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Bookshelf ID: NBK588735PMID: 36701502
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 79338-84-4
Drug Levels and Effects
Summary of Use during Lactation
Tapinarof has not been studied during breastfeeding. Because it is poorly absorbed after topical application, it is considered a low risk to the nursing infant.[1] Do not apply tapinarof directly to the nipple and areola and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
(Psoriasis) Adalimumab, Certolizumab Pegol, Etanercept, Infliximab, Phototherapy, Tretinoin
References
- 1.
- Yaghi M, McMullan P, Truong TM, et al. Safety of dermatologic medications in pregnancy and lactation: An Update - Part II: Lactation. J Am Acad Dermatol 2024;91:651-68. [PubMed: 38280680]
Substance Identification
Substance Name
Tapinarof
CAS Registry Number
79338-84-4
Drug Class
Breast Feeding
Lactation
Milk, Human
Dermatological Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Review Trifarotene.[Drugs and Lactation Database (...]Review Trifarotene.. Drugs and Lactation Database (LactMed®). 2006
- Review A Review of Topical Tapinarof for the Treatment of Plaque Psoriasis.[Ann Pharmacother. 2024]Review A Review of Topical Tapinarof for the Treatment of Plaque Psoriasis.Grossmann MC, Pixley JN, Feldman SR. Ann Pharmacother. 2024 Jan; 58(1):76-85. Epub 2023 Apr 19.
- Tapinarof and its structure-activity relationship for redox chemistry and phototoxicity on human skin keratinocytes.[Free Radic Biol Med. 2024]Tapinarof and its structure-activity relationship for redox chemistry and phototoxicity on human skin keratinocytes.Zatloukalova M, Hanyk J, Papouskova B, Kabelac M, Vostalova J, Vacek J. Free Radic Biol Med. 2024 Oct; 223:212-223. Epub 2024 Jul 26.
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- Tapinarof - Drugs and Lactation Database (LactMed®)Tapinarof - Drugs and Lactation Database (LactMed®)
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