez Date from 1990/01/01 to 2007/12/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 169 |
| “Hepatitis B, Chronic”[Mesh] AND “Effect Modifiers (Epidemiology)”[Mesh] Limits: Humans, English, All Adult: 19+ years | 1 |
| “Hepatitis B, Chronic” AND “Treatment Outcome”[Mesh] AND “Effect Modifiers (Epidemiology)”[Mesh] Limits: Humans, English, All Adult: 19+ years | 1 |
| “Hepatitis B, Chronic”[Mesh] AND “Treatment Outcome”[Mesh] AND “Effect Modifiers (Epidemiology)”[Mesh] Limits: Humans, English, All Adult: 19+ years | 1 |
| “Epidemiologic studies”[Mesh] AND “Biological Factors”[Mesh] AND (“Hepatitis B, Chronic/prevention and control”[Mesh] OR “Hepatitis B, Chronic/therapy”[Mesh]) Limits: Humans, English, All Adult: 19+ years | 202 |
| “Biological Factors”[Mesh] AND (“Hepatitis B, Chronic/prevention and control”[Mesh] OR “Hepatitis B, Chronic/therapy”[Mesh]) Limits: Humans, English, All Adult: 19+ years | 576 |
| “Disease Progression”[Mesh] AND (“Hepatitis B, Chronic/prevention and control”[Mesh] OR “Hepatitis B, Chronic/therapy”[Mesh]) Limits: Humans, English, All Adult: 19+ years | 17 |
| Update January 7, 2008 | |
| “Hepatitis B, Chronic”[Mesh] Limits: Publication Date from 2007/11/01 to 2008/3/31, Humans, Randomized Controlled Trial, English, All Adult: 19+ years | 3 |
- Appendix A. Exact Search Strings - Management of Chronic Hepatitis BAppendix A. Exact Search Strings - Management of Chronic Hepatitis B
- Tssr13127 AND (alive[prop]) (0)Gene
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