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Chou R, McDonagh MS, Nakamoto E, et al. Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2011 Oct. (Comparative Effectiveness Reviews, No. 38.)
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Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].
Show detailsTable 9Systematic review of tolerability of COX-2s compared with NSAIDs
Review | AE incidence | Withdrawals | ||
---|---|---|---|---|
Overall RR (95% CI) | GI-related RR (95% CI) | Any AE RR (95% CI) | GI-related RR (95% CI) | |
Celecoxib vs. NSAIDs for OA/RA | ||||
Deeks 200250 | - | - | 0.86 (0.72, 1.04) | 0.54 (0.42, 0.71) |
Moore 200551 | 0.96 (0.94, 0.98) | 0.84 (0.81, 0.87) | 0.86 (0.81, 0.91) | 0.75 (0.7, 0.8) |
Chen, 200858 | 0.96 (0.91, 1.0) | 0.75 (0.70, 0.80) | 0.86 (0.73, 1.0) | 0.45 (0.35, 0.56) |
- Table 9, Systematic review of tolerability of COX-2s compared with NSAIDs - Anal...Table 9, Systematic review of tolerability of COX-2s compared with NSAIDs - Analgesics for Osteoarthritis
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