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Guthrie B, Rogers G, Livingstone S, et al. The implications of competing risks and direct treatment disutility in cardiovascular disease and osteoporotic fracture: risk prediction and cost effectiveness analysis. Southampton (UK): National Institute for Health and Care Research; 2024 Feb. (Health and Social Care Delivery Research, No. 12.04.)

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The implications of competing risks and direct treatment disutility in cardiovascular disease and osteoporotic fracture: risk prediction and cost effectiveness analysis.

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FIGURE 51. Updated model, including adjustment for competing risk of non-cardiovascular death: one-way sensitivity analysis for high-intensity statins (atorvastatin 20 mg/day) compared with no treatment (60-year-olds, 50 : 50 men : women, 10% 10-year cardiovascular event risk).

FIGURE 51

Updated model, including adjustment for competing risk of non-cardiovascular death: one-way sensitivity analysis for high-intensity statins (atorvastatin 20 mg/day) compared with no treatment (60-year-olds, 50 : 50 men : women, 10% 10-year cardiovascular event risk). Thirty most influential parameters shown. Positive incremental NHB implies that high-intensity statins is the preferred option (i.e. it would be associated with an ICER of £20,000/QALY or better vs. no treatment). CV, cardiovascular; RR, relative risk.

From: Appendix 8, Full results from cost–utility model assessing statins for the primary prevention of cardiovascular disease including adjustment for competing risk

Copyright © 2024 Guthrie et al.

This work was produced by Guthrie et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.

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