IARC Monographs
In 1969, the International Agency for Research on Cancer (IARC) initiated a programme on the evaluation of the carcinogenic hazard of chemicals to humans, involving the production of critically evaluated monographs on individual chemicals. The programme was subsequently expanded to include evaluations of carcinogenic hazards associated with exposures to complex mixtures, lifestyle factors and biological and physical agents, as well as those in specific occupations. The objective of the programme is to elaborate and publish in the form of monographs critical reviews of data on carcinogenicity for agents to which humans are known to be exposed and on specific exposure situations; to evaluate these data in terms of cancer hazard to humans with the help of international working groups of experts in carcinogenesis and related fields; and to identify gaps in evidence. The lists of IARC evaluations are regularly updated and are available on the internet at https://monographs.iarc.who.int/.
This programme has been supported since 1982 by Cooperative Agreement U01 CA33193 with the United States National Cancer Institute, Department of Health and Human Services. Additional support has been provided since 1986 by the European Commission Directorate-General for Employment, Social Affairs, and Inclusion, initially by the Unit of Health, Safety and Hygiene at Work, and since 2014 by the European Union Programme for Employment and Social Innovation “EaSI” (for further information please consult: https://ec.europa.eu/social/easi). Support has also been provided since 1992 by the United States National Institute of Environmental Health Sciences, Department of Health and Human Services. The contents of this volume are solely the responsibility of the Working Group and do not necessarily represent the official views of the United States National Cancer Institute, the United States National Institute of Environmental Health Sciences, the United States Department of Health and Human Services, or the European Commission.
Co-funded by the European Union
Published by the International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
©International Agency for Research on Cancer, 2022
On-line publication, August 2022
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About the cover: Worker applying a yellow epoxy protective resin to a floor. 1,1,1-Trichloroethane, N-methylolacrylamide, and isophorone are used in commercial resins..
Source: © AdobeStock.com/Doralin
How to cite: IARC (2022). 1,1,1-Trichloroethane and four other industrial chemicals. IARC Monogr Identif Carcinog Hazards Hum, 130:1–368.
IARC Library Cataloguing-in-Publication Data
Names: IARC Working Group on the Identification of Carcinogenic Hazards to Humans.
Title: 1,1,1-Trichloroethane and four other industrial chemicals.
Description: Lyon: International Agency for Research on Cancer, 2022. | Series: IARC monographs on the identification of carcinogenic hazards to humans, ISSN 1017-1606; v. 130. | “This publication represents the views and expert opinions of an IARC Working Group on the Identification of Carcinogenic Hazards to Humans, which met remotely, 7–22 October 2021.” | Includes bibliographical references.
Identifiers: ISBN 9789283201700 (pbk.) | ISBN 9789283201977 (ebook)
Subjects: MESH: Carcinogens--toxicity. | Neoplasms--chemically induced. | Trichloroethanes--adverse effects. | Phenylhydrazines--adverse effects. | Diphenylamine--adverse effects. | Acrylamides--adverse effects. | Cyclohexanones--adverse effects. | Risk Factors.
Classification: NLM W1