U.S. flag

An official website of the United States government

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Gupta A, Fine SM, Vail RM, et al. Prevention and Management of Hepatitis B Virus Infection in Adults With HIV [Internet]. Baltimore (MD): Johns Hopkins University; 2022 Aug.

Cover of Prevention and Management of Hepatitis B Virus Infection in Adults With HIV

Prevention and Management of Hepatitis B Virus Infection in Adults With HIV [Internet].

Show details
Figure 2. Algorithm for HBV Screening and Vaccination in Patients With HIV.

Figure 2Algorithm for HBV Screening and Vaccination in Patients With HIV

Abbreviations: anti-HBc, hepatitis B core antibody; anti-HBs, hepatitis B surface antibody; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus.

Notes:

a

In patients with positive anti-HBc, negative anti-HBs, and negative HBsAg test results, vaccinate with 1 standard dose of HBV vaccine and check anti-HBs titer after 8 weeks. If titer is <100 mlU/mL, complete remaining doses in the vaccine series and recheck titer 8 weeks after the last vaccine.

b

In patients with anti-HBs levels <10 mlU/mL (vaccine nonresponse), revaccination is recommended with the Heplisav-B vaccine series or a double dose of the vaccine series previously administered.

c

A patient who is negative for all serologies and who does not respond to revaccination may have a primary nonresponse or chronic infection. HBV DNA testing may be used to detect the presence of chronic HBV infection.

From: Prevention and Management of Hepatitis B Virus Infection in Adults With HIV

Copyright © Johns Hopkins University Clinical Guidelines Program 2000-2024. The Clinical Guidelines Program, a collaborative effort of the NYSDOH AI and the Johns Hopkins University School of Medicine, Division of Infectious Diseases, encourages the use, reproduction, and distribution of original documents and related graphics from this program website accompanied by a full citation of source that includes: Author(s). Committee. Title. Date of publication. Full URL. Date accessed. Links to pages on this Clinical Guidelines Program website are also encouraged and may be created without seeking permission. Requests to adapt material, i.e., to change or alter in any way material from this website for inclusion in another publication, should be sent to aiguidelines@jhmi.edu. Please include detailed information about the intended use and desired adaptations.

This book is licensed under the terms of the Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0).

Views

  • Cite this Page
  • PDF version of this title (680K)

Other titles in this collection

Related information

Recent Activity

ClearTurn OffTurn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...