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Chou R, McDonagh MS, Nakamoto E, et al. Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2011 Oct. (Comparative Effectiveness Reviews, No. 38.)

Cover of Analgesics for Osteoarthritis

Analgesics for Osteoarthritis: An Update of the 2006 Comparative Effectiveness Review [Internet].

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Acronyms and Abbreviations

ACR

American College of Rheumatology

ADAPT

Alzheimer’s Disease Anti-Inflammatory Prevention Trial

AE

Adverse event

AHRQ

Agency for Healthcare Research and Quality

ALT

Alanine aminotransferase

AMI

Acute myocardial infarction

AMSTAR

Assessment of Multiple Systematic Reviews

APC

Adenoma Prevention with Celecoxib trial

ARAMIS

Arthritis, Rheumatism, and Aging Medical Information System

ARR

Adjusted relative risk

AST

Aspartate aminotransferase

CCOHTA

Canadian Coordinating Office for Health Technology Assessment

CDME

Central Diabetic Macular Edema trial

CER

Comparative effectiveness review

CHD

Coronary heart disease

CHF

Congestive heart failure

CI

Confidence interval

CLASS

Celecoxib Long-term Arthritis Safety Study

CNS

Central nervous system

COX

Cyclooxygenase

CV

Cardiovascular

DMSO

Dimethyl sulphoxide

EPC

Evidence-based Practice Center

FDA

Food and Drug Administration

GI

Gastrointestinal

GAIT

Glucosamine/chondroitin Arthritis Intervention Trial

H2

Histamine 2

HR

Hazard ratio

HTN

Hypertension

INR

Immediate release

JAMA

Journal of the American Medical Association

JSM

Joint space measurement

JSN

Joint space narrowing

JSW

Joint space width

MeSH

Medical Subject Headings

MI

Myocardial infarction

MUCOSA

Misoprostol Ulcer Complications Outcomes Safety Assessment Trial

NIH

National Institutes of Health

NNT

Number needed to treat

NR

Not reported

NRS LBP

Numerical rating scale for low back pain

NS

Not significant

NSAID

Nonsteroidal anti-inflammatory drug

OA

Osteoarthritis

OR

Odds ratio

OMERACT-OARSI

Outcomes Measures in Arthritis Clinical Trials-Osteoarthritis Research Society International

PCT

Placebo-controlled trial

PICOTS

Populations, Interventions, Comparators, Outcomes, Timing and Setting

POBs

Gastric or duodenal perforation, gastric outlet obstruction, or upper gastrointestinal bleeding

PPI

Proton pump inhibitor

PreSAP

Prevention of colorectal sporadic adenomatous polyps

PUBs

Perforations, symptomatic gastroduodenal ulcers, and upper GI bleeding

PUD

Peptic ulcer disease

qd

Once a day (quaque die)

RA

Rheumatoid arthritis

RCT

Randomized controlled trial

RMDQ

Roland Morris Disability Questionnaire

RR

Relative risk

RRR

Relative risk reduction

SCHIP

State Children s Health Insurance

SF-36

Medical Outcomes Short Form-36

SMD

Standardized mean difference

SR

Sustained release

SR

Rystematic review

SUCCESS-1

Successive Celecoxib Efficacy and Safety Study-1

TARGET

Therapeutic Arthritis Research and Gastrointestinal Event Trial

TEP

Technical Expert Panel

tid

Three times a day (ter in die)

UGIB

Upper gastrointestinal bleeding

UK GPRD

United Kingdom General Practice Research Database

VAS

Visual analog scale

VIGOR

Vioxx Gastrointestinal Outcomes Research

WOMAC

Western Ontario and McMaster Universities Osteoarthritis Index

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