Figure 8.4. Model of lamin assembly.

Figure 8.4Model of lamin assembly

The lamin polypeptides form dimers in which the central α-helical regions of two polypeptide chains are wound around each other. Further assembly may involve the head-to-tail association of dimers to form linear polymers and the side-by-side association of polymers to form filaments.

From: The Nuclear Envelope and Traffic between the Nucleus and Cytoplasm

Cover of The Cell
The Cell: A Molecular Approach. 2nd edition.
Cooper GM.
Sunderland (MA): Sinauer Associates; 2000.
Copyright © 2000, Geoffrey M Cooper.

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