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Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Bookshelf ID: NBK609659PMID: 39626041
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 131986-45-3
SID: 388765364; 433990217
Drug Levels and Effects
Summary of Use during Lactation
Xanomeline is a cholinergic antipsychotic agent that is available in combination with trospium, which is a peripheral anticholinergic agent. No information is available on the clinical use of xanomeline or trospium during breastfeeding. Because trospium is a charged molecule, it is unlikely to pass well into milk. If the mother requires xanomeline, it is not a reason to discontinue breastfeeding. Until more data are available, the xanomeline-trospium combination should only be used with careful infant monitoring, particularly for gastrointestinal side effects such as nausea, vomiting diarrhea, and reflux.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Xanomeline
CAS Registry Number
131986-45-3
Drug Class
Breast Feeding
Milk, Human
Antipsychotic Agents
Parasympathomimetics
Psychotropic Drugs
Muscarinic Agonists
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Xanomeline - Drugs and Lactation Database (LactMed®)Xanomeline - Drugs and Lactation Database (LactMed®)
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