Contents

• Introduction
• Project methods
• Chapter 1. High dietary protein intake (including amino acid intake) and acute adverse health effects
  Marlana Bates, Charlotte Bahnfleth, Natasha Cole, Molly Higgins, Sara Scinto-Madonich, Joanne Spahn, and Julie Obbagy.
  • Specific methods to conduct this evidence scan
  • Results
• Chapter 2. Protein intake and chronic disease risk
  Joanne Spahn, Charlotte Bahnfleth, Marlana Bates, Natasha Cole, Molly Higgins, and Sara Scinto-Madonich.
  • Specific methods to conduct this evidence scan
  • Results
• Chapter 3. Average daily dietary protein intake (including amino acid intake) requirement
  Charlotte Bahnfleth, Marlana Bates, Natasha Cole, Molly Higgins, Sara Scinto-Madonich, and Joanne Spahn.
  • Specific methods to conduct this evidence scan
  • Results
• References for all three evidence scan chapters
• Acknowledgments and funding
• Appendices
  • Appendix 0. Abbreviations
  • Appendix 1-a. Literature search strategy for high protein intake and acute adverse health effects evidence scan
  • Appendix 1-b. Excluded articles for high protein intake and acute adverse health effects evidence scan
  • Appendix 2-a. Literature search strategy for protein intake and chronic disease risk evidence scan
  • Appendix 2-b. Literature search strategy for protein intake and length of sleep evidence scan (supplemental to chronic disease risk scan)
  • Appendix 2-c. Literature search strategy for protein intake and appetite/satiety evidence scan (supplemental to chronic disease risk scan)
  • Appendix 2-d. Bibliography of excluded reviews identified that evaluated plant and/or animal protein intake (not total protein intake)
  • Appendix 2-e. Excluded articles for protein intake and chronic disease risk evidence scan
  • Appendix 2-f. Excluded articles for protein intake and sleep duration evidence scan (supplemental to chronic disease risk scan)
  • Appendix 2-g. Excluded articles for protein intake and appetite/satiety evidence scan (supplemental to chronic disease risk scan)
  • Appendix 2-h. AMSTAR 2 assessment of review quality and funding source by outcome category^,
  • Appendix 2-i. Duplication assessment for protein intake and all-cause mortality evidence
  • Appendix 2-j. Duplication assessment for protein intake and bone health evidence
  • Appendix 2-k. Duplication assessment for protein intake and cardiovascular disease risk evidence
  • Appendix 2-l. Duplication assessment for protein intake and diabetes risk evidence
  • Appendix 2-m. Duplication assessment for protein intake and renal health evidence
  • Appendix 2-n. Duplication assessment for protein intake and sarcopenia evidence
  • Appendix 3-a. Literature search strategy for the protein requirements evidence scan
  • Appendix 3-b. Excluded articles for the protein requirements evidence scan

Suggested citation:

Nutrition Evidence Systematic Review Team. Dietary Protein Intake: A Series of Evidence Scans on Acute Adverse Health Effects, Chronic Disease Risk, and Daily Requirements. Protein DRI Update. Alexandria, VA: U.S. Department of Agriculture, Food and Nutrition Service, Center for Nutrition Policy and Promotion, March 2022. Available at: https://doi.org/10.52570/NESR.DRI2022.ES01

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