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Donahue KE, Gartlehner G, Schulman ER, et al. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Jul. (Comparative Effectiveness Review, No. 211.)

Cover of Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update

Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update [Internet].

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Appendix ASearch Strings

PubMed: April 11, 2017 Original Searches

Results: 1778 imported after removing duplicates

The original search retrieved an original total of 1934 records, and after initial removal of 149 duplicates, 1785 records were left. Further deduplication of seven records left 1778 records for literature review.

SearchQueryItems found
#1Search “arthritis, rheumatoid”[MeSH Terms] OR “rheumatoid arthritis”[All Fields]130439
#2Search (“Adrenal Cortex Hormones”[MeSH] OR corticosteroid*)312282
#3Search (Methylprednisolone OR prednisone OR prednisolone)106322
#4Search (Hydroxychloroquine OR Leflunomide OR Methotrexate OR Sulfasalazine)56751
#5Search (Adalimumab OR “certolizumab pegol” OR etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR Sarilumab OR Baricitinib OR Sirukumab)39136
#6Search (amjevita OR Inflectra OR Erelzi)32
#7Search (#2 OR #3 OR #4 OR #5 OR #6)464392
#8Search (#1 AND #7)23197
#9Search (letter[pt] OR newspaper article[pt] OR editorial[pt] OR comment[pt])1557410
#10Search (#8 NOT #9)21103
#11Search (#8 NOT #9) Filters: English16989
#12Search (#8 NOT #9) Filters: Humans; English14387
#13Search (#8 NOT #9) Filters: Humans; English; Adult: 19+ years9107
#14Search “Randomized Controlled Trial”[Publication Type] OR “Single-Blind Method”[MeSH] OR “Double-Blind Method”[MeSH] OR “Random Allocation”[MeSH] OR ((randomized[title/abstract] OR randomised[title/abstract]) AND controlled[title/abstract] AND trial[title/abstract])581377
#15Search (“review”[Publication Type] AND “systematic”[tiab]) OR “systematic review”[All Fields] OR (“review literature as topic”[MeSH] AND “systematic”[tiab]) OR “meta-analysis”[Publication Type] OR “meta-analysis as topic”[MeSH Terms] OR “meta-analysis”[All Fields]201594
#16Search (“Case-Control Studies”[MeSH] OR “Cohort Studies”[MeSH] OR “Epidemiologic Studies”[MeSH] OR “Cross-Sectional Studies”[MeSH] OR “Organizational Case Studies”[MeSH] OR “Cross-Over Studies”[MeSH] OR “Follow-Up Studies”[MeSH] OR “Seroepidemiologic Studies”[MeSH] OR “Evaluation Studies”[Publication Type] OR “observational study” OR “observational studies”)2247844
#17Search (#13 AND #14)1303
#18Search (#13 AND #15)106
#19Search (#13 AND #16)2867
#20Search (#13 AND #14) Filters: Publication date from 2010/07/01529
#21Search (#13 AND #15) Filters: Publication date from 2010/07/0165
#22Search (#13 AND #16) Filters: Publication date from 2010/07/011340
#23Search (#20 OR #21 OR #22) Filters: Publication date from 2010/07/011785

PubMed: October 5, 2017 Update Searches

Results: 124 imported after removing duplicates

The update search retrieved an original total of 205 records, and after the removal of 81 duplicates, 124 records were left for literature review.

SearchQueryItems found
#1Search “arthritis, rheumatoid”[MeSH Terms] OR “rheumatoid arthritis”[All Fields]132907
#2Search ((“Adrenal Cortex Hormones”[MeSH] OR corticosteroid*))317011
#3Search ((Methylprednisolone OR prednisone OR prednisolone))107804
#4Search ((Hydroxychloroquine OR Leflunomide OR Methotrexate OR Sulfasalazine))57816
#5Search ((Adalimumab OR ïcertolizumab pegolï OR etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR Sarilumab))40963
#6Search ((amjevita OR Inflectra OR Erelzi))37
#7Search (#2 OR #3 OR #4 OR #5 OR #6)472306
#8Search (#1 AND #7)23796
#9Search (letter[pt] OR newspaper article[pt] OR editorial[pt] OR comment[pt])1589852
#10Search (#8 NOT #9)21674
#11Search (#8 NOT #9) Filters: English17534
#12Search (#8 NOT #9) Filters: Humans; English14911
#13Search (#8 NOT #9) Filters: Humans; English; Adult: 19+ years9490
#14Search (“Randomized Controlled Trial”[Publication Type] OR “Single-Blind Method”[MeSH] OR “Double-Blind Method”[MeSH] OR “Random Allocation”[MeSH] OR ((randomized[title/abstract] OR randomised[title/abstract]) AND controlled[title/abstract] AND trial[title/abstract]))599082
#15Search ((“review”[Publication Type] AND “systematic”[tiab]) OR “systematic review”[All Fields] OR (“review literature as topic”[MeSH] AND “systematic”[tiab]) OR “meta-analysis”[Publication Type] OR “meta-analysis as topic”[MeSH Terms] OR “meta-analysis”[All Fields])215879
#16Search (“Case-Control Studies”[MeSH] OR “Cohort Studies”[MeSH] OR “Epidemiologic Studies”[MeSH] OR “Cross-Sectional Studies”[MeSH] OR “Organizational Case Studies”[MeSH] OR “Cross-Over Studies”[MeSH] OR “Follow-Up Studies”[MeSH] OR “Seroepidemiologic Studies”[MeSH] OR “Evaluation Studies”[Publication Type] OR ïobservational studyï OR ïobservational studiesï)2332747
#17Search (#13 AND #14)1393
#18Search (#13 AND #15)116
#19Search (#13 AND #16)3040
#20Search (#13 AND #14) Filters: Publication date from 2016/10/01 to 2017/12/3174
#21Search (#13 AND #15) Filters: Publication date from 2016/10/01 to 2017/12/3110
#22Search (#13 AND #16) Filters: Publication date from 2016/10/01 to 2017/12/31138 (121 imported)

Embase: April 11-12, 2017 Original Searches

Results: 1171 imported after removing duplicates

The original search retrieved an original total of 1413 records, and after initial removal of 101 duplicates, 1312 records were left. Further removal of another 141 duplicates left 1171 records for literature review.

SearchQueryResults
#1‘rheumatoid arthritis’/exp OR ‘rheumatoid arthritis’196,665
#2‘adrenal cortex hormones’ OR corticosteroid*282,225
#3methylprednisolone OR prednisone OR prednisolone320,723
#4hydroxychloroquine OR leflunomide OR methotrexate OR sulfasalazine173,827
#5adalimumab OR ‘certolizumab pegol’ OR etanercept OR golimumab OR infliximab OR abatacept OR tocilizumab OR rituximab OR tofacitinib OR sarilumab OR Baricitinib OR sirukumab115,006
#6amjevita OR inflectra OR erelzi168
#7#2 OR #3 OR #4 OR #5 OR #6703,322
#8#1 AND #756,311
#9#8 AND (‘editorial’/it OR ‘letter’/it)4,240
#10#8 NOT #952,071
#11#10 AND ([adult]/lim OR [aged]/lim OR [middle aged]/lim OR [very elderly]/lim OR [young adult]/lim)17,805
#12#10 AND ([adult]/lim OR [aged]/lim OR [middle aged]/lim OR [very elderly]/lim OR [young adult]/lim) AND [humans]/lim AND [english]/lim15,753
#13‘randomized controlled trial’/exp OR ‘single blind procedure’/exp OR ‘double blind procedure’/exp OR ‘random allocation’/exp540,522
#14‘systematic review’/exp OR ‘systematic review (topic)’/exp OR ‘meta-analysis’/exp OR ‘meta analysis (topic)’/exp OR ‘meta analysis’/exp236,374
#15‘case control study’/exp OR ‘cohort analysis’/exp OR ‘epidemiological study’ OR ‘cross-sectional study’/exp OR ‘organizational case study’ OR ‘crossover procedure’/exp OR ‘seroepidemiologic study’ OR ‘epidemiology’/exp OR ‘multicenter study’/exp OR ‘multicenter study (topic)’/exp OR ‘evaluation research’/exp3,034,615
#16#12 AND #131,426
#17#12 AND #14139
#18#12 AND #154,073
#19#16 AND [2010-2017]/py692
#20#17 AND [2010-2017]/py113
#21#18 AND [2010-2017]/py2,799
#22#19 AND [medline]/lim456
#23#20 AND [medline]/lim45
#24#21 AND [medline]/lim1,659
#25#19 NOT #22236
#26#20 NOT #2368
#27#21 NOT #241,140
#28#25 OR #26 OR #271,312

Embase: October 5, 2017 Update Searches

Results: 280 imported after removing duplicates

The update search retrieved an original total of 356 records, and after initial removal of 21 duplicates, 335 records were left. Further removal of another 55 duplicates left 280 records for literature review.

SearchQueryResults
#1‘rheumatoid arthritis’/exp OR ‘rheumatoid arthritis’201,832
#2‘adrenal cortex hormones’ OR corticosteroid*290,037
#3methylprednisolone OR prednisone OR prednisolone329,261
#4hydroxychloroquine OR leflunomide OR methotrexate OR sulfasalazine178,657
#5adalimumab OR ‘certolizumab pegol’ OR etanercept OR golimumab OR infliximab OR abatacept OR tocilizumab OR rituximab OR tofacitinib OR sarilumab121,123
#6amjevita OR inflectra OR erelzi215
#7#2 OR #3 OR #4 OR #5 OR #6724,071
#8#1 AND #758,100
#9#8 AND (‘editorial’/it OR ‘letter’/it)4,339
#10#8 NOT #953,761
#11#10 AND ([adult]/lim OR [aged]/lim OR [middle aged]/lim OR [very elderly]/lim OR [young adult]/lim)18,752
#12#10 AND ([adult]/lim OR [aged]/lim OR [middle aged]/lim OR [very elderly]/lim OR [young adult]/lim) AND [humans]/lim AND [english]/lim16,684
#13‘randomized controlled trial’/exp OR ‘single blind procedure’/exp OR ‘double blind procedure’/exp OR ‘random allocation’/exp571,238
#14‘systematic review’/exp OR ‘systematic review (topic)’/exp OR ‘meta-analysis’/exp OR ‘meta analysis (topic)’/exp OR ‘meta analysis’/exp257,410
#15‘case control study’/exp OR ‘cohort analysis’/exp OR ‘epidemiological study’ OR ‘cross-sectional study’/exp OR ‘organizational case study’ OR ‘crossover procedure’/exp OR ‘seroepidemiologic study’ OR ‘epidemiology’/exp OR ‘multicenter study’/exp OR ‘multicenter study (topic)’/exp OR ‘evaluation research’/exp3,192,637
#16#12 AND #131,501
#17#12 AND #14149
#18#12 AND #154,459
#19#16 AND 2017:py94
#20#17 AND 2017:py11
#21#18 AND 2017:py464
#22#19 AND [medline]/lim38
#23#20 AND [medline]/lim0
#24#21 AND [medline]/lim148
#25#19 NOT #2256 (27 imported)
#26#20 NOT #2311 (11 imported)
#27#21 NOT #24316 (297 imported)

Cochrane Library: April 12, 2017 Original Searches

Results: 563 imported after removing duplicates

The original search retrieved an original total of 1067 records, and after initial removal of 3 duplicates, 1064 records were left. Further removal of another 501 duplicates left 563 records for literature review.

IDSearchHits
#1[mh “arthritis, rheumatoid”] or “rheumatoid arthritis”9745
#2[mh “Adrenal Cortex Hormones”] or corticosteroid20270
#3Methylprednisolone or prednisone or prednisolone14571
#4Hydroxychloroquine or Leflunomide or Methotrexate or Sulfasalazine8664
#5Adalimumab or “certolizumab pegol” or etanercept or golimumab or infliximab or Abatacept or tocilizumab or rituximab or Tofacitinib or Sarilumab or Baricitinib or Sirukumab6633
#6amjevita or Inflectra or Erelzi8
#7#2 or #3 or #4 or #5 or #641459
#8#1 and #74125
#9“randomized controlled trial”:pt or “randomized controlled trial as topic”:pt or “single-blind method”:pt or “double-blind method”:pt or “random allocation”:pt420356
#10(review and systematic) or “systematic review” or (“review literature as topic” and systematic) or “meta-analysis”63119
#11[mh “Cohort Studies”] or [mh “Epidemiologic Studies”] or [mh “Follow-up Studies”] or “prospective cohort” or [mh “prospective studies”] or (prospective* and cohort and (study or studies))148804
#12#8 and #9 Publication Year from 2010 to 2017700
#13#8 and #10 Publication Year from 2010 to 2017320
#14#8 and #11 Publication Year from 2010 to 2017261
#15#12 or #13 or #141067 (1064 imported)

Cochrane Library: October 5, 2017 Update Searches

Results: 21 imported after removing duplicates

The update search retrieved an original total of 79 records, and after initial removal of one duplicate, 78 records were left. Further removal of another 57 duplicates left 21 records for literature review.

IDSearchHits
#1[mh “arthritis, rheumatoid”] or “rheumatoid arthritis”10184
#2[mh “Adrenal Cortex Hormones”] or corticosteroid21528
#3Methylprednisolone or prednisone or prednisolone15642
#4Hydroxychloroquine or Leflunomide or Methotrexate or Sulfasalazine9289
#5Adalimumab or “certolizumab pegol” or etanercept or golimumab or infliximab or Abatacept or tocilizumab or rituximab or Tofacitinib or Sarilumab7486
#6amjevita or Inflectra or Erelzi11
#7#2 or #3 or #4 or #5 or #644450
#8#1 and #74347
#9“randomized controlled trial”:pt or “randomized controlled trial as topic”:pt or “single-blind method”:pt or “double-blind method”:pt or “random allocation”:pt430710
#10(review and systematic) or “systematic review” or (“review literature as topic” and systematic) or “meta-analysis”64699
#11[mh “Cohort Studies”] or [mh “Epidemiologic Studies”] or [mh “Follow-up Studies”] or “prospective cohort” or [mh “prospective studies”] or (prospective* and cohort and (study or studies))154533
#12#8 and #9 Publication Year from 201745
#13#8 and #10 Publication Year from 201725
#14#8 and #11 Publication Year from 201725
#15#12 or #13 or #1479 (78 imported)

International Pharmaceutical Abstracts: April 12, 2017 Original Searches

Results: 82 imported after removing duplicates

The original search retrieved an original total of 184 records, and after initial removal of 40 duplicates, 144 records were left. Further removal of another 62 duplicates left 82 records for literature review.

#QueryLimiters/ExpandersLast Run ViaResults
S1“rheumatoid arthritis”Search modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4,779
S2“Adrenal Cortex Hormones” OR corticosteroidSearch modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
6,906
S3Methylprednisolone OR prednisone OR prednisoloneSearch modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
6,715
S4Hydroxychloroquine OR Leflunomide OR Methotrexate OR SulfasalazineSearch modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
5,371
S5Adalimumab OR “certolizumab pegol” OR etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR Sarilumab OR Baricitinib OR SirukumabSearch modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4,730
S6amjevita OR Inflectra OR ErelziSearch modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2
S7S2 OR S3 OR S4 OR S5 OR S6Search modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
20,004
S8S1 AND S7Search modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2,493
S9S1 AND S7Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
899
S10S1 AND S7Limiters - Published Date: 20100101-20161231
Narrow by Language: - english
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
878
S11((“Randomized Controlled Trial” OR “Single-Blind Method”OR “Double-Blind Method” OR “Random Allocation” OR ((randomized OR randomised) AND controlled AND trial))Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4,755
S12(“review” AND “systematic”) OR “systematic review” OR “meta-analysis”Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
3,143
S13“Case-Control Studies” OR “Cohort Studies” OR “Epidemiologic Studies” OR “Cross-Sectional Studies” OR “Organizational Case Studies” OR “Cross-Over Studies” OR “Follow-Up Studies” OR “Seroepidemiologic Studies” OR “Evaluation Studies” OR “observational study” OR “observational studies”Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
1,628
S14S10 AND S11Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
85
S15S10 AND S12Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
64
S16S10 AND S13Limiters - Published Date: 20100101-20161231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research
Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
35
S17S14 OR S15 OR S16Search modes - Boolean/PhraseInterface - EBSCOhost Research
Databases
Search Screen - Advanced Search Database - International Pharmaceutical Abstracts
144

International Pharmaceutical Abstracts: October 5, 2017 Update Searches

Results: 0 imported after removing duplicates

The update search retrieved an original total of 11 records, and after the removal of all 11 as duplicates, no records were left for literature review.

#QueryLimiters/ExpandersLast Run ViaResults
S1“rheumatoid arthritis”Search modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4,867
S2“Adrenal Cortex Hormones” OR corticosteroidSearch modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
6,984
S3Methylprednisolone OR prednisone OR prednisoloneSearch modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
6,788
S4Hydroxychloroquine OR Leflunomide OR Methotrexate OR SulfasalazineSearch modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
5,459
S5Adalimumab OR “certolizumab pegol” OR etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR SarilumabSearch modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4,841
S6amjevita OR Inflectra OR ErelziSearch modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
4
S7S2 OR S3 OR S4 OR S5 OR S6Search modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
20,287
S8S1 AND S7Search modes - Boolean/PhraseInterface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2,536
S9S1 AND S7Narrow by Language: - english
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2,427
S10S1 AND S7Limiters - Published Date: 20170101-20171231
Narrow by Language: - english
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
36
S11((“Randomized Controlled Trial” OR “Single-Blind Method”OR “Double-Blind Method” OR “Random Allocation” OR ((randomized OR randomised) AND controlled AND trial))Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
202
S12(“review” AND “systematic”) OR “systematic review” OR “meta-analysisLimiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
225
S13“Case-Control Studies” OR “Cohort Studies” OR “Epidemiologic Studies” OR “Cross-Sectional Studies” OR “Organizational Case Studies” OR “Cross-Over Studies” OR “Follow-Up Studies” OR “Seroepidemiologic Studies” OR “Evaluation Studies” OR “observational study” OR “observational studies”Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
98
S14S10 AND S11Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
7
S15S10 AND S12Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2
S16S10 AND S13Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
2
S17S14 OR S15 OR S16Limiters - Published Date: 20170101-20171231
Search modes - Boolean/Phrase
Interface - EBSCOhost Research Databases
Search Screen - Advanced Search
Database - International
Pharmaceutical Abstracts
11

ClinicalTrials.gov: April 12, 2017 Original and October 10, 2017 Updated Searches (Combined)

Results: 154

Completed Studies | Studies With Results | Rheumatoid Arthritis | “Adrenal Cortex Hormones” OR corticosteroid OR Methylprednisolone OR prednisone OR prednisolone OR Hydroxychloroquine OR Leflunomide OR Methotrexate OR Sulfasalazine OR Adalimumab OR “certolizumab pegol” OR etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR Sarilumab OR amjevita OR Inflectra OR Erelzi | Adult, Senior | First posted from 07/01/2010 to 10/05/2017

World Health Organization International Clinical Trials Registry Platform (WHO ICTRP):

April 12, 2017 Original Searches and October 10, 2017 Updated Searches (Combined)

  • Two searches, because of character limit:
  • For both:
  • Recruitment status: ALL
  • Date of registration between: July 1, 2010 and October 5, 2017
  • First search:
  • Results: 897 records for 394 trials; 394 (all) imported
  • Condition: Rheumatoid arthritis
  • Intervention: Adrenal Cortex Hormones OR corticosteroid OR Methylprednisolone OR prednisone OR prednisolone OR Hydroxychloroquine OR Leflunomide OR Methotrexate OR Sulfasalazine OR Adalimumab OR certolizumab pegol
  • Second search:
  • Results: 1205 records for 496 trials; 359 imported (137 duplicates)
  • Condition: Rheumatoid arthritis
  • etanercept OR golimumab OR infliximab OR Abatacept OR tocilizumab OR rituximab OR Tofacitinib OR Sarilumab OR Baricitinib OR Sirukumab OR amjevita OR Inflectra OR Erelzi

New York Academy of Medicine Grey Literature Report:

April 12, 2017 Original Searches and October 5, 2017 Update Searches (Combined)

  • “rheumatoid arthritis”
  • Results: 5