Table 44-2Number of Agents and Curative Treatment for Childhood Acute Lymphoblastic Leukemia (ALL)

Number of Chemotherapeutic Agents
12345678
Year19481954195619601965197419851988
AgentMethotrexateMPPrednisoneVincristineMethotrexatea AdriamycinAsparagineara-C
CR (%)20–4040–9280–95> 95> 95> 95> 95> 95
Cure (%)000155–35557580
a

Intrathecal MTX.

From: Chapter 44, Principles of Dose, Schedule, and Combination Therapy

Cover of Holland-Frei Cancer Medicine
Holland-Frei Cancer Medicine. 6th edition.
Kufe DW, Pollock RE, Weichselbaum RR, et al., editors.
Hamilton (ON): BC Decker; 2003.
Copyright © 2003, BC Decker Inc.

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