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Accelerating the Development and Uptake of Rapid Diagnostics to Address Antibiotic Resistance
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Board on Global Health; Forum on Microbial Threats; Forum on Medical and Public Health Preparedness for Disasters and Emergencies; Forum on Drug Discovery, Development, and Translation; Editors: Carolyn Shore, Rapporteur and Erin Hammers Forstag, Rapporteur.
The use and misuse of antibiotics contributes to the rise in drug-resistant bacteria - a serious and worsening threat to human health. The development and use of rapid point-of-care diagnostics in the healthcare setting plays an important role in avoiding unnecessary use of antimicrobials by providing clinicians with the right information at the right time to help them make decisions about appropriate drug treatment for patients. Diagnostics also have the capacity to support early detection and diagnosis of drug-resistant bacterial infections, enable disease surveillance, and help prevent disease spread. The National Academies Forum on Drug Discovery, Development, and Translation; Forum on Medical and Public Health Preparedness for Disasters and Emergencies; and Forum on Microbial Threats hosted an October 2022 workshop exploring the current landscape of rapid diagnostics to address antibiotic resistance, challenges and opportunities for spurring innovation, and practical next steps for accelerating the development of new diagnostic tools.
Contents
- The National Academies of SCIENCES • ENGINEERING • MEDICINE
- PLANNING COMMITTEE ON ACCELERATING THE DEVELOPMENT AND UPTAKE OF RAPID DIAGNOSTICS TO ADDRESS ANTIBIOTIC RESISTANCE
- FORUM ON DRUG DISCOVERY, DEVELOPMENT, AND TRANSLATION
- FORUM ON MEDICAL AND PUBLIC HEALTH PREPAREDNESS FOR DISASTERS AND EMERGENCIES
- FORUM ON MICROBIAL THREATS
- Reviewers
- Acknowledgments
- Acronyms and Abbreviations
- 1. Introduction
- 2. Exploring the Need for Rapid Diagnostics
- 3. Lessons Learned from the COVID-19 Pandemic
- 4. Incentives at the Intersection of Drug Development and Complementary Diagnostics
- 5. Health Equity Considerations
- 6. Diagnostic Stewardship
- 7. Exploring Potential Policy Options
- References
- Appendix A:. Workshop Agenda
- Appendix B. Biographical Sketches of the Workshop Planning Committee and Speakers
Suggested citation:
National Academies of Sciences, Engineering, and Medicine. 2023. Accelerating development and uptake of rapid diagnostics to address antibiotic resistance: Proceesings of a workshop. Washington, DC: The National Academies Press. https://doi.org/10.17226/27008.
Digital Object Identifier: https://doi.org/10.17226/27008
This publication is available from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.
Printed in the United States of America.
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