Hb Bart’s hydrops foetalis syndrome is inherited in a recessive manner, requiring the inheritance of two α0-thalassaemia alleles. Given the severity of the syndrome to both the fetus and the mother, prenatal diagnosis is strongly recommended for carrier couples of α0-thalassaemia.

From: Chapter 1, EPIDEMIOLOGY, PATHOPHYSIOLOGY AND DIAGNOSIS OF α-THALASSAEMIA

Cover of Guidelines for the Management of α-Thalassaemia
Guidelines for the Management of α-Thalassaemia [Internet].
Amid A, Lal A, Coates TD, et al., editors.
Nicosia (Cyprus): Thalassaemia International Federation; 2023.
© Thalassaemia International Federation.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.