Contents

• Clinical Review
  • Executive Summary
  • Introduction
  • Stakeholder Perspectives
  • Clinical Evidence
  • Discussion
  • Conclusions
  • Abbreviations
  • Appendix 1. Literature Search Strategy
  • Appendix 2. Excluded Studies
  • References
• Pharmacoeconomic Review
  • Executive Summary
  • Stakeholder Input Relevant to the Economic Review
  • Economic Review
  • Abbreviations
  • Appendix 1. Cost Comparison Table
  • Appendix 2. Submission Quality
  • Appendix 3. Additional Information on the Submitted Economic Evaluation
  • Appendix 4. Additional Details on the CADTH Reanalyses and Sensitivity Analyses of the Economic Evaluation
  • Appendix 5. Submitted BIA and CADTH Appraisal
  • References
• Ethics Review
  • Summary
  • Objectives
  • Research Questions
  • Methods
  • Results
  • Abbreviations
  • References
• Stakeholder Input
  • Patient Input
  • Clinician Input

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Sponsor: Advanced Accelerator Applications Canada, Inc.

Therapeutic area: Metastatic castration-resistant prostate cancer