Structured Abstract

Contents

• Acknowledgments
• 1. Introduction
  • Background
  • Objectives
  • Organization of This Report
• 2. Calculation of Harmonized Depression Outcome Measures in Registries
  • Introduction
  • Methods for Calculating the Measures in Patient Registries
  • Findings
  • Lessons Learned
• 3. Calculation of Harmonized Depression Outcome Measures in a Health System
  • Introduction
  • Design and Development of SMART on FHIR App
  • Research Study To Assess SMART on FHIR App
  • Lessons Learned
• 4. Use of Harmonized Depression Outcome Measures for Research
  • Introduction
  • Assessment of Registry Data Availability
  • Evaluation of Registry Data Quality
  • Pilot Data Analysis
  • Lessons Learned
• 5. Resources To Support Future Use of Harmonized Depression Outcome Measures
  • Introduction
  • Prioritized Research Agenda
  • Data Use & Governance Toolkit
  • Use of Natural Language Processing for Extracting Measures Data
  • FHIR Implementation Guide and Libraries
  • SMART on FHIR App
• 6. Implications for Future Use of Harmonized Outcome Measures
  • Key Findings and Lessons Learned
  • Future Research Needs
  • Implications for Future Implementations
• 7. Conclusions
• 8. References
• Appendixes
  • Appendix A. Harmonized Depression Outcome Measures
  • Appendix B. Artifacts Submitted Separately
  • Appendix C. Clinician Survey

Suggested citation:

Leavy MB, Boussios C, Phillips RL, Clarke D, Sarvet B, Boxwala A, Gliklich R. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression: Final Report. (Prepared by OM1, Inc. and its subcontractors the American Board of Family Medicine, American Psychiatric Association, Baystate Health, and Elimu Informatics under Contract No. 75Q80119C00005.) AHRQ Publication No. 21(22)-EHC032. Rockville, MD: Agency for Healthcare Research and Quality; June 2022. DOI: 10.23970/AHRQEPCWHITEPAPERDEPRESSIONFINAL. Posted final reports are located on the Effective Health Care Program search page.

This report is based on research conducted by OM1, Inc. with subcontractors the American Board of Family Medicine, American Psychiatric Association, Baystate Health, and Elimu Informatics under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 75Q80119C00005). This work is supported by the Office of the Secretary Patient-Centered Outcomes Research Trust Fund under Interagency Agreement 18-596R-18. The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the United States (U.S.) Department of Health and Human Services.

None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report.

The information in this report is intended to help healthcare decision makers—patients and clinicians, health system leaders, and policymakers, among others—make well-informed decisions and thereby improve the quality of healthcare services. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients.

This report is made available to the public under the terms of a licensing agreement between the author and AHRQ. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted materials is prohibited without the express permission of copyright holders.

AHRQ appreciates appropriate acknowledgment and citation of its work. Suggested language for acknowledgment: This work was based on a Final Report, Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression, by OM1, Inc., with subcontractors the American Board of Family Medicine, American Psychiatric Association, Baystate Health, and Elimu Informatics through the Agency for Healthcare Research and Quality (AHRQ).