In designing the study questions, the EPC consulted several Key Informants who represent the end-users of research. The EPC sought the Key Informant input on the priority areas for research and synthesis. Key Informants are not involved in the analysis of the evidence or the writing of the report. Therefore, in the end, study questions, design, methodological approaches, and/or conclusions do not necessarily represent the views of individual Key Informants.

Key Informants must disclose any financial conflicts of interest greater than $10,000 and any other relevant business or professional conflicts of interest. Because of their role as end-users, individuals with potential conflicts may be retained. The TOO and the EPC work to balance, manage, or mitigate any conflicts of interest.

The list of Key Informants who participated in developing this report follows:

• Ivor S. Douglas, M.D., FRCP
  University of Colorado
  Denver, CO
• Andre C. Kalil, M.D.
  University of Nebraska Medical Center
  Omaha, NE
• Michael B. Kays, Pharm.D., B.C.P.S., FCCP
  Purdue University
  West Lafayette, IN
• Johnalyn Lyles, Pharm.D.
  Centers for Medicare & Medicaid Services
  Baltimore, MD
• Mark Metersky, M.D.
  University of Connecticut
  Farmington, CT