FIGURE 23.4. [Biosynthesis of N-glycans and their...]. - Essentials of Glycobiology

Warning: The NCBI web site requires JavaScript to function. more...

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.

Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology [Internet]. 4th edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022. doi: 10.1101/glycobiology.4e.23

Essentials of Glycobiology [Internet]. 4th edition.

Show details

Contents

FIGURE 23.4.

Biosynthesis of N-glycans and their transfer to -Asn-X-Ser/Thr- sequons of newly synthesized glycoproteins in the fungal endoplasmic reticulum (ER). Individual steps in the biosynthesis pathway from dolichol phosphate (simplest structure at top right) and the structure of dolichol (lower left) are shown. Biosynthetic steps identified by mutants in yeast are shown as genes designated as ALG or SEC. The structure of the intermediate Glc₃Man₉GlcNAc₂-P-P-Dol, which is common to yeast and mammals, is shown (lower right).

Download Teaching Slide (PPTX, 24M)

From: Chapter 23, Fungi

The content of this book is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 Unported license. To view the terms and conditions of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/

Contents

Views

Cite this Page
Routier FH, Doering TL, Cummings RD, et al. Fungi. In: Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology [Internet]. 4th edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022. FIGURE 23.4. [Biosynthesis of N-glycans and their...]. doi: 10.1101/glycobiology.4e.23