Figure 3 displays a forest plot of RCTs reporting the odds ratio of successful blood pressure control on monotherapy, ARBs versus ACEIs. In the 23 studies the combined estimated odds ratio was 1.083 (95 percent CI 0.937 to 1.252), suggesting that the odds of successful blood pressure control is only 8 percent larger with an ARB alone than with an ACEI alone, and this amount is not statistically significant.

Figure 3Random-effects analysis of RCTs for successful blood pressure control on monotherapy (ARBs vs. ACEIs)

From: Results

Cover of Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension: An Update
Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), and Direct Renin Inhibitors for Treating Essential Hypertension: An Update [Internet].
Comparative Effectiveness Reviews, No. 34.
Sanders GD, Coeytaux R, Dolor RJ, et al.
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