NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Understanding the Role of the Immune System in Improving Tissue Regeneration
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Forum on Regenerative Medicine; Editors: Anna Nicholson, Rapporteur, Samantha N. Schumm, Rapporteur, and Sarah H. Beachy, Rapporteur.
The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve outcomes of tissue repair and regeneration in patients. The workshop, titled “Understanding the Role of the Immune System in Improving Tissue Regeneration,” explored the role of the immune system in the success or failure of regenerative medicine therapies. Participants considered potential strategies to effectively “prepare” patients' immune systems to accept regenerative therapies and increase the likelihood of successful clinical outcomes and also discussed risks associated with modulating the immune system. This Proceedings of a Workshop highlights the presentations and discussions that occurred during the workshop.
Contents
- The National Academies of SCIENCES • ENGINEERING • MEDICINE
- PLANNING COMMITTEE ON UNDERSTANDING THE ROLE OF THE IMMUNE SYSTEM IN IMPROVING TISSUE REGENERATION
- FORUM ON REGENERATIVE MEDICINE
- Reviewers
- Acknowledgments
- Acronyms and Abbreviations
- 1. Introduction
- 2. Tissue Homeostasis, Inflammation, and Repair
- 3. Lessons Learned from Immune Tolerance and Graft Acceptance
- 4. Engineering of Allogeneic Donor Cells for Acceptance by the Host's Immune System
- 5. Endogenous Regeneration and the Role of the Local Environment in Repair
- 6. Modulating the Host Immune System to Create a Pro-Regenerative Environment
- 7. Tools and Preclinical Models for Monitoring and Optimizing the Host's Pro-Regenerative Environment
- 8. Harnessing the Immune System to Improve Patient Outcomes
- REFERENCES
- Appendix A. Workshop Agenda
- Appendix B. Speaker Biographical Sketches
- Appendix C. Statement of Task
Suggested citation:
National Academies of Sciences, Engineering, and Medicine. 2022. Understanding the role of the immune system in improving tissue regeneration: Proceedings of a workshop. Washington, DC: The National Academies Press. https://doi.org/10.17226/26551.
Digital Object Identifier: https://doi.org/10.17226/26551
Additional copies of this report are available for sale from the National Academies Press, 500 Fifth Street, NW, Keck 360, Washington, DC 20001; (800) 624-6242 or (202) 334-3313; http://www.nap.edu.
Printed in the United States of America
- NLM CatalogRelated NLM Catalog Entries
- Review Applying Systems Thinking to Regenerative Medicine: Proceedings of a Workshop[ 2021]Review Applying Systems Thinking to Regenerative Medicine: Proceedings of a WorkshopNational Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Forum on Regenerative Medicine, Beachy SH, Nicholson A, Teferra L, Hackmann M, Addie S. 2021 Mar 26
- Review Systematizing the One Health Approach in Preparedness and Response Efforts for Infectious Disease Outbreaks: Proceedings of a Workshop[ 2022]Review Systematizing the One Health Approach in Preparedness and Response Efforts for Infectious Disease Outbreaks: Proceedings of a WorkshopNational Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Global Health;Forum on Microbial Threats, Nicholson A, Minicucci C, Liao J, Biffl C. 2022 Jan 11
- Review The Role of Digital Health Technologies in Drug Development: Proceedings of a Workshop[ 2020]Review The Role of Digital Health Technologies in Drug Development: Proceedings of a WorkshopNational Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Roundtable on Genomics and Precision Health; Forum on Drug Discovery, Development, and Translation, Shore C, Beachy SH, Nicholson A, Addie S, Hackmann M, Khandekar E. 2020 Aug 28
- Review Reducing Inequalities Between Lesbian, Gay, Bisexual, Transgender, and Queer Adolescents and Cisgender, Heterosexual Adolescents: Proceedings of a Workshop[ 2022]Review Reducing Inequalities Between Lesbian, Gay, Bisexual, Transgender, and Queer Adolescents and Cisgender, Heterosexual Adolescents: Proceedings of a WorkshopNational Academies of Sciences, Engineering, and Medicine; Division of Behavioral and Social Sciences and Education; Board on Children, Youth, and Families, Forstag EH. 2022 Jan 6
- Review Exploring the State of the Science in the Field of Regenerative Medicine: Challenges of and Opportunities for Cellular Therapies: Proceedings of a Workshop[ 2017]Review Exploring the State of the Science in the Field of Regenerative Medicine: Challenges of and Opportunities for Cellular Therapies: Proceedings of a WorkshopNational Academies of Sciences, Engineering, and Medicine, Health and Medicine Division, Board on Health Sciences Policy, Forum on Regenerative Medicine. 2017 Mar 15
- Understanding the Role of the Immune System in Improving Tissue RegenerationUnderstanding the Role of the Immune System in Improving Tissue Regeneration
Your browsing activity is empty.
Activity recording is turned off.
See more...