FIGURE 47.4.. In normal physiology platelets, leukocytes, and endothelial cells interact via selectins and selectin ligands.

FIGURE 47.4.

In normal physiology platelets, leukocytes, and endothelial cells interact via selectins and selectin ligands. In invasive carcinoma, interactions that promote invasion occur between tumor cells expressing selectin ligands and selectins on endothelial cells and platelets. (Modified from Stevenson JL, et al. 2005. Clin Cancer Res 11: 7003–7011.)

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From: Chapter 47, Glycosylation Changes in Cancer

Cover of Essentials of Glycobiology
Essentials of Glycobiology [Internet]. 4th edition.
Varki A, Cummings RD, Esko JD, et al., editors.
Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022.
Copyright © 2022 The Consortium of Glycobiology Editors, La Jolla, California; published by Cold Spring Harbor Laboratory Press; doi:10.1101/glycobiology.4e.47. All rights reserved.

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