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National Guideline Alliance (UK). Identifying and managing respiratory disorders associated with cerebral palsy: protocols for monitoring respiratory health: Cerebral palsy in adults: Evidence review C1. London: National Institute for Health and Care Excellence (NICE); 2019 Jan. (NICE Guideline, No. 119.)

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Identifying and managing respiratory disorders associated with cerebral palsy: protocols for monitoring respiratory health: Cerebral palsy in adults: Evidence review C1.

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Table 2Summary of included studies

StudyDesignParticipantsIndex TestReference standardOutcomes
Lennon 2015 Systematic review of cross-sectional studies

117 teenagers or adults with cerebral palsy (ages ranged from 16 to 67 years), reported in 7 studies.

All were ambulatory or self-propelled wheelchair users. GMFCS I (N=45), II (N=25), not reported (N=57)

3 studies (N=42) included only athletes.

USA & Netherlands

Lab based aerobic capacity tests:
  • Bicycle ergometer
  • Wheelchair ergometer
Field based aerobic capacity tests:
  • 6 minute walk test
Lab based maximal aerobic capacity tests measuring
  • VO2 plateau
  • Heart rate
  • Respiratory exchange ratio
  • Feasibility
  • Validity
  • Reliability
Lampe 2014 Cross-sectional study

46 adults with CP, age 22 to 59 years.

GMFCS I (N=4), II (N=3), III (N=18) and IV (N=21).

16/46 had scoliosis.

Germany

  • Lung vital capacity (using spirometer)
  • Chest expansion
Oxygen saturation (pulse oximeter)
  • Sensitivity
  • Specificity

CP: cerebral palsy; GMFCS: Gross Motor Function Classification System; N: number of participants in study; USA: United States of America; VO2, oxygen volume

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